Glomerulonephritis

Common Name(s)

Glomerulonephritis

Glomerulonephritis is a type of kidney disease in which there is inflammation of the glomeruli, the tiny filters that remove excess waste and fluids from the blood.  It may be acute or chronic (coming on gradually), and may occur on its own (primary) or be caused by another condition (secondary). Signs and symptoms may depend on the type and cause of the condition and may include blood in the urine; foamy urine; swelling of the face, eyes, or other body parts; abdominal pain; high blood pressure; fatigue; and/or other symptoms. If the condition is severe or prolonged, the kidneys can become damaged.  It may be caused by a variety of infections and diseases, and sometimes the cause is unknown. Treatment depends on the cause, type and severity of the condition.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Glomerulonephritis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Glomerulonephritis" returned 1227 free, full-text research articles on human participants. First 3 results:

Extranodal NK/T-cell Lymphoma, Nasal Type Accompanied by PR3-ANCA-associated Glomerulonephritis.
 

Author(s): Yuta Tamoto, Ryo Ishida, Kazuya Shiogama, Hiroshi Kado, Michitsugu Kamezaki, Yoshiaki Chinen, Yosuke Matsumoto, Tetsuro Kusaba, Eiichi Konishi, Yutaka Tsutsumi, Keiichi Tamagaki

Journal: Intern. Med.. 2017 ;56(15):2007-2012.

 

A 62-year-old man exhibiting nasal obstruction and glomerulonephritis with proteinase 3-antineutrophil cytoplasmic antibodies (PR3-ANCAs) was diagnosed with extranodal NK/T-cell lymphoma, nasal type (ENKL) with infiltration of neutrophils with apoptosis. Chemoradiotherapy reduced ...

Last Updated: 31 Dec 1969

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A Rare Adult Case with Diffuse Segmental Membranous Glomerulonephritis.
 

Author(s): Yoshihide Fujigaki, Yoshifuru Tamura, Shigeru Shibata, Fukuo Kondo, Takamasa Iwakura, Kenichiro Kojima, Yutaka Yamaguchi, Shunya Uchida

Journal: Intern. Med.. 2017 ;56(13):1691-1695.

 

A 71-year-old man with hypertension and diabetes mellitus presented with proteinuria. Laboratory data showed proteinuria of 3.1 g/g creatinine, serum albumin of 3.5 g/dL and serum creatinine of 1.03 mg/dL without autoantibodies. A renal biopsy revealed segmental granular IgG depositions ...

Last Updated: 31 Dec 1969

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Glomerulonephritis and granulomatous vasculitis in kidney as a complication of the use of BRAF and MEK inhibitors in the treatment of metastatic melanoma: A case report.
 

Author(s): Mehdi Maanaoui, Camille Saint-Jacques, Viviane Gnemmi, Marie Frimat, Arnaud Lionet, Marc Hazzan, Christian Noël, François Provot

Journal: Medicine (Baltimore). 2017 Jun;96(25):e7196.

 

BRAF and MEK inhibitors have significantly improved the prognosis of metastatic melanoma, by inhibiting both the mitogen-activated protein kinase (MAP-kinase) pathway. They are associated with infrequent adverse kidney events. Most of these are related to the use of BRAF inhibitors ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Glomerulonephritis" returned 140 free, full-text review articles on human participants. First 3 results:

Targeting the tyrosine kinase signalling pathways for treatment of immune-mediated glomerulonephritis: from bench to bedside and beyond.
 

Author(s): Terry King-Wing Ma, Stephen P McAdoo, Frederick Wai Keung Tam

Journal: Nephrol. Dial. Transplant.. 2017 01;32(suppl_1):i129-i138.

 

Glomerulonephritis (GN) affects patients of all ages and is an important cause of morbidity and mortality. Non-selective immunosuppressive drugs have been used in immune-mediated GN but often result in systemic side effects and occasionally fatal infective complications. There is ...

Last Updated: 31 Dec 1969

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CD4T Cell Fate in Glomerulonephritis: A Tale of Th1, Th17, and Novel Treg Subtypes.
 

Author(s): Christan F Krebs, Oliver M Steinmetz

Journal: Mediators Inflamm.. 2016 ;2016():5393894.

 

Multiple studies have identified CD4T cells as central players of glomerulonephritis (GN). Cells of the Th1 and Th17 responses cause renal tissue damage, while Tregs mediate protection. Recently, a high degree of plasticity among these T cell lineages was proposed. During inflammation, ...

Last Updated: 31 Dec 1969

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Nivolumab-associated acute glomerulonephritis: a case report and literature review.
 

Author(s): Kyungsuk Jung, Xu Zeng, Marijo Bilusic

Journal:

 

Immune checkpoint inhibitors are changing the landscape of oncology treatment as they are significantly improving treatment for multiple malignancies. Nivolumab, an anti-programmed death 1 antibody, is a US Food and Drug Administration-approved treatment for melanoma, non-small cell ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

ACE-inhibitors in Extracapillary Glomerulonephritis
 

Status: Recruiting

Condition Summary: Extracapillary Glomerulonephritis

 

Last Updated: 19 Jul 2017

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Effect of Rituximab in Treatment of Membranoproliferative Glomerulonephritis
 

Status: Not yet recruiting

Condition Summary: Membranoproliferative Glomerulonephritis

 

Last Updated: 15 Jun 2017

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Acute Post Streptococcal Glomerulonephritis
 

Status: Not yet recruiting

Condition Summary: PSGN - Post-Streptococcal Glomerulonephritis

 

Last Updated: 13 Jun 2017

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