Empty Sella Syndrome

Common Name(s)

Empty Sella Syndrome

Empty sella syndrome (ESS) is a condition that involves the sella turcica, a bony structure at the base of the brain that protects the pituitary gland. There is a primary and secondary form of the condition. The primary form occurs when a structural defect above the pituitary gland increases pressure in the sella turcica and causes the gland to flatten. The secondary form occurs when the pituitary gland is damaged due to injury, a tumor, surgery or radiation therapy. Some people with ESS have no symptoms. People with secondary ESS may have symptoms of decreased pituitary function such as absence of menstruation, infertility, fatigue, and intolerance to stress and infection. In children, ESS may be associated with early onset of puberty, growth hormone deficiency, pituitary tumors, or pituitary gland dysfunction. Treatment focuses on the symptoms present in each person.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Empty Sella Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Empty Sella Syndrome" returned 31 free, full-text research articles on human participants. First 3 results:

Macroprolactinemia and Empty Sella Syndrome.
 

Author(s): Ach Taieb, Kacem Njah Maha, Yosra Hasni El Abed, Amel Maaroufi Beizig, Molka Chaieb Chadli, Koussay Ach

Journal:

 

Macroprolactinemia is a polymeric form of prolactin-release, causing mildly symptomatic clinical pictures. The former can be isolated or associated with other causes of hyperprolactinemia. The association with an empty sella syndrome is rare. We report a case of a female patient discovered ...

Last Updated: 31 Dec 1969

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Primary Empty Sella Syndrome Presenting With Severe Hyponatremia And Minimal Salt Wasting.
 

Author(s): Ishma Aijazi, Fadil Mustafa Abdullah Al Shama, Sara Hussein Adam Mukhtar

Journal: J Ayub Med Coll Abbottabad. ;28(3):605-608.

 

A 41 year old Jordanian gentleman known case of osteogenesis imperfecta presented with vomiting, decreased oral intake followed by confusion. At presentation he was found to have signs of hypogonadism with severe hyponatremia. The hyponatremia responded to intravenous steroid replacement ...

Last Updated: 31 Dec 1969

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A Case Report of Late Onset Mania Caused by Hyponatremia in a Patient With Empty Sella Syndrome.
 

Author(s): Chung-Hao Yang, Yu-Chen Lin, Po-Han Chou, Hung-Chieh Chen, Chin-Hong Chan

Journal: Medicine (Baltimore). 2016 Feb;95(6):e2629.

 

Recurrent manic-like episodes can be induced by hyponatremia possibly due to empty sella syndrome. In the present case, the patient was proven to have syndrome of inappropriate antidiuretic hormone (SIADH) secretion with manic symptoms that resolved after the normalization of the ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Empty Sella Syndrome" returned 1 free, full-text review articles on human participants. First 3 results:

A case of hypothalamic panhypopituitarism with empty sella syndrome: case report and review of the literature.
 

Author(s): Hisako Komada, Masaaki Yamamoto, Saki Okubo, Kanto Nagai, Keiji Iida, Takehiro Nakamura, Yushi Hirota, Kazuhiko Sakaguchi, Masato Kasuga, Yutaka Takahashi

Journal: Endocr. J.. 2009 ;56(4):585-9.

 

Empty sella syndrome is frequently accompanied with pituitary dysfunction. Most of the patients with empty sella syndrome demonstrate primary pituitary or stalk dysfunction and few cases show hypothalamic dysfunction. A 71-year-old man manifested appetite loss, nausea and vomiting ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.