Genital herpes

Common Name(s)

Genital herpes

Genital herpes is a common sexually transmitted disease that affects roughly half a billion people worldwide. Most individuals with genital herpes don’t realize they are carrying the virus. It is caused by the herpes simplex virus Type 1 or Type 2 (HSV-1, HSV-2). HSV resides in nerve cells until it moves to the surface of the skin. During the beginning of HSV infection, symptoms may include fever, aches, swollen lymph nodes and blisters that break and form sores. Later outbreaks will produce blisters that become sores in the area of infection, and may not be limited to the genitals. Signs of an outbreak may include pain or tingling in the infected area or pain in the lower back, but are not always present. An individual infected by genital herpes can be at a greater risk of HIV infection. Herpes can sometimes cause miscarriage and early delivery and can be passed to an infant during delivery.

HSV viruses are spread through contact. HSV-1 can be spread from the mouth to the genitals during oral sex. HSV-2 can be transmitted through sexual contact or skin contact in the genital area. HSV-1 and HSV-2 will both result in genital herpes if the virus has a chance to infect the genital area. While the virus is active and travels to the skin’s surface, it makes more copies of the viral cells and sheds. Contact with the shedding virus will result in transmission of the disease as will contact with the fluid from a blister in an outbreak. However, HSV cannot survive outside of the human body. Human to human contact is how the virus spreads, not touching an infected surface.

Herpes can be diagnosed through blood tests and cell culture. Antiviral medications can reduce outbreaks and the risk of spreading genital herpes. If you have been diagnosed with genital herpes, talk to your doctor about the most current treatment options. Support groups are available for more resources and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Genital herpes" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Genital herpes" returned 295 free, full-text research articles on human participants. First 3 results:

Dorsal longitudinal foreskin cut is associated with reduced risk of HIV, syphilis and genital herpes in men: a cross-sectional study in Papua New Guinea.
 

Author(s): Andrew J Vallely, David MacLaren, Matthew David, Pamela Toliman, Angela Kelly-Hanku, Ben Toto, Rachael Tommbe, Zure Kombati, Petronia Kaima, Kelwyn Browne, Clement Manineng, Lalen Simeon, Claire Ryan, Handan Wand, Peter Hill, Greg Law, Peter M Siba, W John H McBride, John M Kaldor

Journal: J Int AIDS Soc. 2017 Apr;20(1):1-11.

 

Various forms of penile foreskin cutting are practised in Papua New Guinea. In the context of an ecological association observed between HIV infection and the dorsal longitudinal foreskin cut, we undertook an investigation of this relationship at the individual level.

Last Updated: 13 Apr 2017

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Clinical study in genital herpes: natural Gene-Eden-VIR/Novirin versus acyclovir, valacyclovir, and famciclovir.
 

Author(s): Hanan Polansky, Adrian Javaherian, Edan Itzkovitz

Journal:

 

This paper reports the results of a clinical study that tested the effect of suppressive treatment with the botanical product Gene-Eden-VIR/Novirin on the number of genital herpes outbreaks. The results in this study were compared to those published in clinical studies of acyclovir, ...

Last Updated: 13 Sep 2016

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Role of type-specific herpes simplex virus-1 and 2 serology as a diagnostic modality in patients with clinically suspected genital herpes: A comparative study in Indian population from a tertiary care hospital.
 

Author(s): Vrushali Patwardhan, Preena Bhalla

Journal: Indian J Pathol Microbiol. ;59(3):318-21.

 

Type-specific serology (TSS) test for herpes simplex virus (HSV) have been used as a research tool in seroepidemiological studies for some years. However, TSS as a diagnostic modality for diagnosis of current episode of genital herpes is not well documented.

Last Updated: 11 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Genital herpes" returned 31 free, full-text review articles on human participants. First 3 results:

Extensive and refractory genital herpes in human immunodeficiency virus-infected patient successfully treated with imiquimod: Case report and literature review.
 

Author(s): Helena Reich Camasmie, Caroline Barbosa, Omar Lupi, Ricardo Barbosa Lima, Marcio Serra, Antonio Macedo D'Acri, Carlos José Martins

Journal: Indian J Dermatol Venereol Leprol. ;83(2):256-259.

 

Last Updated: 6 Feb 2017

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Collaboration with a midwife in the care of a pregnant patient with recurrent genital herpes simplex virus.
 

Author(s): Michael Mohan, John Jordan, Michelle Levy

Journal: Can Fam Physician. 2016 Jul;62(7):562-4.

 

Last Updated: 14 Jul 2016

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Genital Herpes: A Review.
 

Author(s): Mary Jo Groves

Journal: Am Fam Physician. 2016 Jun;93(11):928-34.

 

Genital herpes is a common sexually transmitted disease, affecting more than 400 million persons worldwide. It is caused by herpes simplex virus (HSV) and characterized by lifelong infection and periodic reactivation. A visible outbreak consists of single or clustered vesicles on ...

Last Updated: 10 Jun 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The VIBLOK SAfety and perFormancE Trial
 

Status: Recruiting

Condition Summary: HSV-2 Infection; Genital Herpes

 

Last Updated: 30 Mar 2017

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Comparative Effectiveness of Treatment Options for Genital Herpes Infection to Reduce Adverse Pregnancy Outcomes
 

Status: Recruiting

Condition Summary: HSV-2 Infection; PreTerm Birth; Pregnancy Complications

 

Last Updated: 15 Mar 2017

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