HAIR-AN Syndrome

Common Name(s)

HAIR-AN Syndrome

HAIR-AN syndrome is a condition that affects women. It is characterized by hyperandrogenism, insulin resistance, and acanthosis nigricans. Insulin resistance is a condition in which the body produces insulin but does not use it properly. This causes the pancreas to produce more insulin. High levels of insulin stimulate the ovaries to make too much androgen, leading too excessive  hair growth, acne, and irregular periods. Insulin resistance can also lead to diabetes, high blood pressure, heart disease, and excessive growth and darkening of the skin (aconthosis nigricans). Women with HAIR-AN may be born with insulin resistance or acquire it over time.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "HAIR-AN Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "HAIR-AN Syndrome" returned 4 free, full-text research articles on human participants. First 3 results:

Crooked fingers and sparse hair: an interesting case of trichorhinophalangeal syndrome type 1.
 

Author(s): Ramakrishna Narayanan, Srinivasa Chennareddy

Journal:

 

Trichorhinophalangeal syndrome type 1 is a rare skeletal dysplasia of autosomal-dominant inheritance due to defects in the TRPS-1 gene. The syndrome is characterised by sparse slow-growing hair, a bulbous pear-shaped nose, cone-shaped epiphyses and deformities of the interphalangeal ...

Last Updated: 28 Jan 2015

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Clinical profiles, occurrence, and management of adolescent patients with HAIR-AN syndrome.
 

Author(s): Hatim A Omar, Stephanie Logsdon, Jessica Richards

Journal:

 

The syndrome of hyperandrogenism, insulin resistance, and acanthosis nigricans (HAIR-AN) is a subphenotype of the polycystic ovary syndrome. It is one of the most common causes of menstrual problems, hyperandrogenic symptoms, and insulin resistance among young women. Review of clinical ...

Last Updated: 19 Jul 2004

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HAIR-AN syndrome: a multisystem challenge.
 

Author(s): K B Elmer, R M George

Journal: Am Fam Physician. 2001 Jun;63(12):2385-90.

 

HAIR-AN syndrome is an acronym for an unusual multisystem disorder in women that consists of hyperandrogenism (HA), insulin resistance (IR) and acanthosis nigricans (AN). The precipitating abnormality is thought to be insulin resistance, with a secondary increase in insulin levels ...

Last Updated: 29 Jun 2001

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "HAIR-AN Syndrome" returned 2 free, full-text review articles on human participants. First 3 results:

Navigating adolescence with a chronic health condition: a perspective on the psychological effects of HAIR-AN syndrome on adolescent girls.
 

Author(s): Kimberly K McClanahan, Hatim A Omar

Journal:

 

HAIR-AN syndrome is a subphenotype of polycystic ovary syndrome and is characterized by acne, obesity, hirsutism, and acanthosis nigricans. It usually manifests in early adolescence, a time of significant developmental change in females across physical, cognitive, social, and emotional ...

Last Updated: 30 Oct 2006

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Androgen excess disorders in women: the severe insulin-resistant hyperandrogenic syndrome, HAIR-AN.
 

Author(s): Kristin M Rager, Hatim A Omar

Journal:

 

HAIR-AN syndrome (hyperandrogenism, insulin resistance, acanthosis nigricans) is a subset of the polycystic ovary syndrome, where the patients demonstrate severe insulin resistance. It is theorized that both genetic and environmental factors, such as obesity, give rise to the development ...

Last Updated: 25 Jan 2006

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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