HHV-6 encephalitis

Common Name(s)

HHV-6 encephalitis

HHV-6 encephalitis refers to inflammation of the brain due to an infection with human herpesvirus 6.  People who have undergone allogeneic hematopoietic cell transplantation are at an increased risk for developing HHV-6 encephalitis, particularly when umbilical cord blood stem cells are used.  People with immune system disorders may also be at an increased risk for developing this infection. Signs and symptoms vary, but often include confusion, anterograde amnesia (difficulty learning new information following the onset of amnesia), short-term memory loss, and seizures. Diagnosis often involves lumbar puncture, virus testing, and MRI. EEG's may also be recommended when seizures are suspected. HHV-6 encephalitis is treated with an antiviral agent with activity against HHV-6. Long term outlook (chance of full recovery) can vary considerably depending individual patient factors.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "HHV-6 encephalitis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "HHV-6 encephalitis" returned 3 free, full-text research articles on human participants. First 3 results:

HHV-6 encephalitis presenting as status epilepticus in an immunocompetent patient.
 

Author(s): Lokesh Shahani

Journal:

 

Human herpes virus 6 (HHV-6) infections are frequently detected in patients with immunosuppressed transplant; however, reactivation in an immunocompetent patient is rarely reported. The author reports the case of a 65-year-old woman presenting with status epilepticus with foci in ...

Last Updated: 20 Sep 2014

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A case of pneumonitis and encephalitis associated with human herpesvirus 6 (HHV-6) infection after bone marrow transplantation.
 

Author(s): T Nakayama, F Okada, Y Ando, K Honda, M Ogata, K Goto, J Kadota, H Mori

Journal: Br J Radiol. 2010 Dec;83(996):e255-8.

 

Human herpesvirus 6 (HHV-6)-associated encephalitis or pneumonitis has been reported in immunocompetent and immunosuppressed individuals. Several MRI studies in patients with HHV-6-associated encephalitis have been presented. However, to the best of our knowledge, no studies describing ...

Last Updated: 22 Nov 2010

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Severe amnesia due to HHV-6 encephalitis after allogenic stem cell transplantation.
 

Author(s): A M Visser, G J J van Doornum, J J Cornelissen, M J van den Bent

Journal: Eur. Neurol.. 2005 ;54(4):233-4.

 

Last Updated: 1 Feb 2006

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Reviews from the PubMed Database

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The terms "HHV-6 encephalitis" returned 0 free, full-text review articles on human participants.

 
 
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