Pseudomyxoma peritonei

Common Name(s)

Pseudomyxoma peritonei, Gelatinous ascites

Pseudomyxoma peritonei is a tumor that most often begins in the appendix.  As the tumor grows, tumor cells may spread into the peritoneal cavity and land on other nearby organs (such as the ovaries or intestines), sometimes forming additional tumors on the surface of these organs.   Pseudomyxoma peritonei is extremely unlikely to grow into these organs (to become invasive) or spread to more distant parts of the body (metastasize); therefore, it is not usually thought of as a malignant tumor.   It is rare, occurring in approximately two out of a million people, and women are affected two to three times more frequently than men.   The first symptoms of pseudomyxoma peritonei are an increase in the size of the belly, appendicitis, or the finding of a mass on the ovary during medical imaging tests.   
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pseudomyxoma peritonei" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pseudomyxoma peritonei" returned 100 free, full-text research articles on human participants. First 3 results:

Urachal mucinous adenocarcinoma with pseudomyxoma peritonei: A case report.
 

Author(s): Lei Liang, Nan Zhou, Hongbin Xu, Damiao Liu, Yiyan Lu, Fang Li, Jun Guo

Journal: Medicine (Baltimore). 2017 Sep;96(35):e7548.

 

Pseudomyxoma peritonei is an unusual clinical condition, and the appendix and ovaries are reported as the primary sites.

Last Updated: 31 Dec 1969

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Multiple components of PKA and TGF-β pathways are mutated in pseudomyxoma peritonei.
 

Author(s): Lilli Saarinen, Pirjo Nummela, Alexandra Thiel, Rainer Lehtonen, Petrus Järvinen, Heikki Järvinen, Lauri A Aaltonen, Anna Lepistö, Sampsa Hautaniemi, Ari Ristimäki

Journal:

 

Pseudomyxoma peritonei (PMP) is a subtype of mucinous adenocarcinoma mainly restricted to the peritoneal cavity and most commonly originating from the appendix. The genetic background of PMP is poorly understood and no targeted treatments are currently available for this fatal disease. ...

Last Updated: 31 Dec 1969

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Physical and chemical characteristics of mucin secreted by pseudomyxoma peritonei (PMP).
 

Author(s): Krishna Pillai, Javed Akhter, Ahmed Mekkawy, Terence C Chua, David L Morris

Journal:

 

Background: Pseudomyxoma peritonei (PMP) is a rare disease with excess intraperitoneal mucin secretion. Treatment involves laparotomy, cytoreduction and chemotherapy that is very invasive with patients often acquiring numerous compromises. Hence a mucolytic comprising of bromelain ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pseudomyxoma peritonei" returned 10 free, full-text review articles on human participants. First 3 results:

Mucinous epithelial neoplasms of the appendix and pseudomyxoma peritonei.
 

Author(s): Joseph Misdraji

Journal: Mod. Pathol.. 2015 Jan;28 Suppl 1():S67-79.

 

The classification of appendiceal mucinous neoplasms has been controversial, largely focused on a particular subset of low-grade mucinous tumors that, despite their innocuous appearance, can disseminate to the peritoneal cavity as pseudomyxoma peritonei (PMP). Recent WHO classification ...

Last Updated: 31 Dec 1969

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Secreted mucins in pseudomyxoma peritonei: pathophysiological significance and potential therapeutic prospects.
 

Author(s): Afshin Amini, Samar Masoumi-Moghaddam, Anahid Ehteda, David Lawson Morris

Journal:

 

Pseudomyxoma peritonei (PMP, ORPHA26790) is a clinical syndrome characterized by progressive dissemination of mucinous tumors and mucinous ascites in the abdomen and pelvis. PMP is a rare disease with an estimated incidence of 1-2 out of a million. Clinically, PMP usually presents ...

Last Updated: 31 Dec 1969

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Pathologic diagnosis, origin, and natural history of pseudomyxoma peritonei.
 

Author(s): Rebecca Buell-Gutbrod, Katja Gwin

Journal: Am Soc Clin Oncol Educ Book. 2013 ;():221-5.

 

Mucinous ascites and pools of mucin within the peritoneal cavity associated with neoplastic, mucinous epithelium are the characteristic features of pseudomyxoma peritonei (PMP). Clinically, PMP presents with abdominal distension and gelatinous ascites. In female patients, pelvic masses ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Antibiotic Treatment and Long-term Outcomes of Patients With Pseudomyxoma Peritonei of Appendiceal Origin
 

Status: Recruiting

Condition Summary: Pseudomyxoma Peritonei; Appendiceal Neoplasms

 

Last Updated: 16 Feb 2017

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HIPEC Using High Intra-abdominal Pressure
 

Status: Recruiting

Condition Summary: Pseudomyxoma Peritonei; Colorectal Cancer

 

Last Updated: 27 Oct 2016

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