Endocarditis

Common Name(s)

Endocarditis

Endocarditis is condition affecting the heart lining, heart valves, or blood vessels. Endocarditis can be caused by bacterial or fungal infection (infective endocarditis) or by blood clots that form on the heart valves or lining (non-infective endocarditis or non-bacterial thrombotic endocarditis (NBTE)). In cases of infective endocarditis, the infected area becomes inflamed and immune cells can be seen in the affected area. In cases of non-infective endocarditis, there is no inflammation of the heart lining or valves.

The young and the old are at increased risk of experiencing endocarditis. Those with cancer, diabetes, HIV/AIDS, or a weakened immune system are also at an increased risk. Those with certain blood clotting conditions are at increased risk for NBTE. Symptoms of infective endocarditis can include fever, chills, fatigue, and achiness. Symptoms of both infective and non-infective endocarditis can include coughing, shortness of breath, weight loss, muscle and joint pain, a heart murmur, and small spots of blood under the skin or fingernails. It is important to seek treatment if you experience these symptoms. If untreated, endocarditis can be fatal.

Endocarditis can often be diagnosed using a physical examination, an ultrasound of the heart (echocardiogram), testing of heart rhythm with an EKG, blood cultures to test for bacteria, and an X-ray of the chest. Treatment for infective endocarditis includes antibiotics. Treatment for NBTE usually includes anticoagulants to decrease the likelihood of blood clots and to help break up any existing clots. If you or a loved one has been diagnosed with endocarditis, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Endocarditis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Endocarditis" returned 2766 free, full-text research articles on human participants. First 3 results:

Emphysematous endocarditis caused by AmpC beta-lactamase-producing Escherichia coli: A case report.
 

Author(s): Chung-Jong Kim, Jeong-Eun Yi, Yookyung Kim, Hee Jung Choi

Journal: Medicine (Baltimore). 2018 Feb;97(6):e9620.

 

Infective endocarditis (IE) is a life-threatening disease, mostly caused by gram-positive bacteria. Gram-negative bacteria were identified as a causative organism in relatively small number of cases. Although, antibiotic-resistant Escherichia coli is common cause of gram-negative ...

Last Updated: 31 Dec 1969

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Successful treatment of an acute infective endocarditis secondary to fish bone penetrating into left atrium caused by Granulicatella adiacens and Candida albicans: A case report.
 

Author(s): Ya Ling Tong, Ting Ting Qu, Jia Xu, Nai Yun Chen, Mei Fang Yang

Journal: Medicine (Baltimore). 2017 Dec;96(51):e9185.

 

Infective endocarditis caused by a foreign body of the upper digestive tract is rare. We report a rare case of Granulicatella adiacens and Candida albicans coinfection acute endocarditis combined with systematic embolization caused by a fish bone from the esophagus penetrating into the left atrium.

Last Updated: 31 Dec 1969

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Fever of unknown origin and splenomegaly: A case report of blood culture negative endocarditis.
 

Author(s): Maria Livia Burzo, Mariangela Antonelli, Giovanni Pecorini, Angela M R Favuzzi, Raffaele Landolfi, Andrea Flex

Journal: Medicine (Baltimore). 2017 Dec;96(50):e9197.

 

Fever of unknown origin (FUO) can be determined by different conditions among which infectious diseases represent the main cause.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Endocarditis" returned 280 free, full-text review articles on human participants. First 3 results:

Successful management of a complicated clinical crisis: A patient with left-sided endocarditis and secondary hemophagocytic lymphohistiocytosis: a rare case report and literature review.
 

Author(s): Peipei Xu, Hui Zeng, Min Zhou, Jian Ouyang, Bing Chen, Qiguo Zhang

Journal: Medicine (Baltimore). 2017 Dec;96(51):e9451.

 

Hemophagocytic lymphohistiocytosis (HLH) secondary to methicillin-resistant Staphylococcus epidermidis (MRSE)-related left-sided infectious endocarditis had never been reported before. In the last decade, daptomycin, a novel lipopeptide antibiotic, showed its excellent role in anti-Gram-positive ...

Last Updated: 31 Dec 1969

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[Lactococcus garvieae endocarditis in a patient undergoing chronic hemodialysis. First case report in Chile and review of the literature].
 

Author(s): Rene Clavero, Juanita Escobar, Sergio Ramos-Avasola, Lorenzo Merello, Francisco Álvarez

Journal: Rev Chilena Infectol. 2017 Aug;34(4):397-403.

 

Reports of Lactococcus garvieae infections in humans are scarce, and only one of them in a patient under-going hemodialysis. We report the first case of Lactococcus garvieae infection in Chile, presenting as an infective endocarditis, ultimately fatal, in a patient with uncomplicated ...

Last Updated: 31 Dec 1969

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The prognosis of infective endocarditis treated with biological valves versus mechanical valves: A meta-analysis.
 

Author(s): Ende Tao, Li Wan, WenJun Wang, YunLong Luo, JinFu Zeng, Xia Wu

Journal:

 

Surgery remains the primary form of treatment for infective endocarditis (IE). However, it is not clear what type of prosthetic valve provides a better prognosis. We conducted a meta-analysis to compare the prognosis of infective endocarditis treated with biological valves to cases ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Management of Infectious Endocarditis as Part of a Multidisciplinary Consensus Meeting
 

Status: Recruiting

Condition Summary: Endocarditis

 

Last Updated: 9 Feb 2018

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Last Updated: 25 Jan 2018

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Clinical Metagenomics of Infective Endocarditis
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 22 Jun 2017

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