Fibrosing Mediastinitis

Common Name(s)

Fibrosing Mediastinitis

Fibrosing mediastinitis is a condition that affects the area between the lungs (mediastinum) which contains the heart, large blood vessels, windpipe (trachea), esophagus, and lymph nodes. People with fibrosing mediastinitis have varying amounts of scar tissue in the mediastinum which may cause problems for the organs located there. For example, some affected people may develop blocked airways that can interfere with lung function. Others may have compressed blood vessels which can slow or prevent blood flow to and from the heart. The exact cause of fibrosing mediastinitis is not fully understood, but it is not inherited. Many cases are linked to a specific type of fungal infection called histoplasmosis. Treatment depends on which structures of the mediastinum are affected, the severity of the scarring and, in some cases, the cause of the condition.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fibrosing Mediastinitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fibrosing Mediastinitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Fibrosing Mediastinitis" returned 29 free, full-text research articles on human participants. First 3 results:

Clinical Manifestations of Fibrosing Mediastinitis in Chinese Patients.
 

Author(s): Yan Hu, Jian-Xing Qiu, Ji-Ping Liao, Hong Zhang, Zhe Jin, Guang-Fa Wang

Journal: Chin. Med. J.. 2016 11;129(22):2697-2702.

 

Fibrosing mediastinitis (FM) is a rare disease. FM is thought to be related to prior granulomatous mediastinal infection, such as histoplasmosis or tuberculosis. The majority of cases have been reported in endemic regions for histoplasmosis. The characteristics of cases of FM in China, ...

Last Updated: 31 Dec 1969

Go To URL
Pulmonary Hypertension Complicating Fibrosing Mediastinitis.
 

Author(s): Andrei Seferian, Alexandru Steriade, Xavier Jaïs, Olivier Planché, Laurent Savale, Florence Parent, David Amar, Roland Jovan, Elie Fadel, Olivier Sitbon, Gérald Simonneau, Marc Humbert, David Montani

Journal: Medicine (Baltimore). 2015 Nov;94(44):e1800.

 

Fibrosing mediastinitis is caused by a proliferation of fibrous tissue in the mediastinum with encasement of mediastinal viscera and compression of mediastinal bronchovascular structures. Pulmonary hypertension (PH) is a severe complication of fibrosing mediastinitis caused by extrinsic ...

Last Updated: 31 Dec 1969

Go To URL
Fibrosing mediastinitis: a rare complication of histoplasmosis.
 

Author(s): Milesh Patel, Frederic Lu, Maria Hannaway, Katherine Hochman

Journal:

 

We report a case of a 29-year-old man who presented with intermittent haemoptysis for about 18 months. Previously, his symptoms had been diagnosed as musculoskeletal pain and later as pneumonia. CT found a venous infarct in the right lung in addition to extensive lymphadenopathy ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Fibrosing Mediastinitis" returned 3 free, full-text review articles on human participants. First 3 results:

IgG4-related fibrosing mediastinitis diagnosed with computed tomography-guided percutaneous needle biopsy: Two case reports and a review of the literature.
 

Author(s): Satoshi Takanashi, Mitsuhiro Akiyama, Katsuya Suzuki, Kotaro Otomo, Tsutomu Takeuchi

Journal: Medicine (Baltimore). 2018 Jun;97(22):e10935.

 

Immunoglobulin G4-related disease (IgG4-RD) is a fibroinflammatory disease characterized by elevated serum IgG4 levels with infiltration of IgG4+ plasma cells and severe fibrosis in affected tissues. Recently, idiopathic fibrosing mediastinitis (FM), an extremely rare fibroinflammatory ...

Last Updated: 31 Dec 1969

Go To URL
Fibrosing mediastinitis with pulmonary hypertension as a complication of pulmonary vein stenosis: A case report and review of the literature.
 

Author(s): Yidan Li, Xiangli Meng, Yidan Wang, Yuanhua Yang, Xiuzhang Lu

Journal: Medicine (Baltimore). 2018 Jan;97(4):e9694.

 

Fibrosingmediastinitis (FM) is caused by a proliferation of fibrous tissue in the mediastinum encasing the mediastinal viscera that results in compression of mediastinal bronchovascular structures. Pulmonary hypertension (PH) is a severe complication of FM caused by extrinsic compression ...

Last Updated: 31 Dec 1969

Go To URL
Sarcoidosis-associated fibrosing mediastinitis with resultant pulmonary hypertension: a case report and review of the literature.
 

Author(s): Rebecca L Toonkel, Alain C Borczuk, Gregory D Pearson, Evelyn M Horn, Byron M Thomashow

Journal: Respiration. 2010 ;79(4):341-5.

 

Pulmonary hypertension, a common manifestation of advanced sarcoidosis, is thought to result from fibrosis with chronic hypoxia and destruction of small vessels, extrinsic compression of pulmonary arteries, or granulomatous vasculitis. We report a case of sarcoidosis-associated pulmonary ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.