Enterovirus

Common Name(s)

Enterovirus

Enteroviruses are a group of small viruses that usually infect the gastrointestinal tract or respiratory system initially, but can spread throughout the body. The virus can cause no symptoms until years later. Enteroviruses can be classified into two groups, polioviruses and non-polio enteroviruses. Although polioviruses are almost completely prevented through vaccination, non-polio enteroviruses can be the cause of a wide variety of diseases and symptoms. While many enteroviral infections cause mild cold or flu-like symptoms, fever or a rash (hand-foot-and-mouth disease) or no symptoms at all, other enteroviral infections may sometimes infect the heart (myocarditis), brain (encephalitis), central nervous system (meningitis) or or respiratory system (causing problems with breathing). Actual symptoms depend on which enterovirus is causing the infection. Enteroviral infections spread very much like the common cold, such as through a person’s saliva or any contact with contaminated surface or object. Infants and children are usually at the highest risk for enterovirus infections, but adults with weak immune systems may be infected as well. A doctor most often diagnoses an enterovirus infection through a physical examination and observed symptoms. Blood tests are available for certain types of enterovirus and may be used for confirmation. There are currently no effective anti-vrial medications for enteroviral infections. Treatment depends on the symptoms and may include supportive care such as bedrest, pain relievers and fever reducers. If the infection is severe, hospitalization may be needed. The best way to stop the spread of enteroviral infections is to wash your hands carefullly before eating or touching your mouth or eyes, especially if you are caring for someone who is sick. Individuals should also avoid kissing, hugging, sharing cups or eating utensils with people who are sick. If you or a family member have symptoms which seem to be get

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Enterovirus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Enterovirus" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Enterovirus" returned 847 free, full-text research articles on human participants. First 3 results:

Rapid and Accurate Sequencing of Enterovirus Genomes Using MinION Nanopore Sequencer.
 

Author(s): Ji Wang, Yue Hua Ke, Yong Zhang, Ke Qiang Huang, Lei Wang, Xin Xin Shen, Xiao Ping Dong, Wen Bo Xu, Xue Jun Ma

Journal: Biomed. Environ. Sci.. 2017 Oct;30(10):718-726.

 

Knowledge of an enterovirus genome sequence is very important in epidemiological investigation to identify transmission patterns and ascertain the extent of an outbreak. The MinION sequencer is increasingly used to sequence various viral pathogens in many clinical situations because ...

Last Updated: 31 Dec 1969

Go To URL
Suppression of the toll-like receptor 7-dependent type I interferon production pathway by autophagy resulting from enterovirus 71 and coxsackievirus A16 infections facilitates their replication.
 

Author(s): Jie Song, Yajie Hu, Jiaqi Li, Huiwen Zheng, Jingjing Wang, Lei Guo, Haijng Shi, Longding Liu

Journal: Arch. Virol.. 2018 Jan;163(1):135-144.

 

Toll-like receptors (TLRs) act as molecular sentinels, detecting invading viral pathogens and triggering host innate immune responses, including autophagy. However, many viruses have evolved a series of strategies to manipulate autophagy for their own benefit. Enterovirus 71 (EV71) ...

Last Updated: 31 Dec 1969

Go To URL
Enterovirus 71 protease 2Apro and 3Cpro differentially inhibit the cellular endoplasmic reticulum-associated degradation (ERAD) pathway via distinct mechanisms, and enterovirus 71 hijacks ERAD component p97 to promote its replication.
 

Author(s): Tao Wang, Bei Wang, He Huang, Chongyang Zhang, Yuanmei Zhu, Bin Pei, Chaofei Cheng, Lei Sun, Jianwei Wang, Qi Jin, Zhendong Zhao

Journal:

 

Endoplasmic reticulum-associated degradation (ERAD) is an important function for cellular homeostasis. The mechanism of how picornavirus infection interferes with ERAD remains unclear. In this study, we demonstrated that enterovirus 71 (EV71) infection significantly inhibits cellular ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Enterovirus" returned 51 free, full-text review articles on human participants. First 3 results:

Impact of Enterovirus Testing on Resource Use in Febrile Young Infants: A Systematic Review.
 

Author(s): Sowdhamini S Wallace, Michelle A Lopez, A Chantal Caviness

Journal: Hosp Pediatr. 2017 02;7(2):96-102.

 

Enterovirus infection commonly causes fever in infants aged 0 to 90 days and, without testing, is difficult to differentiate from serious bacterial infection.

Last Updated: 31 Dec 1969

Go To URL
The Current Status of the Disease Caused by Enterovirus 71 Infections: Epidemiology, Pathogenesis, Molecular Epidemiology, and Vaccine Development.
 

Author(s): Ping-Chin Chang, Shou-Chien Chen, Kow-Tong Chen

Journal:

 

Enterovirus 71 (EV71) infections have a major public health impact in the Asia-Pacific region. We reviewed the epidemiology, pathogenesis, and molecular epidemiology of EV71 infection as well as EV71 vaccine development. Previous studies were found using the search terms "enterovirus ...

Last Updated: 31 Dec 1969

Go To URL
EV-A71 vaccine licensure: a first step for multivalent enterovirus vaccine to control HFMD and other severe diseases.
 

Author(s): Qunying Mao, Yiping Wang, Lianlian Bian, Miao Xu, Zhenglun Liang

Journal:

 

Enteroviruses (EVs) are the most common viral agents in humans. Although most infections are mild or asymptomatic, there is a wide spectrum of clinical manifestations that may be caused by EV infections with varying degrees of severity. Among these viruses, EV-A71 and coxsackievirus ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety Study of Enterovirus 71 Vaccine in Children Aged 6-35 Months Old
 

Status: Not yet recruiting

Condition Summary: Enterovirus 71 Vaccine

 

Last Updated: 17 Jun 2016

Go to URL

Last Updated: 6 Sep 2016

Go to URL
Phase IV Clinical Trial, Immunogenicity and Safety of EV71 Vaccine
 

Status: Recruiting

Condition Summary: Hand, Foot and Mouth Disease

 

Last Updated: 8 Sep 2017

Go to URL