Eclampsia

Common Name(s)

Eclampsia

Eclampsia is a very serious condition in pregnant women. Eclampsia follows a condition called preeclampsia, which is caused by high blood pressure and large amounts of protein in the urine. If not treated, preeclampsia may turn into eclampsia, in which symptoms include intense headaches, confusion, vision changes, seizures and unconsciousness that may lead to a coma. Eclampsia is dangerous for both the mother and the baby, but in the majority of cases, preeclampsia is diagnosed and treated by a physician before it develops into eclampsia. Primary treatment for eclampsia involves recognition of preeclampsia and anti-seizure medication to prevent the woman from moving into eclampsia. If this is not done, treatment of eclampsia includes immediately delivering the baby and medication to control high blood pressure and stop seizures. Eclampsia is dangerous, but recognizing symptoms of preeclampsia early is the best way to prevent it.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

Last Updated: 23 Oct 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Eclampsia" for support, advocacy or research.

H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

View Details
Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

http://www.preeclampsia.org

Last Updated: 23 Oct 2014

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General Resources

The Preeclampsia Registry

The Preeclampsia Registry is a "Living Database" bringing together those affected, their family members, and researchers to advance knowledge and discover preventions and treatments for preeclampsia, HELLP syndrome, and related hypertensive disorders

Updated 23 Oct 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Eclampsia" returned 923 free, full-text research articles on human participants. First 3 results:

First-trimester smoking cessation in pregnancy did not increase the risk of preeclampsia/eclampsia: A Murmansk County Birth Registry study.
 

Author(s): Olga A Kharkova, Andrej M Grjibovski, Alexandra Krettek, Evert Nieboer, Jon Ø Odland

Journal:

 

Although prior studies have shown that smoking reduces preeclampsia/eclampsia risk, the consequence of giving up this habit during pregnancy should be assessed. The aims of the current study were threefold: (i) describe maternal characteristics of women with preeclampsia/eclampsia; ...

Last Updated: 10 Aug 2017

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Combined screening for early and late pre-eclampsia and intrauterine growth restriction by maternal history, uterine artery Doppler, mean arterial pressure and biochemical markers.
 

Author(s): Ewelina Litwińska, Magdalena Litwińska, Przemysław Oszukowski, Krzysztof Szaflik, Piotr Kaczmarek

Journal: Adv Clin Exp Med. ;26(3):439-448.

 

Pre-eclampsia is a systemic disease connected with high maternal and fetal morbidity and mortality. Despite significant progress achieved in perinatal medicine, pre-eclampsia is still one of the most significant current problems in obstetrics.

Last Updated: 9 Aug 2017

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MiR-210 and miR-155 as potential diagnostic markers for pre-eclampsia pregnancies.
 

Author(s): Lu Gan, Zheng Liu, Ming Wei, Yulong Chen, Xiaomei Yang, Lihong Chen, Xiaomin Xiao

Journal: Medicine (Baltimore). 2017 Jul;96(28):e7515.

 

Pre-eclampsia (PE) is one of the leading causes of maternal and neonatal morbidity and mortality. In recent years, many studies have shown that microRNAs (miRNA) play important roles in the development of PE. However, the molecular pathogenesis of PE remains unknown.In the present ...

Last Updated: 12 Jul 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Eclampsia" returned 110 free, full-text review articles on human participants. First 3 results:

Pharmacogenetics in the treatment of pre-eclampsia: current findings, challenges and perspectives.
 

Author(s): Marcelo R Luizon, Ana Ct Palei, Ricardo C Cavalli, Valeria C Sandrim

Journal: Pharmacogenomics. 2017 Apr;18(6):571-583.

 

Pre-eclampsia (PE) is defined as pregnancy-induced hypertension and proteinuria, and is a major cause of maternal and perinatal morbidity and mortality. A large subgroup of pregnant women with PE is nonresponsive to antihypertensive drugs, including methyldopa, nifedipine and hydralazine. ...

Last Updated: 30 Mar 2017

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Pre-eclampsia: the Potential of GSNO Reductase Inhibitors.
 

Author(s): Thomas R Everett, Ian B Wilkinson, Christoph C Lees

Journal: Curr. Hypertens. Rep.. 2017 Mar;19(3):20.

 

Pre-eclampsia remains a leading worldwide cause of maternal death and of perinatal morbidity. There remains no definitive treatment except delivery of the fetus.

Last Updated: 8 Mar 2017

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Inter-pregnancy interval and risk of recurrent pre-eclampsia: systematic review and meta-analysis.
 

Author(s): Gabriela Cormick, Ana Pilar Betrán, Agustín Ciapponi, David R Hall, G Justus Hofmeyr,

Journal:

 

Women with a history of pre-eclampsia have a higher risk of developing pre-eclampsia in subsequent pregnancies. However, the role of the inter-pregnancy interval on this association is unclear.

Last Updated: 19 Jul 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

CA-125 and Severity of Pre-Eclampsia
 

Status: Not yet recruiting

Condition Summary: Pre-Eclampsia

 

Last Updated: 17 Mar 2016

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Use of Sildenafil Citrate in Management of Mild Pre-eclampsia
 

Status: Recruiting

Condition Summary: Pre-Eclampsia; Mild

 

Last Updated: 24 Aug 2017

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Saccadic Reaction Time and Preterm Pre-eclampsia
 

Status: Recruiting

Condition Summary: Pre-eclampsia

 

Last Updated: 3 Apr 2017

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