Diverticular Disease

Common Name(s)

Diverticular Disease

Diverticular disease is characterized by the formation of diverticula, or small out-pouchings and pockets, in the walls of the colon (the last segment of the gastrointestinal tract which digests and carries food through the body). There are three types of diverticular diseases: diverticulosis, diverticular bleeding, and diverticulitis. The specific causes of diverticular diseases are unknown, but they are more common in people with a low fiber diet, which leads to increased pressure in the colon resulting in pocket formation. In diverticulosis (uncomplicated diverticular disease) the pockets form but do not become infected or inflamed, and therefore no symptoms occur. Infection or inflammation of the pockets (diverticulitis) can cause abdominal (belly) pain, fever, as well as other complications that may require surgery. Diverticular bleeding results in blood in the stool and bleeding from the rectum and anus, and may also require immediate medical attention. Diverticular diseases are managed by maintaining a high fiber diet (e.g. grains, vegetables), although episodes of diverticulitis and diverticular bleeding may require antibiotics, hospitalization, and potentially surgery.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diverticular Disease" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

Last Updated: 28 Feb 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diverticular Disease" for support, advocacy or research.

Association of Gastrointestinal Motility Disorders, Inc. (AGMD)

AGMD is a nonprofit international organization which serves as an integral educational resource concerning digestive motility diseases and disorders. It also functions as an important information base for members of the medical and scientific communities. In addition, it provides a forum for patients suffering from digestive motility diseases and disorders as well as their families and members of the medical community.

http://www.agmd-gimotility.org

Last Updated: 28 Feb 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diverticular Disease" returned 223 free, full-text research articles on human participants. First 3 results:

Socioeconomic characteristics and comorbidities of diverticular disease in Sweden 1997-2012.
 

Author(s): Maziar Nikberg, Jianguang Ji, Jerzy Leppert, Kristina Sundquist, Abbas Chabok

Journal: Int J Colorectal Dis. 2017 Nov;32(11):1591-1596.

 

This study aimed to evaluate the association of socioeconomic status and comorbidities with uncomplicated and complicated diverticular disease (DD) in Sweden.

Last Updated: 31 Dec 1969

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Economic burden of diverticular disease: An observational analysis based on real world data from an Italian region.
 

Author(s): F S Mennini, P Sciattella, A Marcellusi, B Toraldo, M Koch

Journal: Dig Liver Dis. 2017 Sep;49(9):1003-1008.

 

Diverticular disease (DD), a herniation of the colonic mucosa through the muscle layer, covers a wide variety of conditions associated with the presence of diverticula in the colon. The most serious form is an acute episode of diverticulitis, which can lead to hospitalization and ...

Last Updated: 31 Dec 1969

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Genito-Urinary Function and Quality of Life after Elective Totally Laparoscopic Sigmoidectomy after at Least One Episode of Complicated Diverticular Disease According to Two Different Vascular Approaches: the IMA Low Ligation or the IMA Preservation.
 

Author(s): Giulio Mari, Jacopo Crippa, Andrea Costanzi, Michele Mazzola, Carmelo Magistro, Giovanni Ferrari, Dario Maggioni

Journal: Chirurgia (Bucur). ;112(2):136-142.

 

The arterial ligation during elective laparoscopic sigmoidectomy for diverticular disease can affect genito-urinary function injuring the superior hypogastric plexus, and can weaken the distal colonic stump arterial perfusion. Ligation of the inferior mesenteric artery distal to the ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diverticular Disease" returned 45 free, full-text review articles on human participants. First 3 results:

Diverticular disease practice points.
 

Author(s): William McSweeney, Havish Srinath

Journal: Aust Fam Physician. 2017 Nov;46(11):829-832.

 

Diverticular disease and its spectrum of complications are increasingly encountered in the Australian population. Accurate management of patients before and after an acute episode entails extension beyond the acute event to include dietary advice and colonoscopy.

Last Updated: 31 Dec 1969

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The CDD System in Computed Tomographic Diagnosis of Diverticular Disease.
 

Author(s): Daniel Pustelnik, Fabian Henry Jürgen Elsholtz, Christian Bojarski, Bernd Hamm, Stefan Markus Niehues

Journal: Rofo. 2017 Aug;189(8):740-747.

 

 This overview sums up the Classification of Diverticular Disease (CDD) with regard to its application in computed tomographic diagnosis and briefly recapitulates its targeted advantages over preliminary systems. Primarily, application of the CDD in computed tomography diagnostics ...

Last Updated: 31 Dec 1969

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Tobacco smoking and the risk of diverticular disease - a systematic review and meta-analysis of prospective studies.
 

Author(s): D Aune, A Sen, M F Leitzmann, S Tonstad, T Norat, L J Vatten

Journal: Colorectal Dis. 2017 Jul;19(7):621-633.

 

This systematic review and meta-analysis aimed to clarify whether tobacco smoking is associated with an increased risk of diverticular disease.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Lactoferrin for the Treatment of Symptomatic Uncomplicated Diverticular Disease
 

Status: Recruiting

Condition Summary: Diverticular Disease; Symptomatic Uncomplicated Diverticular Disease

 

Last Updated: 8 Aug 2018

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PREDICtors for Quality of Life After Sigmoidectomy for DIVerticular Disease
 

Status: Recruiting

Condition Summary: Diverticular Disease of Colon; Quality of Life

 

Last Updated: 16 May 2018

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A New Treatment for Zenker's Diverticulum-submucosal Tunneling Endoscopic Septum Division
 

Status: Recruiting

Condition Summary: Zenker Diverticulum

 

Last Updated: 2 Aug 2018

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