Fetal Hydantoin Syndrome

Common Name(s)

Fetal Hydantoin Syndrome

Fetal hydantoin syndrome is a disorder that is caused by exposure of a fetus to phenytoin, a drug commonly prescribed for epilepsy. Not all infants exposed to phenytoin will be affected with the disorder. Symptoms in affected individuals may include abnormalities of the skull and facial features, growth deficiencies, underdeveloped nails of the fingers and toes, and/or mild developmental delays. Other findings occasionally associated with this syndrome include cleft lip and palate, having an abnormally small head (microcephaly) and brain malformations with more significant developmental delays. Treatment may include surgery for cleft lip and palate and special education and related services for children with learning delays. Other treatment is symptomatic and supportive.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fetal Hydantoin Syndrome" for support, advocacy or research.

Organisation for Anti-Convulsant Syndromes

To support those with an anti-convulsant syndromes and their families. To generate a greater awareness fo this condition. We also promote research, to further the understanding of this condition

Last Updated: 21 Nov 2014

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fetal Hydantoin Syndrome" for support, advocacy or research.

Organisation for Anti-Convulsant Syndromes

To support those with an anti-convulsant syndromes and their families. To generate a greater awareness fo this condition. We also promote research, to further the understanding of this condition

http://www.oacscharity.org

Last Updated: 21 Nov 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Fetal Hydantoin Syndrome" returned 4 free, full-text research articles on human participants. First 3 results:

Fetal hydantoin syndrome: A case report.
 

Author(s): A Singh, H P Bhatia, A Mohan, N Sharma

Journal: J Indian Soc Pedod Prev Dent. ;34(1):92-5.

 

Fetal hydantoin syndrome (FHS) is a spectrum of defects caused to the developing fetus by exposure to the teratogenic effects of antiepileptic drug (AED) phenytoin during pregnancy. Its clinical manifestations include limb abnormalities, ocular defects, central nervous system anomalies, ...

Last Updated: 31 Dec 1969

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Transposition of the great arteries and hypocalcemia in a patient with fetal hydantoin syndrome.
 

Author(s): Mrugeshkumar K Shah, Eva Morava, William Gill, Michael R Marble

Journal: J Perinatol. 2002 Jan;22(1):89-90.

 

We report a patient with fetal hydantoin syndrome (FHS) with associated d-transposition of the great arteries (d-TGA) and persistent hypocalcemia. d-TGA and hypocalcemia have each been individually reported once in association with FHS, but these patients were also prenatally exposed ...

Last Updated: 31 Dec 1969

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Prenatal prediction of risk of the fetal hydantoin syndrome.
 

Author(s): B A Buehler, D Bick, D Delimont

Journal: N. Engl. J. Med.. 1993 Nov;329(22):1660-1.

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Fetal Hydantoin Syndrome" returned 0 free, full-text review articles on human participants.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.