Familial Renal Cell Carcinoma

Common Name(s)

Familial Renal Cell Carcinoma

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Familial Renal Cell Carcinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Familial Renal Cell Carcinoma" returned 9 free, full-text research articles on human participants. First 3 results:

A novel germline mutation in BAP1 predisposes to familial clear-cell renal cell carcinoma.
 

Author(s): Megan N Farley, Laura S Schmidt, Jessica L Mester, Samuel Pena-Llopis, Andrea Pavia-Jimenez, Alana Christie, Cathy D Vocke, Christopher J Ricketts, James Peterson, Lindsay Middelton, Lisa Kinch, Nick Grishin, Maria J Merino, Adam R Metwalli, Chao Xing, Xian-Jin Xie, Patricia L M Dahia, Charis Eng, W Marston Linehan, James Brugarolas

Journal: Mol. Cancer Res.. 2013 Sep;11(9):1061-1071.

 

Renal cell carcinoma (RCC) clusters in some families. Familial RCC arises from mutations in several genes, including the von Hippel-Lindau (VHL) tumor suppressor, which is also mutated in sporadic RCC. However, a significant percentage of familial RCC remains unexplained. Recently, ...

Last Updated: 31 Dec 1969

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Analysis of germline variants in CDH1, IGFBP3, MMP1, MMP3, STK15 and VEGF in familial and sporadic renal cell carcinoma.
 

Author(s): Christopher Ricketts, Maurice P Zeegers, Jan Lubinski, Eamonn R Maher

Journal:

 

The investigation of rare familial forms of kidney cancer has provided important insights into the biology of sporadic renal cell carcinoma (RCC). In particular, the identification of the von Hippel Lindau (VHL) familial cancer syndrome gene (VHL) provided the basis for the discovery ...

Last Updated: 31 Dec 1969

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Familial non-VHL clear cell (conventional) renal cell carcinoma: clinical features, segregation analysis, and mutation analysis of FLCN.
 

Author(s): Emma R Woodward, Christopher Ricketts, Pip Killick, Sophie Gad, M R Morris, Fred Kavalier, Shirley V Hodgson, Sophie Giraud, Brigitte Bressac-de Paillerets, Cyril Chapman, Bernard Escudier, Farida Latif, St├ęphane Richard, Eamonn R Maher

Journal: Clin. Cancer Res.. 2008 Sep;14(18):5925-30.

 

Familial renal cell carcinoma (RCC) is genetically heterogeneous. The most common histopathologic subtype of sporadic and familial RCC is clear cell (cRCC) and von Hippel-Lindau (VHL) disease is the most common cause of inherited cRCC. Familial cRCC may also be associated with chromosome ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Familial Renal Cell Carcinoma" returned 1 free, full-text review articles on human participants. First 3 results:

Familial renal cell carcinoma: review of recent molecular genetics.
 

Author(s): M Yao, T Shuin

Journal: Int. J. Urol.. 1995 May;2(2):61-70.

 

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Ascertainment of Families for Genetic Studies of Familial Lymphoproliferative Disorders
 

Status: Recruiting

Condition Summary: Lymphoma; Leukemia; Multiple Myeloma; Colon Cancer; Renal Cancer

 

Last Updated: 24 Apr 2018

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Integrated Cancer Repository for Cancer Research
 

Status: Recruiting

Condition Summary: Pancreatic Cancer; Thyroid Cancer; Lung Cancer; Esophageal Cancer; Thymus Cancer; Colon Cancer; Rectal Cancer; GIST; Anal Cancer; Bile Duct Cancer; Duodenal Cancer; Gallbladder Cancer; Gastric Cancer; Liver Cancer; Small Intestine Cancer; Peritoneal Surface Malignancies; Familial Adenomatous Polyposis; Lynch Syndrome; Bladder Cancer; Kidney Cancer; Penile Cancer; Prostate Cancer; Testicular Cancer; Ureter Cancer; Urethral Cancer; Hypopharyngeal Cancer; Laryngeal Cancer; Lip Cancer; Oral Cavity Cancer; Nasopharyngeal Cancer; Oropharyngeal Cancer; Paranasal Sinus Cancer; Nasal Cavity Cancer; Salivary Gland Cancer; Skin Cancer; CNS Tumor; CNS Cancer; Mesothelioma; Breastcancer; Leukemia; Melanoma; Sarcoma; Unknown Primary Tumor; Multiple Myeloma; Ovarian Cancer; Endometrial Cancer; Vaginal Cancer

 

Last Updated: 5 May 2017

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The Molecular Predisposition to Hereditary Nonpolyposis Colon Cancer (HNPCC)
 

Status: Recruiting

Condition Summary: Bladder Cancer; Colorectal Cancer; Endometrial Cancer; Kidney Cancer; Skin Cancer; Uterus Cancer

 

Last Updated: 12 Jan 2018

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