Ebola Virus Disease

Common Name(s)

Ebola Virus Disease

Ebola virus disease (EVD), formerly known as Ebola haemorrhagic fever, is an extremely serious and deadly disease that has historically spread through remote areas of Central and West Africa. The Ebola virus spreads first by animal-to-human, then by human-to-human contact through blood, secretions, organs, or other bodily fluids. The Ebola virus however cannot be spread through the air such as by a cough or sneeze. This means it is not as highly contagious as many other viruses. Ebola is considered highly infectious, which means if you become infected with the virus, you are likely to become very sick. Symptoms of Ebola virus include sudden onset of a high fever, weakness, vomiting, diarrhea, headaches, rash, and impaired kidney and liver functions. As the disease progresses, internal bleeding occurs as does bleeding from the eyes. Patients often experience dehydration, which is treated with fluids containing high amounts of electrolytes. Although there is currently no approved vaccine or treatment for EVD, there are several promising treatments and a possible vaccine under development. At present, early medical support to lessen the effect of the symptoms is the best way to reduce chance of death. Standard infectious disease isolation protocols can help stop the spread of EVD.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ebola Virus Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ebola Virus Disease" returned 326 free, full-text research articles on human participants. First 3 results:

Status of Ebola Virus Disease (EVD) preventive practices among Health care workers (HCWs) in Benin City: a year after disease containment in Nigeria.
 

Author(s): Amenze Oritsemofe Onowhakpor, Vincent Yakubu Adam, Oghenetega Ewomazino Sakpa, Lydia Ukamaka Ozokwelu

Journal:

 

Ebola Virus Disease (EVD) is of great public health importance. Health care workers (HCWs) in various health care facilities especially in developing countries such as Nigeria, are particularly vulnerable to the disease. It is therefore imperative that health care workers adopt the ...

Last Updated: 31 Dec 1969

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Prevention of Ebola virus disease through vaccination: where we are in 2018.
 

Author(s): Yves Lévy, Clifford Lane, Peter Piot, Abdul Habib Beavogui, Mark Kieh, Bailah Leigh, Seydou Doumbia, Eric D'Ortenzio, Claire Lévy-Marchal, Jerome Pierson, Deborah Watson-Jones, Vinh-Kim Nguyen, Heidi Larson, Julia Lysander, Christine Lacabaratz, Rodolphe Thiebaut, Augustin Augier, David Ishola, Stephen Kennedy, Geneviève Chêne, Brian Greenwood, James Neaton, Yazdan Yazdanpanah

Journal: Lancet. 2018 09;392(10149):787-790.

 

Last Updated: 31 Dec 1969

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Ebola virus disease outbreak in Guinea: what effects on prevention of mother-to-child transmission of HIV services?
 

Author(s): Niouma Nestor Leno, Alexandre Delamou, Youssouf Koita, Thierno Souleymane Diallo, Abdoulaye Kaba, Therese Delvaux, Wim Van Damme, Marie Laga

Journal:

 

An unprecedented epidemic of Ebola virus disease (EVD) affected Guinea in 2014 and 2015. It weakened the already fragile Guinean health system. This study aimed to assess the effects of the outbreak on Prevention of Mother-to-Child Transmission of HIV (PMTCT) services in 2014.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ebola Virus Disease" returned 57 free, full-text review articles on human participants. First 3 results:

A Systematic Review of Computational Drug Discovery, Development, and Repurposing for Ebola Virus Disease Treatment.
 

Author(s): James Schuler, Matthew L Hudson, Diane Schwartz, Ram Samudrala

Journal:

 

Ebola virus disease (EVD) is a deadly global public health threat, with no currently approved treatments. Traditional drug discovery and development is too expensive and inefficient to react quickly to the threat. We review published research studies that utilize computational approaches ...

Last Updated: 31 Dec 1969

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An update on ocular complications of Ebola virus disease.
 

Author(s): Jessica G Shantha, Ian Crozier, Steven Yeh

Journal: Curr Opin Ophthalmol. 2017 Nov;28(6):600-606.

 

This review provides a summary of our current understanding of the ophthalmic manifestations of Ebola virus disease (EVD), pathogenesis, treatment options and directions for future study. The individual, public health and global health implications of eye disease in EVD survivors are discussed.

Last Updated: 31 Dec 1969

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Clinical Evaluation of Ebola Virus Disease Therapeutics.
 

Author(s): Guodong Liu, Gary Wong, Shuo Su, Yuhai Bi, Frank Plummer, George F Gao, Gary Kobinger, Xiangguo Qiu

Journal: Trends Mol Med. 2017 09;23(9):820-830.

 

Ebola virus disease (EVD) was first described over 40 years ago, but no treatment has been approved for humans. The 2013-2016 EVD outbreak in West Africa has expedited the clinical evaluation of several candidate therapeutics that act through different mechanisms, but with mixed results. ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

R3470-3471-3479 Expanded Access Protocol (EAP) for Treatment of Ebola
 

Status: Available

Condition Summary: Ebola Virus Disease

 

Last Updated: 22 Jun 2018

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Partnership for Research on Ebola VACcinations
 

Status: Recruiting

Condition Summary: Ebola Virus Disease

 

Last Updated: 30 Jul 2018

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