Ebola Virus Disease

Common Name(s)

Ebola Virus Disease

Ebola virus disease (EVD), formerly known as Ebola haemorrhagic fever, is an extremely serious and deadly disease that has historically spread through remote areas of Central and West Africa. The Ebola virus spreads first by animal-to-human, then by human-to-human contact through blood, secretions, organs, or other bodily fluids. The Ebola virus however cannot be spread through the air such as by a cough or sneeze. This means it is not as highly contagious as many other viruses. Ebola is considered highly infectious, which means if you become infected with the virus, you are likely to become very sick. Symptoms of Ebola virus include sudden onset of a high fever, weakness, vomiting, diarrhea, headaches, rash, and impaired kidney and liver functions. As the disease progresses, internal bleeding occurs as does bleeding from the eyes. Patients often experience dehydration, which is treated with fluids containing high amounts of electrolytes. Although there is currently no approved vaccine or treatment for EVD, there are several promising treatments and a possible vaccine under development. At present, early medical support to lessen the effect of the symptoms is the best way to reduce chance of death. Standard infectious disease isolation protocols can help stop the spread of EVD.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ebola Virus Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ebola Virus Disease" returned 218 free, full-text research articles on human participants. First 3 results:

The post-Ebola virus disease scourge in Nigeria: Individual levels of preparedness among physicians in the Federal Capital Territory Abuja.
 

Author(s): Adewale L Alli, Maxwell M Nwegbu, Perpetua U Ibekwe, Titus S Ibekwe

Journal: Ann Afr Med. ;15(4):171-178.

 

Ebola virus disease (EVD) is a viral hemorrhagic illness with great propensity for spread across international borders. The latest outbreak in the West African region, which involved Nigeria, was the worst among previously documented 25 outbreaks since discovery in 1976. The Nigerian ...

Last Updated: 17 Nov 2016

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Clinical presentations and outcomes of patients with Ebola virus disease in Freetown, Sierra Leone.
 

Author(s): Ying-Jie Ji, Xue-Zhang Duan, Xu-Dong Gao, Lei Li, Chen Li, Dong Ji, Wen-Gang Li, Li-Fu Wang, Yu-Hua Meng, Xiao Yang, Bin-Fang Ling, Xue-Ai Song, Mei-Lei Gu, Tao Jiang, She-Ku M Koroma, James Bangalie, Hui-Juan Duan

Journal:

 

Clinical and laboratory data were collected and analysed from patients with Ebola virus disease (EVD) in Jui Government Hospital in Freetown, Sierra Leone, where patients with EVD were received and/or treated from October 1, 2014 to March 21, 2015 during the West Africa EVD outbreak.

Last Updated: 3 Nov 2016

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A Mathematical Model with Quarantine States for the Dynamics of Ebola Virus Disease in Human Populations.
 

Author(s): Gideon A Ngwa, Miranda I Teboh-Ewungkem

Journal: Comput Math Methods Med. 2016 ;2016():9352725.

 

A deterministic ordinary differential equation model for the dynamics and spread of Ebola Virus Disease is derived and studied. The model contains quarantine and nonquarantine states and can be used to evaluate transmission both in treatment centres and in the community. Possible ...

Last Updated: 31 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ebola Virus Disease" returned 34 free, full-text review articles on human participants. First 3 results:

BCX4430 - A broad-spectrum antiviral adenosine nucleoside analog under development for the treatment of Ebola virus disease.
 

Author(s): Raymond Taylor, Pravin Kotian, Travis Warren, Rekha Panchal, Sina Bavari, Justin Julander, Sylvia Dobo, Angela Rose, Yahya El-Kattan, Brian Taubenheim, Yarlagadda Babu, William P Sheridan

Journal: J Infect Public Health. ;9(3):220-6.

 

The adenosine nucleoside analog BCX4430 is a direct-acting antiviral drug under investigation for the treatment of serious and life-threatening infections from highly pathogenic viruses, such as the Ebola virus. Cellular kinases phosphorylate BCX4430 to a triphosphate that mimics ...

Last Updated: 21 May 2016

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Clinical Management of Patients with Ebola Virus Disease in Well-resourced Settings.
 

Author(s): Yasuyuki Kato

Journal: Uirusu. 2015 ;65(1):95-104.

 

In outbreak response against Ebola virus disease (EVD), hospitals isolating the patients have a vital role to control disease transmission in communities. As of May 2015, there have been 7 suspected cases of EVD reported in Japan, but all of them were negative for ebolavirus. When ...

Last Updated: 29 Feb 2016

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Epidemiological situation of Ebola virus disease in West Africa.
 

Author(s): Yuzo Arima, Tomoe Shimada

Journal: Uirusu. 2015 ;65(1):47-54.

 

After Guinea reported an outbreak of Ebola virus disease (EVD) in March 2014, EVD spread to neighboring Sierra Leone and Liberia in West Africa. Since then, the EVD outbreak spread over a wide geographic area among these three countries, and became the largest EVD epidemic ever with ...

Last Updated: 29 Feb 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Ebola Virus Disease Survivors: Clinical and Immunologic Follow-up
 

Status: Recruiting

Condition Summary: Ebola Virus Disease

 

Last Updated: 21 Apr 2017

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Partnership for Research on Ebola VACcinations
 

Status: Recruiting

Condition Summary: Ebola Virus Disease

 

Last Updated: 21 Apr 2017

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