Endocarditis

Common Name(s)

Endocarditis

Endocarditis is condition affecting the heart lining, heart valves, or blood vessels. Endocarditis can be caused by bacterial or fungal infection (infective endocarditis) or by blood clots that form on the heart valves or lining (non-infective endocarditis or non-bacterial thrombotic endocarditis (NBTE)). In cases of infective endocarditis, the infected area becomes inflamed and immune cells can be seen in the affected area. In cases of non-infective endocarditis, there is no inflammation of the heart lining or valves.

The young and the old are at increased risk of experiencing endocarditis. Those with cancer, diabetes, HIV/AIDS, or a weakened immune system are also at an increased risk. Those with certain blood clotting conditions are at increased risk for NBTE. Symptoms of infective endocarditis can include fever, chills, fatigue, and achiness. Symptoms of both infective and non-infective endocarditis can include coughing, shortness of breath, weight loss, muscle and joint pain, a heart murmur, and small spots of blood under the skin or fingernails. It is important to seek treatment if you experience these symptoms. If untreated, endocarditis can be fatal.

Endocarditis can often be diagnosed using a physical examination, an ultrasound of the heart (echocardiogram), testing of heart rhythm with an EKG, blood cultures to test for bacteria, and an X-ray of the chest. Treatment for infective endocarditis includes antibiotics. Treatment for NBTE usually includes anticoagulants to decrease the likelihood of blood clots and to help break up any existing clots. If you or a loved one has been diagnosed with endocarditis, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Endocarditis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Endocarditis" returned 2812 free, full-text research articles on human participants. First 3 results:

Infective Endocarditis Associated with Atopic Dermatitis.
 

Author(s): Shigeaki Aoyagi, Takeshi Oda, Kumiko Wada, Eiji Nakamura, Tomokazu Kosuga, Hiroshi Yasunaga

Journal: Int Heart J. 2018 Mar;59(2):420-423.

 

We report a case of aortic valve infective endocarditis (IE) in a 24-year-old man with atopic dermatitis (AD). He had a history of balloon valvuloplasty for a stenotic bicuspid aortic valve, and had dental caries but no invasive dental procedure before the onset of IE. On admission, ...

Last Updated: 31 Dec 1969

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Loeffler endocarditis as a rare cause of heart failure with preserved ejection fraction: A case report and review of literature.
 

Author(s): Ming Gao, Weihua Zhang, Waiou Zhao, Ling Qin, Fei Pei, Yang Zheng

Journal: Medicine (Baltimore). 2018 Mar;97(11):e0079.

 

Hypereosinophilic syndrome (HES) is a rare disease characterized by hypereosinophilia and its ensuing organ damage. Cardiac involvement is divided into 3 chronological stages: an acute necrotic stage; a thrombus formation stage; and a fibrotic stage. Infiltration of the myocardium ...

Last Updated: 31 Dec 1969

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Surgical interventions of isolated active mitral valve endocarditis: Predisposing factors and impact of neurological insults on final outcome.
 

Author(s): Hsiu-An Lee, Chun-Yu Lin, Yung-Chang Chen, Shao-Wei Chen, Yu-Yun Nan, Kuo-Sheng Liu, Meng-Yu Wu, Yu-Sheng Chang, Jaw-Ji Chu, Pyng-Jing Lin, Feng-Chun Tsai

Journal: Medicine (Baltimore). 2018 Mar;97(11):e0054.

 

The feasibility and durability of mitral valve (MV) repair in active infective endocarditis (IE) has been reported, but proper management of perioperative neurological complications and surgical timing remains uncertain and may crucially affect the outcome.In this single-center retrospective ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Endocarditis" returned 285 free, full-text review articles on human participants. First 3 results:

Probiotics and infective endocarditis in patients with hereditary hemorrhagic telangiectasia: a clinical case and a review of the literature.
 

Author(s): Evangelo Boumis, Alessandro Capone, Vincenzo Galati, Carolina Venditti, Nicola Petrosillo

Journal:

 

In the last decades, probiotics have been widely used as food supplements because of their putative beneficial health effects. They are generally considered safe but rare reports of serious infections caused by bacteria included in the definition of probiotics raise concerns on their ...

Last Updated: 31 Dec 1969

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Successful management of a complicated clinical crisis: A patient with left-sided endocarditis and secondary hemophagocytic lymphohistiocytosis: a rare case report and literature review.
 

Author(s): Peipei Xu, Hui Zeng, Min Zhou, Jian Ouyang, Bing Chen, Qiguo Zhang

Journal: Medicine (Baltimore). 2017 Dec;96(51):e9451.

 

Hemophagocytic lymphohistiocytosis (HLH) secondary to methicillin-resistant Staphylococcus epidermidis (MRSE)-related left-sided infectious endocarditis had never been reported before. In the last decade, daptomycin, a novel lipopeptide antibiotic, showed its excellent role in anti-Gram-positive ...

Last Updated: 31 Dec 1969

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[Lactococcus garvieae endocarditis in a patient undergoing chronic hemodialysis. First case report in Chile and review of the literature].
 

Author(s): Rene Clavero, Juanita Escobar, Sergio Ramos-Avasola, Lorenzo Merello, Francisco Álvarez

Journal: Rev Chilena Infectol. 2017 Aug;34(4):397-403.

 

Reports of Lactococcus garvieae infections in humans are scarce, and only one of them in a patient under-going hemodialysis. We report the first case of Lactococcus garvieae infection in Chile, presenting as an infective endocarditis, ultimately fatal, in a patient with uncomplicated ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Management of Infectious Endocarditis as Part of a Multidisciplinary Consensus Meeting
 

Status: Recruiting

Condition Summary: Endocarditis

 

Last Updated: 9 Feb 2018

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Last Updated: 13 Mar 2018

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Last Updated: 25 Jan 2018

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