Febrile seizures

Common Name(s)

Febrile seizures

Febrile seizures are seizures that affect children and are usually triggered by high fever, often due to an infection. During a febrile seizure a child may rapidly shake, twitch, moan, roll their eyes, or lose consciousness. Febrile seizures most often occur in children between 6 months and 5 years of age. However, the highest risk period for a febrile seizure is between 12 months and 18 months of age. Children with a family history of febrile seizures are at an increased risk for these seizures. Fortunately, febrile seizures are typically harmless and do not cause any other health problems. They are usually seen as the brain’s response to a high fever. There are two forms of febrile seizures: simple and complex. Simple febrile seizures are more common and usually last between a few seconds to 15 minutes. Complex febrile seizures may last more than 15 minutes, happen more than once in the span of 24 hours, and occur on one side of the child’s body.

Doctors can diagnose febrile seizures by using a test called an electroencephalogram (EEG). This test checks the brain for unusual electrical activity often seen with a seizure. To find the cause of the febrile seizure, doctors may run blood tests, urine tests, or perform a spinal tap. A spinal tap is a procedure used to remove cerebrospinal fluid, fluid that surrounds the brain and spinal cord to protect them from injury, by inserting a small needle in the lower back. Treatment typically depends on the root cause and severity of the seizure and can range from treating the infection (antibiotics) to treating the seizures (antiepileptic medication). Talk with your child’s doctor or specialist to decide which treatment options are best for your child. Support groups are also good resources for support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Febrile seizures" for support, advocacy or research.

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Pediatric Brain Foundation

Pediatric Brain Foundation's Mission is Three-fold: 1. Expedite scientific research to find treatments and cures for ALL of the more than 14 million children, in the U.S. alone, living with some form of neurological disorder 2. Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology 3. Educate the public and public officials on the critical importance of funding pediatric neurological research

Last Updated: 22 Apr 2015

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Febrile seizures" for support, advocacy or research.

Logo
Pediatric Brain Foundation

Pediatric Brain Foundation's Mission is Three-fold: 1. Expedite scientific research to find treatments and cures for ALL of the more than 14 million children, in the U.S. alone, living with some form of neurological disorder 2. Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology 3. Educate the public and public officials on the critical importance of funding pediatric neurological research

http://www.pediatricbrainfoundation.org

Last Updated: 22 Apr 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Febrile seizures" returned 181 free, full-text research articles on human participants. First 3 results:

[Association between SCN1A rs3812718 polymorphism and generalized epilepsy with febrile seizures plus].
 

Author(s): Qi-Ling Ma, Bo Wang, Guang-Fu Chen, Jian-Lin Huang, Yun Li, De-Zhi Cao, Rong-Tian Liu

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2018 Feb;20(2):130-133.

 

To investigate the association between SCN1A rs3812718 polymorphism and generalized epilepsy with febrile seizures plus (GEFS+), and to provide potential molecular targets for the diagnosis and treatment of GEFS+.

Last Updated: 31 Dec 1969

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Analysis of plasma multiplex cytokines and increased level of IL-10 and IL-1Ra cytokines in febrile seizures.
 

Author(s): Kyungmin Kim, Byung Ok Kwak, Aram Kwon, Jongseok Ha, Soo-Jin Kim, Sun Whan Bae, Jae Sung Son, Soo-Nyung Kim, Ran Lee

Journal:

 

Febrile seizures are the most common form of childhood seizures. Fever generation involves many cytokines, including both pro- and anti-inflammatory cytokines. Some of these cytokines also induce febrile seizures. We compared cytokine production in children with a fever alone (healthy ...

Last Updated: 31 Dec 1969

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The assessment of laboratory parameters in children with fever and febrile seizures.
 

Author(s): Krystyna Gontko-Romanowska, Zbigniew Żaba, Paweł Panieński, Barbara Steinborn, Michał Szemień, Magdalena Łukasik-Głębocka, Krystian Ratajczak, Jacek Górny

Journal:

 

The aim of the research paper was to assess selected laboratory results in children with fever without seizures and febrile seizure.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Febrile seizures" returned 31 free, full-text review articles on human participants. First 3 results:

Complex febrile seizures-A systematic review.
 

Author(s): Harry Whelan, Matthew Harmelink, Erica Chou, Delphin Sallowm, Nadir Khan, Rachit Patil, Kumar Sannagowdara, Jun Ho Kim, Wei Liang Chen, Suad Khalil, Ivana Bajic, Aliyah Keval, Donald Greydanus

Journal: Dis Mon. 2017 Jan;63(1):5-23.

 

Last Updated: 31 Dec 1969

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Generation of Febrile Seizures and Subsequent Epileptogenesis.
 

Author(s): Bo Feng, Zhong Chen

Journal: Neurosci Bull. 2016 Oct;32(5):481-92.

 

Febrile seizures (FSs) occur commonly in children aged from 6 months to 5 years. Complex (repetitive or prolonged) FSs, but not simple FSs, can lead to permanent brain modification. Human infants and immature rodents that have experienced complex FSs have a high risk of subsequent ...

Last Updated: 31 Dec 1969

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Febrile seizures and genetic epilepsy with febrile seizures plus (GEFS+).
 

Author(s): Peter Camfield, Carol Camfield

Journal: Epileptic Disord. 2015 Jun;17(2):124-33.

 

To review the literature about febrile seizures and GEFS plus with special emphasis on management and outcome. Selected literature review. Febrile seizures are the most common convulsive event in humans, occurring in 2-6% of the population. The aetiology is complex with strong evidence ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Anthropogenetic Variability in the Group of Individuals With Febrile Seizures
 

Status: Recruiting

Condition Summary: Febrile Seizure

 

Last Updated: 22 Mar 2018

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Comparison Between Melatonin and Diazepam for Prevention of Recurrent Simple Febrile Seizures
 

Status: Recruiting

Condition Summary: Febrile Seizures

 

Last Updated: 13 Aug 2018

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