HELLP syndrome

Common Name(s)

HELLP syndrome

HELLP syndrome is a rare but serious illness in pregnancy. This condition can start quickly, most often in the last 3 months of pregnancy (the third trimester). It can also start soon after the baby is delivered. HELLP stands for Hemolysis, Elevated Liver enzyme levels and a Low Platelet count. These problems are often found in women with this syndrome. These problems, along with the high blood pressure commonly found in association with HELLP syndrome, can lead to problems for both the mother and the baby.  Many cases of HELLP syndrome are associated with  preeclampsia or eclampsia.  The exact cause of HELLP syndrome remains unknown, making it difficult to determine which women will be affected.  Treatment may involve medication and/or delivery of the baby.    
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "HELLP syndrome" for support, advocacy or research.

APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

Last Updated: 12 Aug 2013

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H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

Last Updated: 23 Oct 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "HELLP syndrome" for support, advocacy or research.

APS Foundation of America, Inc.

The APS Foundation of America, Inc. is dedicated to fostering and facilitating joint efforts in the areas of education, public awareness, research and patient services in an effective and ethical manner.

http://www.apsfa.org

Last Updated: 12 Aug 2013

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H.E.L.L.P. Syndrome International Foundation, S.a, UK, USA

HELLP Syndrome is a life-threatening condition to both mother and unborn baby during gestation. Our goal: To enhance and extend life.

Last Updated: 19 Aug 2013

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Preeclampsia Foundation

The Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices. We envision a world where preeclampsia no longer threatens the lives of mothers and babies.

http://www.preeclampsia.org

Last Updated: 23 Oct 2014

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General Support Organizations

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General Resources

Antiphospholipid Antibody Syndrome (APS) & Pregnancy

Antiphospholipid antibody syndrome (APS) is an illness that involve the immune system, and causes increased clotting of the blood. Normally antibodies, chemicals made by the immune system, are helpful in fighting germs or viral infections from outsid

Updated 13 Nov 2012

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APS Foundation of America, Inc Fan Page

The APS Foundation of America, Inc. is the leading United States nonprofit health agency dedicated to bringing national awareness to Antiphospholipid Antibody Syndrome (APS).

Updated 13 Nov 2012

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The Preeclampsia Registry

The Preeclampsia Registry is a "Living Database" bringing together those affected, their family members, and researchers to advance knowledge and discover preventions and treatments for preeclampsia, HELLP syndrome, and related hypertensive disorders

Updated 23 Oct 2014

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Blogs

APS Friends & Support Forum

Are you looking for Support for Antiphospholipid Antibody Syndrome, APS, APLS, APLA, Hughes Syndrome, or Sticky Blood? Well you've come to the right place! This is an private forum for people who have Antiphospholipid Antibody Syndrome, friends, fam

Updated 13 Nov 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "HELLP syndrome" returned 112 free, full-text research articles on human participants. First 3 results:

[Ruptured subscapular liver hematoma in context of HELLP syndrome.]
 

Author(s): María Paz Henríquez-Villaseca, Alejandra Catalán-Barahona, José Lattus-Olmos, Karina Vargas-Valdebenito, Solange Silva-Ruz

Journal: Rev Med Chil. 2018 Jun;146(6):753-761.

 

Ruptured subscapular liver hematoma in context of HELLP syndrome is a rare complication with high mortality. Clinical presentation is nonspecific: epigastric pain, right upper quadrant pain and shoulder pain, should however provide high index of suspicion. Termination of pregnancy ...

Last Updated: 31 Dec 1969

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Pravastatin for prevention of HELLP syndrome: A case report.
 

Author(s): Lucia Anna Otten, Katrin van der Ven, Marietta Kühr, Ulrich Gembruch, Waltraut Maria Merz

Journal: Medicine (Baltimore). 2017 Oct;96(42):e8229.

 

Pravastatin has emerged for prevention and treatment of preeclampsia; no reports are available on pravastatin and HELLP (hemolysis, elevated liver enzymes and low platelets) syndrome.

Last Updated: 31 Dec 1969

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Importance of correctly interpreting magnetic resonance imaging to diagnose posterior reversible encephalopathy syndrome associated with HELLP syndrome: a case report.
 

Author(s): Syuichi Tetsuka, Hiroaki Nonaka

Journal:

 

Severe haemolysis, elevated liver enzyme levels, and low platelet count (HELLP) syndrome in pregnancy are possible underlying trigger factors for posterior reversible encephalopathy syndrome (PRES). Magnetic resonance imaging (MRI) shows diffuse signal abnormalities involving the ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "HELLP syndrome" returned 18 free, full-text review articles on human participants. First 3 results:

Life-threatening bleeding from gastric dieulafoy's lesion in a pregnant woman with hellp syndrome: a case report and literature review.
 

Author(s): Chen Si, Zhu Xiuli, Xie Li, Jia Yong, Zhou Ying, Zhang Kaiguang

Journal:

 

Dieulafoy's lesion (DL) is one of the rare causes of upper gastrointestional bleeding. This disease is characterized by small sub-mucosal arteriole that eroded the stomach mucosa and cause severe upper GI bleeding without obvious ulceration. The most common location is fundus area ...

Last Updated: 31 Dec 1969

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No Hypertensive Disorder of Pregnancy; No Preeclampsia-eclampsia; No Gestational Hypertension; No Hellp Syndrome. Vascular Disorder of Pregnancy Speaks for All.
 

Author(s): Yifru Berhan

Journal: Ethiop J Health Sci. 2016 Mar;26(2):177-86.

 

Hypertensive disorders complicate 5%-10% of pregnancies with increasing incidence mainly due to upward trends in obesity globally. In the last century, several terminologies have been introduced to describe the spectrum of this disease. The current and widely used classification of ...

Last Updated: 31 Dec 1969

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Corticosteroid Therapy for Management of Hemolysis, Elevated Liver Enzymes, and Low Platelet Count (HELLP) Syndrome: A Meta-Analysis.
 

Author(s): Minhong Mao, Chen Chen

Journal:

 

BACKGROUND Hemolysis, elevated liver enzymes, and low platelet count (HELLP) syndrome is a severe condition of pregnancy that is associated with significant morbidity and mortality. Corticoteroid (CORT) therapy is common in the management of HELLP syndrome. This study evaluates the ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Influence of Conditional Workout Postpartum on Arterial Stiffness Among Women With Status After Preeclampsia, Superimposed Preeclampsia or HELLP-syndrome
 

Status: Recruiting

Condition Summary: Preeclampsia; Superimposed Preeclampsia; HELLP Syndrome

 

Last Updated: 10 Mar 2018

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Pancreatic Stone Protein (PSP) in Pregnant Women
 

Status: Recruiting

Condition Summary: Pregnancy; HELLP Syndrome; Preterm Premature Rupture of Fetal Membranes; Preeclampsia

 

Last Updated: 6 Nov 2017

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Women Specific Cardiac Recovery After Preeclampsia
 

Status: Recruiting

Condition Summary: Pre-Eclampsia; Pregnancy; HELLP Syndrome; Intrauterine Growth Restriction

 

Last Updated: 24 Aug 2018

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