Enterovirus

Common Name(s)

Enterovirus

Enteroviruses are a group of small viruses that usually infect the gastrointestinal tract or respiratory system initially, but can spread throughout the body. The virus can cause no symptoms until years later. Enteroviruses can be classified into two groups, polioviruses and non-polio enteroviruses. Although polioviruses are almost completely prevented through vaccination, non-polio enteroviruses can be the cause of a wide variety of diseases and symptoms. While many enteroviral infections cause mild cold or flu-like symptoms, fever or a rash (hand-foot-and-mouth disease) or no symptoms at all, other enteroviral infections may sometimes infect the heart (myocarditis), brain (encephalitis), central nervous system (meningitis) or or respiratory system (causing problems with breathing). Actual symptoms depend on which enterovirus is causing the infection. Enteroviral infections spread very much like the common cold, such as through a person’s saliva or any contact with contaminated surface or object. Infants and children are usually at the highest risk for enterovirus infections, but adults with weak immune systems may be infected as well. A doctor most often diagnoses an enterovirus infection through a physical examination and observed symptoms. Blood tests are available for certain types of enterovirus and may be used for confirmation. There are currently no effective anti-vrial medications for enteroviral infections. Treatment depends on the symptoms and may include supportive care such as bedrest, pain relievers and fever reducers. If the infection is severe, hospitalization may be needed. The best way to stop the spread of enteroviral infections is to wash your hands carefullly before eating or touching your mouth or eyes, especially if you are caring for someone who is sick. Individuals should also avoid kissing, hugging, sharing cups or eating utensils with people who are sick. If you or a family member have symptoms which seem to be get

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Following organizations serve the condition "Enterovirus" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Enterovirus" returned 855 free, full-text research articles on human participants. First 3 results:

Enterovirus and Parechovirus Surveillance - United States, 2014-2016.
 

Author(s): Glen R Abedi, John T Watson, W Allan Nix, M Steven Oberste, Susan I Gerber

Journal:

 

Infections caused by enteroviruses (EV) and parechoviruses (PeV), members of the Picornaviridae family, are associated with various clinical manifestations, including hand, foot, and mouth disease; respiratory illness; myocarditis; meningitis; and sepsis; and can result in death. ...

Last Updated: 31 Dec 1969

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Rapid and Accurate Sequencing of Enterovirus Genomes Using MinION Nanopore Sequencer.
 

Author(s): Ji Wang, Yue Hua Ke, Yong Zhang, Ke Qiang Huang, Lei Wang, Xin Xin Shen, Xiao Ping Dong, Wen Bo Xu, Xue Jun Ma

Journal: Biomed. Environ. Sci.. 2017 Oct;30(10):718-726.

 

Knowledge of an enterovirus genome sequence is very important in epidemiological investigation to identify transmission patterns and ascertain the extent of an outbreak. The MinION sequencer is increasingly used to sequence various viral pathogens in many clinical situations because ...

Last Updated: 31 Dec 1969

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Suppression of the toll-like receptor 7-dependent type I interferon production pathway by autophagy resulting from enterovirus 71 and coxsackievirus A16 infections facilitates their replication.
 

Author(s): Jie Song, Yajie Hu, Jiaqi Li, Huiwen Zheng, Jingjing Wang, Lei Guo, Haijng Shi, Longding Liu

Journal: Arch. Virol.. 2018 Jan;163(1):135-144.

 

Toll-like receptors (TLRs) act as molecular sentinels, detecting invading viral pathogens and triggering host innate immune responses, including autophagy. However, many viruses have evolved a series of strategies to manipulate autophagy for their own benefit. Enterovirus 71 (EV71) ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Enterovirus" returned 52 free, full-text review articles on human participants. First 3 results:

Direct-acting antivirals and host-targeting strategies to combat enterovirus infections.
 

Author(s): Lisa Bauer, Heyrhyoung Lyoo, Hilde M van der Schaar, Jeroen Rpm Strating, Frank Jm van Kuppeveld

Journal: Curr Opin Virol. 2017 06;24():1-8.

 

Enteroviruses (e.g., poliovirus, enterovirus-A71, coxsackievirus, enterovirus-D68, rhinovirus) include many human pathogens causative of various mild and more severe diseases, especially in young children. Unfortunately, antiviral drugs to treat enterovirus infections have not been ...

Last Updated: 31 Dec 1969

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Impact of Enterovirus Testing on Resource Use in Febrile Young Infants: A Systematic Review.
 

Author(s): Sowdhamini S Wallace, Michelle A Lopez, A Chantal Caviness

Journal: Hosp Pediatr. 2017 02;7(2):96-102.

 

Enterovirus infection commonly causes fever in infants aged 0 to 90 days and, without testing, is difficult to differentiate from serious bacterial infection.

Last Updated: 31 Dec 1969

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The Current Status of the Disease Caused by Enterovirus 71 Infections: Epidemiology, Pathogenesis, Molecular Epidemiology, and Vaccine Development.
 

Author(s): Ping-Chin Chang, Shou-Chien Chen, Kow-Tong Chen

Journal:

 

Enterovirus 71 (EV71) infections have a major public health impact in the Asia-Pacific region. We reviewed the epidemiology, pathogenesis, and molecular epidemiology of EV71 infection as well as EV71 vaccine development. Previous studies were found using the search terms "enterovirus ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety Study of Enterovirus 71 Vaccine in Children Aged 6-35 Months Old
 

Status: Not yet recruiting

Condition Summary: Enterovirus 71 Vaccine

 

Last Updated: 17 Jun 2016

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Clinical Study on Combined Immune Effect of EV71 Inactivated Vaccine
 

Status: Recruiting

Condition Summary: Enterovirus 71 Inactivated Vaccine; HFMD

 

Last Updated: 25 Apr 2018

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Last Updated: 6 Sep 2016

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