Good Syndrome

Common Name(s)

Good Syndrome

Good syndrome is a rare, adult-onset primary immunodeficiency suspected in patients who exhibit hypogammaglobulinemia and low levels of B cells along with a benign thymic tumor (thymoma) on chest X-ray. Symptoms include frequent opportunistic infections involving the sinuses and lungs, including severe CMV disease, P. carinii pneumonia, and mucocutaneous candidiasis. While the cause of Good syndrome remains unknown, there is some evidence that a defect of the bone marrow is involved. Treatment includes removal of the thymic tumor and immunoglobulin replacement.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Good Syndrome" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Good Syndrome" returned 58 free, full-text research articles on human participants. First 3 results:

[Acquired hypogammaglobulinemia associated with thymoma: Good syndrome].
 

Author(s): Samira Aouadi, Najla Ghrairi, Emna Braham, Manel Kaabi, Sonia Maâlej, Leila Douik Elgharbi

Journal:

 

Good syndrome (GS) is defined as the association between thymoma and immune deficiency. It is often complicated by broncho-pulmonary bacterial infections and rhinosinusitis. This disease accounts for only 5% of all parathymic syndromes. These recurrent respiratory infections can cause ...

Last Updated: 31 Dec 1969

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Good health indicators in children with Down syndrome: High frequency of exclusive breastfeeding at 6 months.
 

Author(s): Lorena Génova, Jaime Cerda, Catalina Correa, Natalia Vergara, Macarena Lizama

Journal: Rev Chil Pediatr. 2018 Feb;89(1):32-41.

 

To describe the frequency of exclusive breastfeeding at 6 months in binomial of mother and in fants with Down Syndrome (DS) attending at the Health net UC CHRISTUS (PSSPSD-UC), and iden tify the main factors associated with exclusive breastfeeding cessation.

Last Updated: 31 Dec 1969

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Hand-Foot Syndrome and Post-Progression Treatment Are the Good Predictors of Better Survival in Advanced Hepatocellular Carcinoma Treated with Sorafenib: A Multicenter Study.
 

Author(s): Chikara Ogawa, Masahiro Morita, Akina Omura, Teruyo Noda, Atsushi Kubo, Toshihiro Matsunaka, Hiroyuki Tamaki, Mitsushige Shibatoge, Akemi Tsutsui, Tomonori Senoh, Takuya Nagano, Kouichi Takaguchi, Joji Tani, Asahiro Morishita, Hirohito Yoneyama, Tsutomu Masaki, Akio Moriya, Masaharu Ando, Akihiro Deguchi, Yasutaka Kokudo, Yasunori Minami, Kazuomi Ueshima, Toshiharu Sakurai, Naoshi Nishida, Masatoshi Kudo

Journal: Oncology. 2017 ;93 Suppl 1():113-119.

 

To determine the relationship between treatment outcomes and hand-foot syndrome (HFS), and the relationship between survival rate and post-progression treatment after sorafenib therapy.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Good Syndrome" returned 6 free, full-text review articles on human participants. First 3 results:

Cytokine profiles contribute to understanding the pathogenic difference between Good syndrome and oral lichen planus: two case reports and literature review.
 

Author(s): Takashi Maehara, Masafumi Moriyama, Shintaro Kawano, Jun-Nosuke Hayashida, Sachiko Furukawa, Miho Ohta, Akihiko Tanaka, Masaki Yamauchi, Yukiko Ohyama, Tamotsu Kiyoshima, Seiji Nakamura

Journal: Medicine (Baltimore). 2015 Apr;94(14):e704.

 

We described and analyzed the pathogenic difference between Good syndrome (GS) and oral lichen planus (OLP) in oral mucosa. Good syndrome (GS) is a rare disease characterized by B and T cell immunodeficiency associated with hypogammaglobulinemia and thymoma. GS patients frequently ...

Last Updated: 31 Dec 1969

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Good syndrome, a rare disease that physicians cannot afford to overlook; case report and review of literature.
 

Author(s): Asim Idress, Ali Saeed Wahla

Journal: J Pak Med Assoc. 2013 Dec;63(12):1541-3.

 

Last Updated: 31 Dec 1969

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Abdominal cocoon syndrome: preoperative diagnostic criteria, good clinical outcome with medical treatment and review of the literature.
 

Author(s): Aynur Solak, İlhami Solak

Journal: Turk J Gastroenterol. 2012 ;23(6):776-9.

 

Sclerosing encapsulating peritonitis, or abdominal cocoon syndrome, was described firstly in young adolescent girls. It is characterized by a thick fibrotic peritoneum that wraps the bowel in a concertina-like fashion with some adhesions. We report a man with intermittent intestinal ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Serum Concentrations, Physical and Psychological Well-being in Metabolic Syndrome
 

Status: Recruiting

Condition Summary: Metabolic Syndrome

 

Last Updated: 10 Nov 2017

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AMT-PET in Monitoring Telotristat Etiprate Treatment in Participants With Metastatic Well Differentiated Neuroendocrine Neoplasm
 

Status: Not yet recruiting

Condition Summary: Carcinoid Syndrome; Metastatic Nonfunctional Well Differentiated Neuroendocrine Neoplasm

 

Last Updated: 10 Apr 2018

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A Study to Test if TEV-50717 is Effective in Relieving Tics Associated With Tourette Syndrome
 

Status: Recruiting

Condition Summary: Tourette Syndrome

 

Last Updated: 1 Aug 2018

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