Ganglioglioma

Common Name(s)

Ganglioglioma

A ganglioglioma is a rare type of brain tumor, accounting for approximately 1% of all brain tumors.   Gangliogliomas occur when a single cell in the brain starts to divide into more cells, forming a tumor.   This can occur when the cell randomly acquires changes (mutations) in genes that regulate how a cell divides.  Most gangliogliomas grow slowly and are considered benign.  However, up to 10% of gangliogliomas may grow more rapidly and become malignant, meaning the tumor affects the surrounding brain tissue.     The main treatment for ganglioglioma is removal of the entire tumor during surgery.  If the entire tumor is not removed, it has the potential to recur and may require additional surgery or treatments, such as radiation therapy or chemotherapy.  Unfortunately, because gangliogliomas are quite rare, there is limited information to show that radiation therapy or chemotherapy are effective treatments for this condition.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ganglioglioma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ganglioglioma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ganglioglioma" returned 50 free, full-text research articles on human participants. First 3 results:

Clinical Neuropathology image 5-2016: nNeurofibrillary tangle-rich ganglioglioma.
 

Author(s): Ellen Gelpi, Romana Höftberger, Tanja Würger, Johannes Kerschbaumer, Christian F Freyschlag, Tanja Djurdjevic, Johannes A Hainfellner

Journal: Clin. Neuropathol.. ;35(5):278-9.

 

*Both authors contributed equally.

Last Updated: 14 Sep 2016

Go To URL
Unusual ganglioglioma with extensive calcification and ossification.
 

Author(s): Vikas Shashikant Kavishwar, Kirti G Chadha, Shaikhali Moiz Barodawala, Anuradha Krishna Murthy

Journal: Indian J Pathol Microbiol. ;59(3):395-7.

 

Ganglioglioma is a slow-growing relatively low-grade mixed glioneuronal tumor with most cases corresponding to the WHO Grade I category. It frequently presents with seizures. The temporal lobe is the most common location followed by frontal, parietal, and occipital lobes. These generally ...

Last Updated: 11 Aug 2016

Go To URL
Non-infantile variant of desmoplastic ganglioglioma: Conventional and advanced MR imaging characteristics.
 

Author(s): Betul E Derinkuyu, Murat Ucar, Alp O Borcek, Cagri Damar, Cigdem Oztunali, Ayse Gul Alimli, Oznur Boyunaga

Journal: Neuroradiol J. 2015 Jun;28(3):259-63.

 

Desmoplastic infantile ganglioglioma is a paediatric brain tumor that is commonly seen in the infantile age group. Literature on the non-infantile variant of this low-grade supratentorial neoplasm is very scarce, except for a few case reports. Herein, we report a case of desmoplastic ...

Last Updated: 6 Aug 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ganglioglioma" returned 9 free, full-text review articles on human participants. First 3 results:

Diffusion, Perfusion, and Histopathologic Characteristics of Desmoplastic Infantile Ganglioglioma.
 

Author(s): Chang Y Ho, Melissa Gener, Jose Bonnin, Stephen F Kralik

Journal:

 

We present a case series of a rare tumor, the desmoplastic infantile ganglioglioma (DIG) with MRI diffusion and perfusion imaging quantification as well as histopathologic characterization. Four cases with pathologically-proven DIG had diffusion weighted imaging (DWI) and two of the ...

Last Updated: 20 Oct 2016

Go To URL
Anaplastic ganglioglioma: a report of three cases and review of the literature.
 

Author(s): John Thomas Lucas, Andrew Jonathan Huang, Ryan T Mott, Glenn J Lesser, Stephen Bradley Tatter, Michael David Chan

Journal: J. Neurooncol.. 2015 May;123(1):171-7.

 

Gangliogliomas are rare tumors of the central nervous system that are thought to arise from a glioneuronal precursor and consist of both neuronal and glial elements. Grade III, or anaplastic ganglioglioma (AGG), most commonly affects children and young adults, generally arises in ...

Last Updated: 21 May 2015

Go To URL
Cerebellar ganglioglioma.
 

Author(s): Badr Fedoul, Zouhayr Souirti

Journal: Pan Afr Med J. 2012 ;12():12.

 

The cerebellar location of ganglioglioma (GG) is exceptional. We report one case of a 27-year-old man who underwent an intracranial hypertension syndrome and a static cerebellar syndrome. Brain magnetic resonance images revealed a cyst image in the vermis. Histological study after ...

Last Updated: 24 Jul 2012

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 10 Apr 2017

Go to URL
Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation
 

Status: Recruiting

Condition Summary: Brain Tumor; Low Grade Glioma; Astrocytoma; Ependymoma; Ganglioglioma

 

Last Updated: 2 Mar 2017

Go to URL
A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2
 

Status: Recruiting

Condition Summary: Malignant Glioma of Brain; Astrocytoma; Malignant Astrocytoma; Oligodendroglioma; Anaplastic Oligodendroglioma of Brain (Diagnosis); Mixed Oligo-Astrocytoma; Ependymoma; Ganglioglioma; Pylocytic/Pylomyxoid Astrocytoma

 

Last Updated: 18 Jul 2017

Go to URL