Extragonadal Germ Cell Tumor

Common Name(s)

Extragonadal Germ Cell Tumor

Extragonadal germ cell tumors are rare tumors found in the reproductive organs (testicles in males, ovaries in females), that travel to other parts of the body outside of the ovary or testicle (e.g. brain, chest, abdomen, or tailbone). It is most commonly found in young males, age 20 or older. On risk factor for this condition is having Klinefelter syndrome. Symptoms of extragonadal cell tumors are varied and include chest pain, breathing problems, coughing, fever, headache, or trouble seeing or moving the eyes. Treatment depends on whether the size of the tumor, location of tumor, blood levels, the way the tumor responds to initial treatment, whether the tumor has spread, and whether the cancer has just been diagnosed or has come back. Treatment options include radiation therapy, chemotherapy, surgery, or possible clinical trials.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Extragonadal Germ Cell Tumor" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Extragonadal Germ Cell Tumor" returned 17 free, full-text research articles on human participants. First 3 results:

[A case of metachronal testicular tumor eight years after medical treatment of extragonadal germ cell tumor].
 

Author(s): Makoto Tanio, Yoshitaka Aoki, Hisato Kobayashi, Satoshi Yokoi, Hideaki Ito, Nobuyuki Oyama, Hironobu Akino, Osamu Yokoyama

Journal: Hinyokika Kiyo. 2015 Apr;61(4):173-6.

 

A 22-year-old man was admitted to our hospital complaining of a left cervical mass. Computed tomography (CT) showed multiple enlarged lymph nodes at the left cervical vein and para-aortic areas. Histological examination of a biopsy indicated an embryonal carcinoma. The levels of human ...

Last Updated: 31 Dec 1969

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Extragonadal germ cell tumor with the "burned-out" phenomenon presented a multiple retroperitoneal masses: a case report.
 

Author(s): Salih Budak, Orcun Celik, Hakan Turk, Tufan Suelozgen, Yusuf Ozlem Ilbey

Journal: Asian J. Androl.. ;17(1):163-4.

 

Last Updated: 31 Dec 1969

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Mixed extragonadal germ cell tumor arising from the prostate: a rare combination.
 

Author(s): Shu-Guang Liu, Bin Lei, Xue-Nong Li, Xiao-Dong Chen, Shuang Wang, Lin Zheng, Hai-Li Zhu, Pei-Xin Lin, Hong Shen

Journal: Asian J. Androl.. ;16(4):645-6.

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Extragonadal Germ Cell Tumor" returned 4 free, full-text review articles on human participants. First 3 results:

[A case of metachronous testicular tumor developing seven years after complete remission of retroperitoneal extragonadal germ cell tumor].
 

Author(s): Norihiko Kawamura, Keisuke Yamamoto, Iwao Yoshioka, Hiroshi Kiuchi, Sanehiro Momohara, Yasuhiro Matsuoka, Naotsugu Ichimaru, Norio Nonomura, Akihiko Okuyama, Tatsuya Kinoshita

Journal: Hinyokika Kiyo. 2009 Oct;55(10):635-8.

 

A 26-year-old man was admitted to our hospital with a chief complaint of left cervical lymphadenopathy. He was diagnosed as having seminoma by needle biopsy. Computed tomography revealed an aorto-caval retroperitoneal tumor. Levels of lactic deydrogenase, human beta-chorionic gonadotropin, ...

Last Updated: 31 Dec 1969

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Metachronous testicular tumor developing eight years after retroperitoneal extragonadal germ cell tumor.
 

Author(s): Yuta Yamada, Kyouichi Tomita, Tetsuya Fujimura, Hiroaki Nishimatsu, Takumi Takeuchi, Tadaichi Kitamura

Journal: Int. J. Urol.. 2008 Mar;15(3):267-9.

 

A 30 year-old man was admitted to our hospital with a chief complaint of left flank pain. Computed tomography revealed a retroperitoneal tumor. Levels of lactic dehydrogenase, human beta-chorionic gonadotropin, alpha-fetoprotein, DUPAN-2 and carbohydrate antigen 19-9 were elevated. ...

Last Updated: 31 Dec 1969

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[The result of VIP chemotherapy as an induction therapy in 6 patients with non-seminomatous extragonadal germ cell tumor].
 

Author(s): Mizuaki Sakura, Tetsurou Tsukamoto, Junji Yonese, Masayuki Nakaishi, Yuhei Ohkubo, Takuya Maezawa, Keita Takimoto, Iwao Fukui, Ken Nakagawa, Sakae Okumura, Yuichi Ishikawa, Nozomu Aoki

Journal: Nippon Hinyokika Gakkai Zasshi. 2004 Mar;95(3):634-7.

 

We treated 6 patients with non-seminomatous extragonadal germ cell tumor (NSEGCT) by VP-16 + ifosfamide + cisplatin (VIP) chemotherapy as an induction therapy to investigate the effectiveness and safety. Primary lesions were located at the mediastinum in 4 patients and the retroperitoneum ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

PHASE II TRIAL OF THE CYCLIN-DEPEDENT KINASE INHIBITOR PD 0332991 IN PATIENTS WITH CANCER
 

Status: Recruiting

Condition Summary: Adult Solid Tumor; Adenocarcinoma of the Colon; Adenocarcinoma of the Rectum; Adult Central Nervous System Germ Cell Tumor; Adult Teratoma; Benign Teratoma; Estrogen Receptor-negative Breast Cancer; Estrogen Receptor-positive Breast Cancer; Familial Testicular Germ Cell Tumor; HER2-negative Breast Cancer; HER2-positive Breast Cancer; Male Breast Cancer; Ovarian Immature Teratoma; Ovarian Mature Teratoma; Ovarian Monodermal and Highly Specialized Teratoma; Progesterone Receptor-negative Breast Cancer; Progesterone Receptor-positive Breast Cancer; Recurrent Breast Cancer; Recurrent Colon Cancer; Recurrent Extragonadal Germ Cell Tumor; Recurrent Extragonadal Non-seminomatous Germ Cell Tumor; Recurrent Extragonadal Seminoma; Recurrent Malignant Testicular Germ Cell Tumor; Recurrent Melanoma; Recurrent Ovarian Germ Cell Tumor; Recurrent Rectal Cancer; Stage III Extragonadal Non-seminomatous Germ Cell Tumor; Stage III Extragonadal Seminoma; Stage III Malignant Testicular Germ Cell Tumor; Stage III Ovarian Germ Cell Tumor; Stage IV Breast Cancer; Stage IV Colon Cancer; Stage IV Extragonadal Non-seminomatous Germ Cell Tumor; Stage IV Extragonadal Seminoma; Stage IV Melanoma; Stage IV Ovarian Germ Cell Tumor; Stage IV Rectal Cancer; Testicular Immature Teratoma; Testicular Mature Teratoma

 

Last Updated: 24 Aug 2016

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Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors
 

Status: Recruiting

Condition Summary: Childhood Germ Cell Tumor; Ovarian Cancer; Teratoma

 

Last Updated: 29 Nov 2017

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Collecting and Storing Tissue From Young Patients With Cancer
 

Status: Recruiting

Condition Summary: Cancer

 

Last Updated: 27 Nov 2017

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