Fallopian Tube Cancer

Common Name(s)

Fallopian tube cancer is a very rare form of cancer with only 1,500 to 2,000 cases reported each year in the United States. However, a number of cancers start in other parts of the body and spread to the fallopian tubes, called secondary fallopian tube cancers. Some symptoms include abnormal vaginal bleeding, abnormal vaginal discharge, abdominal pain, and feeling a mass in the abdomen (belly) or pelvis. A female pelvic exam can assist in the diagnosis of this condition by evaluating the size and shape of the uterus, vagina, ovaries, fallopian tubes, bladder and rectum. A blood test can also be performed to check the levels of a certain protein called CA125, which may be used to diagnose fallopian tube cancer. Treatment usually involves surgery and chemotherapy, depending on age, desire to have children, and the type and stage of the tumor.

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Advocacy and Support Organizations

Condition Specific Organizations

Following organizations serve the condition "Fallopian Tube Cancer" for support, advocacy or research.

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Advocacy and Support Organizations

Condition Specific Organizations

Following organizations serve the condition "Fallopian Tube Cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

General Support Organizations

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Finding the right clinical trial for Fallopian Tube Cancer can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Fallopian Tube Cancer" returned 74 free, full-text research articles on human participants. First 3 results:

Characterization of MicroRNA-200 pathway in ovarian cancer and serous intraepithelial carcinoma of fallopian tube.

Author(s): Junzheng Yang, Yilan Zhou, Shu-Kay Ng, Kuan-Chun Huang, Xiaoyan Ni, Pui-Wah Choi, Kathleen Hasselblatt, Michael G Muto, William R Welch, Ross S Berkowitz, Shu-Wing Ng

Journal:

Ovarian cancer is the leading cause of death among gynecologic diseases in Western countries. We have previously identified a miR-200-E-cadherin axis that plays an important role in ovarian inclusion cyst formation and tumor invasion. The purpose of this study was to determine if ...

Last Updated: 31 Dec 1969

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Progesterone Prevents High-Grade Serous Ovarian Cancer by Inducing Necroptosis of p53-Defective Fallopian Tube Epithelial Cells.

Author(s): Na-Yiyuan Wu, Hsuan-Shun Huang, Tung Hui Chao, Hsien Ming Chou, Chao Fang, Chong-Zhen Qin, Chueh-Yu Lin, Tang-Yuan Chu, Hong Hao Zhou

Journal: Cell Rep. 2017 03;18(11):2557-2565.

High-grade serous ovarian carcinoma (HGSOC) originates mainly from the fallopian tube (FT) epithelium and always carries early TP53 mutations. We previously reported that tumors initiate in the FT fimbria epithelium because of apoptotic failure and the expansion of cells with DNA ...

Last Updated: 31 Dec 1969

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Activin A stimulates migration of the fallopian tube epithelium, an origin of high-grade serous ovarian cancer, through non-canonical signaling.

Author(s): Matthew Dean, David A Davis, Joanna E Burdette

Journal: Cancer Lett.. 2017 04;391():114-124.

Factors that stimulate the migration of fallopian tube epithelial (FTE)-derived high-grade serous ovarian cancer (HGSOC) to the ovary are poorly elucidated. This study characterized the effect of the ovarian hormone, activin A, on normal FTE and HGSOC. Activin A and TGFβ1 induced ...

Last Updated: 31 Dec 1969

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PubMed Article Results at NCBI: 74 article(s)

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Fallopian Tube Cancer" returned 7 free, full-text review articles on human participants. First 3 results:

Data set for reporting of ovary, fallopian tube and primary peritoneal carcinoma: recommendations from the International Collaboration on Cancer Reporting (ICCR).

Author(s): W Glenn McCluggage, Meagan J Judge, Blaise A Clarke, Ben Davidson, C Blake Gilks, Harry Hollema, Jonathan A Ledermann, Xavier Matias-Guiu, Yoshiki Mikami, Colin J R Stewart, Russell Vang, Lynn Hirschowitz,

Journal: Mod. Pathol.. 2015 Aug;28(8):1101-22.

A comprehensive pathological report is essential for optimal patient management, cancer staging and prognostication. In many countries, proforma reports are used but these vary in their content. The International Collaboration on Cancer Reporting (ICCR) is an alliance formed by the ...

Last Updated: 31 Dec 1969

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FIGO's staging classification for cancer of the ovary, fallopian tube, and peritoneum: abridged republication.

Author(s): Jaime Prat,

Journal: J Gynecol Oncol. 2015 Apr;26(2):87-9.

Last Updated: 31 Dec 1969

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Precursors of ovarian cancer in the fallopian tube: serous tubal intraepithelial carcinoma--an update.

Author(s): Felix Zeppernick, Ivo Meinhold-Heerlein, Ie-Ming Shih

Journal: J. Obstet. Gynaecol. Res.. 2015 Jan;41(1):6-11.

Ovarian tumors comprise a wide variety of entities. The largest group, epithelial ovarian carcinoma, can be classified into two main groups, type I and type II tumors. Recent advances in the understanding of ovarian cancer development have resulted in the finding of 'serous tubal ...

Last Updated: 31 Dec 1969

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PubMed Review Results at NCBI: 7 review(s)

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Symptoms, Diagnosis, and Treatment

This information is provided by Genetics Home Reference.

Full Results at Genetics Home Reference: 715 matches

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Trial of Carboplatin-Paclitaxel-Bevacizumab vs Carboplatin-Paclitaxel-Bevacizumab-Rucaparib vs Carboplatin-Paclitaxel-Rucaparib in Patients With Advanced (Stage III B-C-IV) Ovarian, Primary Peritoneal and Fallopian Tube Cancer.

Status: Recruiting

Condition Summary: Advanced (Stage IIIB-C-IV) Ovarian, Primary Peritoneal and Fallopian Tube Cancer

Last Updated: 9 May 2018

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Paclitaxel + Carboplatin With AVB-S6-500 in Women With Stage III or IV Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer Receiving Neoadjuvant Chemotherapy

Status: Not yet recruiting

Condition Summary: Epithelial Ovarian Cancer; Primary Peritoneal Carcinoma; Fallopian Tube Cancer

Last Updated: 23 Jul 2018

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Intraperitoneal Infusion of Autologous Monocytes With Sylatron (Peginterferon Alfa-2b) and Actimmune (Interferon Gamma-1b) in Women With Recurrent or Refractory Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer

Status: Recruiting

Condition Summary: Fallopian Tube Cancer; Ovarian Cancer; Primary Peritoneal Cancer

Last Updated: 24 Jul 2018

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According to ClinicalTrials.gov there are currently 146 additional "open" studies for "Fallopian Tube Cancer" (open studies are recruiting volunteers) and 650 "Fallopian Tube Cancer" studies with "all" status. Visit ClinicalTrials.gov now to view them. Or alternatively, consider TrialsFinder for assistance:

Relief is when you and the right researcher find each other
Finding the right clinical trial for Fallopian Tube Cancer can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.

Learn More