Ebola Virus Disease

Common Name(s)

Ebola Virus Disease

Ebola virus disease (EVD), formerly known as Ebola haemorrhagic fever, is an extremely serious and deadly disease that has historically spread through remote areas of Central and West Africa. The Ebola virus spreads first by animal-to-human, then by human-to-human contact through blood, secretions, organs, or other bodily fluids. The Ebola virus however cannot be spread through the air such as by a cough or sneeze. This means it is not as highly contagious as many other viruses. Ebola is considered highly infectious, which means if you become infected with the virus, you are likely to become very sick. Symptoms of Ebola virus include sudden onset of a high fever, weakness, vomiting, diarrhea, headaches, rash, and impaired kidney and liver functions. As the disease progresses, internal bleeding occurs as does bleeding from the eyes. Patients often experience dehydration, which is treated with fluids containing high amounts of electrolytes. Although there is currently no approved vaccine or treatment for EVD, there are several promising treatments and a possible vaccine under development. At present, early medical support to lessen the effect of the symptoms is the best way to reduce chance of death. Standard infectious disease isolation protocols can help stop the spread of EVD.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ebola Virus Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ebola Virus Disease" returned 310 free, full-text research articles on human participants. First 3 results:

Establishing Ebola Virus Disease (EVD) diagnostics using GeneXpert technology at a mobile laboratory in Liberia: Impact on outbreak response, case management and laboratory systems strengthening.
 

Author(s): Philomena Raftery, Orla Condell, Christine Wasunna, Jonathan Kpaka, Ruth Zwizwai, Mahmood Nuha, Mosoka Fallah, Maxwell Freeman, Victoria Harris, Mark Miller, April Baller, Moses Massaquoi, Victoria Katawera, John Saindon, Philip Bemah, Esther Hamblion, Evelyn Castle, Desmond Williams, Alex Gasasira, Tolbert Nyenswah

Journal:

 

The 2014-16 Ebola Virus Disease (EVD) outbreak in West Africa highlighted the necessity for readily available, accurate and rapid diagnostics. The magnitude of the outbreak and the re-emergence of clusters of EVD cases following the declaration of interrupted transmission in Liberia, ...

Last Updated: 31 Dec 1969

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Knowledge, Attitudes, and Practices Related to Ebola Virus Disease at the End of a National Epidemic - Guinea, August 2015.
 

Author(s): Mohamed F Jalloh, Susan J Robinson, Jamaica Corker, Wenshu Li, Kathleen Irwin, Alpha M Barry, Paulyne Ngalame Ntuba, Alpha A Diallo, Mohammad B Jalloh, James Nyuma, Musa Sellu, Amanda VanSteelandt, Megan Ramsden, LaRee Tracy, Pratima L Raghunathan, John T Redd, Lise Martel, Barbara Marston, Rebecca Bunnell

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Health communication and social mobilization efforts to improve the public's knowledge, attitudes, and practices (KAP) regarding Ebola virus disease (Ebola) were important in controlling the 2014-2016 Ebola epidemic in Guinea (1), which resulted in 3,814 reported Ebola cases and 2,544 ...

Last Updated: 31 Dec 1969

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Reporting Deaths Among Children Aged <5 Years After the Ebola Virus Disease Epidemic - Bombali District, Sierra Leone, 2015-2016.
 

Author(s): Amanda L Wilkinson, Reinhard Kaiser, Mohamed F Jalloh, Mamudi Kamara, Dianna M Blau, Pratima L Raghunathan, Alpha Kamara, Umaru Kamara, Nathaniel Houston-Suluku, Kevin Clarke, Amara Jambai, John T Redd, Sara Hersey, Brima Osaio-Kamara

Journal:

 

Mortality surveillance and vital registration are limited in Sierra Leone, a country with one of the highest mortality rates among children aged <5 years worldwide, approximately 120 deaths per 1,000 live births (1,2). To inform efforts to strengthen surveillance, stillbirths and ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ebola Virus Disease" returned 51 free, full-text review articles on human participants. First 3 results:

Neuropsychological long-term sequelae of Ebola virus disease survivors - A systematic review.
 

Author(s): Felix Lötsch, Jenny Schnyder, Abraham Goorhuis, Martin P Grobusch

Journal: Travel Med Infect Dis. ;18():18-23.

 

The recent West African Ebola virus disease (EVD) outbreak had catastrophic impact on populations, health care systems and economies of the affected countries. Somatic symptoms have been reported to persist long beyond the acute infection. This review was conducted to provide an overview ...

Last Updated: 31 Dec 1969

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Insights from clinical research completed during the west Africa Ebola virus disease epidemic.
 

Author(s): Amanda Rojek, Peter Horby, Jake Dunning

Journal: Lancet Infect Dis. 2017 Sep;17(9):e280-e292.

 

The west Africa Ebola virus disease (EVD) epidemic was extraordinary in scale. Now that the epidemic has ended, it is a relevant time to examine published studies with direct relevance to clinical care and, more broadly, to examine the implications of the clinical research response ...

Last Updated: 31 Dec 1969

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Strategies in Ebola virus disease (EVD) diagnostics at the point of care.
 

Author(s): Chad T Coarsey, Nwadiuto Esiobu, Ramswamy Narayanan, Mirjana Pavlovic, Hadi Shafiee, Waseem Asghar

Journal: Crit. Rev. Microbiol.. 2017 Nov;43(6):779-798.

 

Ebola virus disease (EVD) is a devastating, highly infectious illness with a high mortality rate. The disease is endemic to regions of Central and West Africa, where there is limited laboratory infrastructure and trained staff. The recent 2014 West African EVD outbreak has been unprecedented ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Partnership for Research on Ebola VACcinations
 

Status: Recruiting

Condition Summary: Ebola Virus Disease

 

Last Updated: 16 May 2018

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International Multicenter Study of the Immunogenicity of Medicinal Product GamEvac-Combi
 

Status: Recruiting

Condition Summary: Ebola Virus Disease; Prevention

 

Last Updated: 11 May 2018

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