Fibromuscular Dysplasia

Common Name(s)

Fibromuscular Dysplasia

Fibromuscular dysplasia (FMD) is the abnormal development or growth of cells in the walls of arteries that can cause the vessels to narrow or bulge. The carotid arteries, which pass through the neck and supply blood to the brain, are commonly affected. Arteries within the brain and kidneys can also be affected. Narrowing and enlarging of arteries can block or reduce blood flow to the brain, causing a stroke. Some patients experience no symptoms of the disease while others may have high blood pressure, dizziness or vertigo, chronic headache, intracranial aneurysm, ringing in the ears, weakness or numbness in the face, neck pain, or changes in vision. FMD is most often seen in people age 25 to 50 years and affects women more often than men. More than one family member may be affected by the disease. The cause of FMD is unknown. Treatment is based on the arteries affected and the progression and severity of the disease.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fibromuscular Dysplasia" for support, advocacy or research.

Fibromuscular Dysplasia Society of America

The Fibromuscular Dysplasia Society of America is a voluntary health organization dedicated to improving the lives of those afflicted with Fibromuscular Dysplasia by raising awareness and developing funds to promote research towards new medical treatments and diagnostic tools.

Last Updated: 15 Jan 2014

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FMD Chat

FMD Chat is an international nonprofit organization dedicated to supporting those affected by fibromuscular dysplasia including patients, family members, caregivers, and healthcare professionals.

Last Updated: 7 May 2014

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Midwest Women's Vascular Advocates

Our mission is to support and educate women affected by Fibromsucular Dysplasia and non-inflammatory vascular disease.

Last Updated: 20 Jan 2011

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fibromuscular Dysplasia" for support, advocacy or research.

Fibromuscular Dysplasia Society of America

The Fibromuscular Dysplasia Society of America is a voluntary health organization dedicated to improving the lives of those afflicted with Fibromuscular Dysplasia by raising awareness and developing funds to promote research towards new medical treatments and diagnostic tools.

http://www.fmdsa.org

Last Updated: 15 Jan 2014

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FMD Chat

FMD Chat is an international nonprofit organization dedicated to supporting those affected by fibromuscular dysplasia including patients, family members, caregivers, and healthcare professionals.

http://www.fmdchat.org

Last Updated: 7 May 2014

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Midwest Women's Vascular Advocates

Our mission is to support and educate women affected by Fibromsucular Dysplasia and non-inflammatory vascular disease.

www.mwva.org

Last Updated: 20 Jan 2011

View Details

 

General Support Organizations

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General Resources

FMD Chat Readings & Resources

Learn more about fibromuscular dysplasia, systems impacted by the disease, general health, advance planning, caregiving, and international rare disease organizations.

Uploaded By: FMD Chat

Updated 13 Dec 2012

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RareConnect's International FMD Community

Connect with patients around the world via RareConnect and the fibromuscular dysplasia community that FMD Chat helped develop. Translation services are available so that users may better share information.

Uploaded By: FMD Chat

Updated 13 Dec 2012

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Patient Support Information

A list of resources for patients diagnosed with FMD.

Updated 25 Mar 2013

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FMD Clinics

A list of FMD Clinics in the United States

Updated 25 Mar 2013

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FMD Patient Stories

A list of patients stories including children , men, multiple family members and pregnancy and FMD.

Updated 25 Mar 2013

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Centers participating in the FMD Patient Registry

A List of 12 centers participating in the FMD Patient Registry.

Updated 25 Mar 2013

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Educational Video's

Video's on fibromuscular dysplasia

Updated 25 Mar 2013

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FMD Web Chat Transcripts

Web chat transcripts. Dr Heather Gornik of the Cleveland Clinic and Pam Mace Executive Director of FMDSA answer patient questions

Updated 15 Jan 2014

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FMD Emergency Wallet Card/PT Toolbox

FMD emergency wallet card for patients, medication card and letter for your physician

Updated 15 Jan 2014

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FMD Research

A list of research studies for patients who are interested in participating

Updated 15 Jan 2014

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Smart Patients

Smart Patients is available to anyone who has access to the internet, and its community has a medically-influenced approach to information sharing. FMD Chat's Smart Patients community is for patients and caregivers.

Uploaded By: FMD Chat

Updated 7 May 2014

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Updated 7 May 2014

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Blogs

FMDSA Facebook Page

Where articles and current news is posted daily.

Updated 8 Oct 2012

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FMDSA Inspire Support group

On line support group community for patients with Fibromuscular Dysplasia (FMD)

Updated 25 Mar 2013

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Insurance Issues

FMD Chat NeedyMeds Prescription Drug Discount Card

The drug discount card is not an insurance plan, but provides patients with discounted rates on prescriptions. When this card is presented with a valid prescription to a pharmacist, up to an 80 percent discount may be provided.

Uploaded by Advocacy Organization: FMD Chat

Updated 13 Dec 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Fibromuscular Dysplasia" returned 142 free, full-text research articles on human participants. First 3 results:

Fibromuscular Dysplasia of the Brachial Artery.
 

Author(s): Mistyann-Blue Miller, Demetrio R Flores

Journal: N. Engl. J. Med.. 2017 01;376(2):e2.

 

Last Updated: 11 Jan 2017

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Loss-of-Function Mutations in YY1AP1 Lead to Grange Syndrome and a Fibromuscular Dysplasia-Like Vascular Disease.
 

Author(s): Dong-Chuan Guo, Xue-Yan Duan, Ellen S Regalado, Lauren Mellor-Crummey, Callie S Kwartler, Dong Kim, Kenneth Lieberman, Bert B A de Vries, Rolph Pfundt, Albert Schinzel, Dieter Kotzot, Xuetong Shen, Min-Lee Yang, , Michael J Bamshad, Deborah A Nickerson, Heather L Gornik, Santhi K Ganesh, Alan C Braverman, Dorothy K Grange, Dianna M Milewicz

Journal: Am. J. Hum. Genet.. 2017 Jan;100(1):21-30.

 

Fibromuscular dysplasia (FMD) is a heterogeneous group of non-atherosclerotic and non-inflammatory arterial diseases that primarily involves the renal and cerebrovascular arteries. Grange syndrome is an autosomal-recessive condition characterized by severe and early-onset vascular ...

Last Updated: 12 Dec 2016

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PHACTR1 Is a Genetic Susceptibility Locus for Fibromuscular Dysplasia Supporting Its Complex Genetic Pattern of Inheritance.
 

Author(s): Soto Romuald Kiando, Nathan R Tucker, Luis-Jaime Castro-Vega, Alexander Katz, Valentina D'Escamard, Cyrielle Tréard, Daniel Fraher, Juliette Albuisson, Daniella Kadian-Dodov, Zi Ye, Erin Austin, Min-Lee Yang, Kristina Hunker, Cristina Barlassina, Daniele Cusi, Pilar Galan, Jean-Philippe Empana, Xavier Jouven, Anne-Paule Gimenez-Roqueplo, Patrick Bruneval, Esther Soo Hyun Kim, Jeffrey W Olin, Heather L Gornik, Michel Azizi, Pierre-François Plouin, Patrick T Ellinor, Iftikhar J Kullo, David J Milan, Santhi K Ganesh, Pierre Boutouyrie, Jason C Kovacic, Xavier Jeunemaitre, Nabila Bouatia-Naji

Journal:

 

Fibromuscular dysplasia (FMD) is a nonatherosclerotic vascular disease leading to stenosis, dissection and aneurysm affecting mainly the renal and cerebrovascular arteries. FMD is often an underdiagnosed cause of hypertension and stroke, has higher prevalence in females (~80%) but ...

Last Updated: 28 Oct 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Fibromuscular Dysplasia" returned 15 free, full-text review articles on human participants. First 3 results:

Renal Fibromuscular Dysplasia: A Not So Common Entity of Secondary Hypertension.
 

Author(s): Elias A Sanidas, Maria Seferou, Dimitris P Papadopoulos, Anastasios Makris, Nora A Viniou, Vasiliki Chantziara, Vasiliki Cennimata, Vasilios Papademetriou

Journal: J Clin Hypertens (Greenwich). 2016 Mar;18(3):240-6.

 

Fibromuscular dysplasia is a rare noninflammatory vascular disease characterized by nonatheroslerotic stenosis predominantly seen in young women, whereas the majority of cases involve the renal arteries causing secondary hypertension. Most noninvasive screening tests are not quite ...

Last Updated: 13 Mar 2016

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Recent developments in the understanding and management of fibromuscular dysplasia.
 

Author(s): Sarah C O'Connor, Heather L Gornik

Journal: J Am Heart Assoc. 2014 Dec;3(6):e001259.

 

Last Updated: 27 Dec 2014

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Coronary artery manifestations of fibromuscular dysplasia.
 

Author(s): Katherine C Michelis, Jeffrey W Olin, Daniella Kadian-Dodov, Valentina d'Escamard, Jason C Kovacic

Journal: J. Am. Coll. Cardiol.. 2014 Sep;64(10):1033-46.

 

Fibromuscular dysplasia (FMD) involving the coronary arteries is an uncommon but important condition that can present as acute coronary syndrome, left ventricular dysfunction, or potentially sudden cardiac death. Although the classic angiographic "string of beads" that may be observed ...

Last Updated: 5 Sep 2014

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Assessment of Renal Artery Fibromuscular Dysplasia: From Diagnosis to Treatment
 

Status: Recruiting

Condition Summary: Renal Artery Fibromuscular Dysplasia

 

Last Updated: 6 Jul 2016

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Defining the Basis of Fibromuscular Dysplasia (FMD)
 

Status: Recruiting

Condition Summary: Fibromuscular Dysplasia; Spontaneous Coronary Artery Dissection; Cervical Artery Dissection

 

Last Updated: 6 Jun 2017

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The Study of the Prevalence Fibromuscular Dysplasia in Patient With Haematoma or Spontaneous Coronary Artery Dissection.
 

Status: Recruiting

Condition Summary: Spontaneous Coronary Artery Dissection; Spontaneous Coronary Artery Haematoma

 

Last Updated: 9 Jun 2016

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