Emphysema

Common Name(s)

Emphysema

Emphysema is a chronic (long term) lung condition. It is a form of COPD (chronic obstructive pulmonary disease). The air you breathe goes into your lungs through airways. At the end of our airways in our lungs are tiny air sacs (alveoli). It is the air sacs that become damaged over time in emphysema. As the air sacs are damaged, their inner walls break down causing the sac to become larger. Larger sacs absorb less oxygen than those of normal size. The damage also causes difficulty breathing or shortness of breath. The damaged air sacs cannot be replaced.

Symptoms of emphysema may not occur until years after the damage to the air sacs begins. Symptoms may include shortness of breath, decreased mental alertness, and blue or gray fingertips or lips. Risk of developing emphysema is increased if there has been long-term exposure to airborne irritants including tobacco smoke, marijuana smoke, air pollution, and manufacturing fumes. A less common form of emphysema is caused by the lack of a special type of protein (alpha-1-antitrypsin). This type of emphysema is usually caused by a mutation or change in your genes and therefore will run in families.

To diagnosis emphysema, a physician may perform a variety of tests, which may include a chest x-ray to rule out other causes, lab tests to examine oxygen in the blood stream, and lung function tests to measure air flow in and out of the lungs. Treatment to relieve symptoms and slow the progression of the disease may include medications, therapy, or surgery. See a doctor if you have had unexplained shortness of breath for several months, particularly if it is getting worse or interfering with your daily activities. If you have been diagnosed with emphysema, talk with your doctor or specialist about the most current treatment options. Support groups are also a good source of information and support.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Emphysema" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Emphysema" returned 1236 free, full-text research articles on human participants. First 3 results:

Normalized emphysema scores on low dose CT: Validation as an imaging biomarker for mortality.
 

Author(s): Leticia Gallardo-Estrella, Esther Pompe, Pim A de Jong, Colin Jacobs, Eva M van Rikxoort, Mathias Prokop, Clara I Sánchez, Bram van Ginneken

Journal:

 

The purpose of this study is to develop a computed tomography (CT) biomarker of emphysema that is robust across reconstruction settings, and evaluate its ability to predict mortality in patients at high risk for lung cancer. Data included baseline CT scans acquired between August ...

Last Updated: 31 Dec 1969

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[Endoscopic lung volume reduction in advanced pulmonary emphysema: initial experience in Chile].
 

Author(s): Sebastián Fernández-Bussy, Gonzalo Labarca, Iván Caviedes, Hiren J Mehta, Michael Jantz, Adnan Majid

Journal: Rev Med Chil. 2017 May;145(5):667-672.

 

Chronic obstructive pulmonary disease (COPD) has no curative treatment, and in moderate to advanced stages, functional parameters and quality of life are affected. Lung volume reduction improves respiratory parameters and quality of life of these patients. Endoscopic lung volume reduction ...

Last Updated: 31 Dec 1969

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Intralobar pulmonary sequestration displayed as localized emphysema on computed tomography image.
 

Author(s): Weibo Qi, Junjie Zhao, Guping Shi, Fan Yang

Journal:

 

Pulmonary sequestration is a relatively rare condition in which a systemic artery supplies blood to an abnormal lung tissue and the normal connection with the bronchial tree is absent. It can be displayed as various signs on the computed tomography image, but emphysema is extremely rare.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Emphysema" returned 100 free, full-text review articles on human participants. First 3 results:

A rare case of cavitary lung cancer complicated with mycotic pneumonia and bullous emphysema: A case report and review of the literature.
 

Author(s): Cun-Tao Lu, Rui-Mei Zhang, Heng Wang, Feng-Wei Kong, Wen-Bin Wu, Long-Bo Gong, Miao Zhang

Journal: Medicine (Baltimore). 2017 Nov;96(47):e8927.

 

The accurate diagnosis and staging of cavitary lung cancer is challenging but essential for the choice of therapy; therefore, the differential diagnosis of cystic pulmonary lesions needs to be elucidated.

Last Updated: 31 Dec 1969

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Telomerase and the Genetics of Emphysema Susceptibility. Implications for Pathogenesis Paradigms and Patient Care.
 

Author(s): Susan E Stanley, Samantha J Merck, Mary Armanios

Journal: Ann Am Thorac Soc. 2016 Dec;13(Supplement_5):S447-S451.

 

In the past five decades, alpha-1 antitrypsin deficiency has been the only known genetic cause of emphysema, yet it explains the genetics in only 1-2% of severe cases. Recently, mutations in telomerase genes were found to induce susceptibility to young-onset, severe, and familial ...

Last Updated: 31 Dec 1969

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Lung Cancer in Combined Pulmonary Fibrosis and Emphysema: A Systematic Review and Meta-Analysis.
 

Author(s): Hyun Jung Koo, Kyung-Hyun Do, Jung Bok Lee, Sania Alblushi, Sang Min Lee

Journal:

 

Patients with combined pulmonary fibrosis and emphysema (CPFE) have been suggested to have an increased risk of lung cancer. We conducted a systematic review of all published data and performed a meta-analysis to define the characteristics of lung cancer that develops in CPFE.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of PneumRx Endobronchial Coil System in Treatment of Subjects With Severe Emphysema
 

Status: Not yet recruiting

Condition Summary: Emphysema

 

Last Updated: 27 Nov 2017

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Losartan Effects on Emphysema Progression
 

Status: Recruiting

Condition Summary: Emphysema

 

Last Updated: 13 Feb 2018

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