Familial Hypersensitivity Pneumonitis

Common Name(s)

Familial Hypersensitivity Pneumonitis

Hypersensitivity Pneumonitis (HP) is a disease that occurs when the lungs become inflamed from breathing in foreign substances like molds, dusts, and chemicals. Most people who breathe in these substances don’t develop HP. However, those that do may develop one of two types: acute (short-term) and chronic (ongoing). Acute HP leads to chills, body aches, coughing, and chest tightness within 2-9 hours of exposure. After hours or days of no contact with the inflammatory substance, symptoms usually go away. If symptoms don't go away, it may lead to chronic HP. Symptoms of chronic HP occur over the course of months, leading to a worsening cough, shortness of breath with physical activity, fatigue, and weight loss. Severe HP may cause a widening and rounding of the tips of the fingers. Symptoms may continue or worsen even after avoiding the original substance and can lead to long-term lung damage. In cases of chronic or severe HP, doctors may prescribe anti-inflammatory drugs to decrease swelling in the lungs and prevent further damage.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Familial Hypersensitivity Pneumonitis" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Familial Hypersensitivity Pneumonitis" returned 1 free, full-text research articles on human participants. First 3 results:

A familial history of pulmonary fibrosis in patients with chronic hypersensitivity pneumonitis.
 

Author(s): Tsukasa Okamoto, Yasunari Miyazaki, Makoto Tomita, Meiyo Tamaoka, Naohiko Inase

Journal: Respiration. 2013 ;85(5):384-90.

 

Hypersensitivity pneumonitis (HP) is an immunologically mediated lung disease induced by the inhalation of a variety of antigens. Patients with chronic HP often have a family history of pulmonary fibrosis. This strongly suggests that both genetic and environmental factors play an ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Familial Hypersensitivity Pneumonitis" returned 2 free, full-text review articles on human participants. First 3 results:

Familial Summer-type Hypersensitivity Pneumonitis: A Review of 25 Families and 50 Cases in Japan.
 

Author(s): Nobuhiro Asai, Norihiro Kaneko, Yoshihiro Ohkuni, Masahiro Aoshima, Yasutaka Kawamura

Journal: Intern. Med.. 2016 ;55(3):279-83.

 

Summer-type hypersensitivity pneumonitis (SHP) is the most common form of pneumonitis in Japan; it accounts for 74% of all cases. It has been reported that 19.5-23.8% of SHP cases occur in families who live in the same house. We present our SHP cases and review 50 familial cases in ...

Last Updated: 31 Dec 1969

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Familial summer-type hypersensitivity pneumonitis in Japan: two case reports and review of the literature.
 

Author(s): Akira Nakajima, Takeshi Saraya, Takeshi Mori, Reiko Ikeda, Takashi Sugita, Takayasu Watanabe, Masachika Fujiwara, Hajime Takizawa, Hajime Goto

Journal:

 

Hypersensitivity pneumonitis is defined as an allergic lung disease that occurs in response to inhalation of fungal antigens, bacterial antigens, chemicals, dusts, or animal proteins. The incidence of summer-type hypersensitivity pneumonitis is higher in the summer season, especially ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.