Familial Hypertrophic Cardiomyopathy
Common Name(s)
Familial Hypertrophic Cardiomyopathy
Advocacy and Support Organizations
Condition Specific Organizations
Following organizations serve the condition "Familial Hypertrophic Cardiomyopathy" for support, advocacy or research.
How do you compare to others with this condition?
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Advocacy and Support Organizations
Condition Specific Organizations
Following organizations serve the condition "Familial Hypertrophic Cardiomyopathy" for support, advocacy or research.
Recommended Apps
Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.
Finding the right clinical trial for Familial Hypertrophic Cardiomyopathy can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.
Scientific Literature
Articles from the PubMed Database
Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Familial Hypertrophic Cardiomyopathy" returned 131 free, full-text research articles on human participants.
First 3 results:
Journal: Turk Kardiyol Dern Ars. 2017 Jul;45(5):450-453.
Familial hypertrophic cardiomyopathy is a genetically heterogeneous disease with variable clinical features that is inherited as autosomal dominant with variable penetrance. Recent developments in genetics of hereditary cardiomyopathy have not only enlightened many points about pathogenesis, ...
Journal: Stem Cell Res. 2017 04;20():76-79.
Induced pluripotent stem cells (iPSCs) were generated from peripheral blood mononuclear cells (PBMCs) obtained from a 62-year-old female with familial hypertrophic cardiomyopathy (HCM). PBMCs were reprogrammed to a pluripotent state following transfection with non-integrative episomal ...
Journal:
Fabry disease is caused by mutations in the α-galactosidase A (GLA) gene, which is located in X-chromosome coding for the lysosomal enzyme of GLA. Among many gene mutations, E66Q mutation is under discussion for its pathogenicity because there is no clinical report showing pathological ...
To view other free, full-text articles on human participants, please click on the link below.
Reviews from the PubMed Database
Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Familial Hypertrophic Cardiomyopathy" returned 7 free, full-text review articles on human participants.
First 3 results:
Journal: J R Soc Interface. 2011 Nov;8(64):1550-61.
Familial hypertrophic cardiomyopathy (FHC) is an inherited disorder affecting roughly one in 500 people. Its hallmark is abnormal thickening of the ventricular wall, leading to serious complications that include heart failure and sudden cardiac death. Treatment is complicated by variation ...
Journal: Kardiol Pol. 2009 Jul;67(7):774-80; discussion 781.
A family with hypertrophic cardiomyopathy (HCM) (15-year-old boy, his 17-year-old sister and 45-year-old father) is described. The first sign of HCM was cardiac arrest (CA) due to ventricular fibrillation (VF) in a boy. A few months later sister of proband had the episode of CA due ...
Journal: Cell Res.. 2004 Apr;14(2):95-110.
The muscle protein myosin binding protein C (MyBPC) is a large multi-domain protein whose role in the sarcomere is complex and not yet fully understood. Mutations in MyBPC are strongly associated with the heart disease familial hypertrophic cardiomyopathy (FHC) and these experiments ...
To view other free, full-text review articles on human participants, please click on the link below.
Symptoms, Diagnosis, and Treatment
https://ghr.nlm.nih.gov/gene/TNNI3
https://ghr.nlm.nih.gov/condition/familial-dilated-cardiomyopathy
https://ghr.nlm.nih.gov/gene/TNNT2
https://ghr.nlm.nih.gov/condition/familial-restrictive-cardiomyopathy
https://ghr.nlm.nih.gov/gene/LAMP2
https://ghr.nlm.nih.gov/gene/ACTC1
https://ghr.nlm.nih.gov/gene/CSRP3
https://ghr.nlm.nih.gov/gene/CALR3
https://ghr.nlm.nih.gov/gene/MYOZ2
https://ghr.nlm.nih.gov/gene/MYBPC3
https://ghr.nlm.nih.gov/gene/PLN
https://ghr.nlm.nih.gov/gene/MYL2
https://ghr.nlm.nih.gov/gene/MYL3
https://ghr.nlm.nih.gov/gene/SLC25A4
https://ghr.nlm.nih.gov/gene/TPM1
https://ghr.nlm.nih.gov/gene/NDUFV2
https://ghr.nlm.nih.gov/gene/NDUFB9
https://ghr.nlm.nih.gov/gene/TTN
https://ghr.nlm.nih.gov/gene/MYH7
There are currently no related results available in GeneReviews.
There are currently no related results available in Genetic Testing Registry.
Clinical Trial Information This information is provided by ClinicalTrials.gov
There are currently no open clinical trials for this condition.
Finding the right clinical trial for Familial Hypertrophic Cardiomyopathy can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.