Haemophilus Influenzae

Common Name(s)

Haemophilus Influenzae

Haemophilus Influenzae is an infectious bacterium that can cause problems for many systems of the body. There are six types (a-f) of the bacterium that can cause serious infections in infants and children under the age of five. The bacteria are passed from person to person through direct contact or respiratory droplets from coughing or sneezing. Haemophilus influenzae are most dangerous when they have infected the bloodstream (bacteremia), lungs (pneumonia), or brain (meningitis). Each of these infections correlates to a different set of symptoms. Haemophilus influenzae infections can be treated with antibiotics. In some severe cases, hospitalization may occur as well.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Haemophilus Influenzae" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Haemophilus Influenzae" returned 1409 free, full-text research articles on human participants. First 3 results:

Impact of Haemophilus influenzae type b conjugate vaccination on hospitalization for invasive disease in children fifteen years after its introduction in Italy.
 

Author(s): Domenico Martinelli, Chiara Azzari, Paolo Bonanni, Susanna Esposito, Elisabetta Franco, Giancarlo Icardi, Gianvincenzo Zuccotti, Rosa Prato

Journal: Vaccine. 2017 11;35(46):6297-6301.

 

In Italy, Hib conjugate vaccine was introduced for infants in 1999 and included in the DTaP-HBV-IPV-Hib combination in 2001, with an uptake of 83.4% in 2002, >90% by 2005, and >95% by 2011. We estimated the impact of Hib vaccination on hospitalizations for H. influenzae invasive disease ...

Last Updated: 31 Dec 1969

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Epidemiology of invasive pneumococcal and Haemophilus influenzae diseases in Northwestern Ontario, Canada, 2010-2015.
 

Author(s): Vic Eton, Annette Schroeter, Len Kelly, Michael Kirlew, Raymond S W Tsang, Marina Ulanova

Journal: Int. J. Infect. Dis.. 2017 Dec;65():27-33.

 

North American indigenous populations experience a high burden of invasive bacterial infections. Because Streptococcus pneumoniae and Haemophilus influenzae have multiple antigenic variants, the existing vaccines cannot prevent all cases. This study addresses the current epidemiology ...

Last Updated: 31 Dec 1969

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Modelling the effects of booster dose vaccination schedules and recommendations for public health immunization programs: the case of Haemophilus influenzae serotype b.
 

Author(s): Nadia A Charania, Seyed M Moghadas

Journal:

 

Haemophilus influenzae serotype b (Hib) has yet to be eliminated despite the implementation of routine infant immunization programs. There is no consensus regarding the number of primary vaccine doses and an optimal schedule for the booster dose. We sought to evaluate the effect of ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Haemophilus Influenzae" returned 49 free, full-text review articles on human participants. First 3 results:

Insights on persistent airway infection by non-typeable Haemophilus influenzae in chronic obstructive pulmonary disease.
 

Author(s): Christian P Ahearn, Mary C Gallo, Timothy F Murphy

Journal: Pathog Dis. 2017 Jun;75(4):.

 

Non-typeable Haemophilus influenzae (NTHi) is the most common bacterial cause of infection of the lower airways in adults with chronic obstructive pulmonary disease (COPD). Infection of the COPD airways causes acute exacerbations, resulting in substantial morbidity and mortality. ...

Last Updated: 31 Dec 1969

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Host-pathogen interactions of nontypeable Haemophilus influenzae: from commensal to pathogen.
 

Author(s): Benjamin Luke Duell, Yu-Ching Su, Kristian Riesbeck

Journal: FEBS Lett.. 2016 Nov;590(21):3840-3853.

 

Nontypeable Haemophilus influenzae (NTHi) is a commensal microbe often isolated from the upper and lower respiratory tract. This bacterial species can cause sinusitis, acute otitis media in preschool children, exacerbations in patients suffering from chronic obstructive pulmonary ...

Last Updated: 31 Dec 1969

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The Lung Immune Response to Nontypeable Haemophilus influenzae (Lung Immunity to NTHi).
 

Author(s): Paul T King, Roleen Sharma

Journal: J Immunol Res. 2015 ;2015():706376.

 

Haemophilus influenzae is divided into typeable or nontypeable strains based on the presence or absence of a polysaccharide capsule. The typeable strains (such as type b) are an important cause of systemic infection, whilst the nontypeable strains (designated as NTHi) are predominantly ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 9 Nov 2017

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Evaluation of Immunogenicity and Safety of a Booster Dose of Infanrix Hexa™ in Healthy Infants Born to Mothers Vaccinated With Boostrix™ During Pregnancy or Immediately Post-delivery
 

Status: Recruiting

Condition Summary: Diphtheria; Hepatitis B; Acellular Pertussis; Haemophilus Influenzae Type b; Tetanus; Poliomyelitis

 

Last Updated: 31 May 2018

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Systematic Search for Primary Immunodeficiency in Adults With Infections
 

Status: Recruiting

Condition Summary: Complement Deficiency; Antibody Deficiency; Chronic Sinus Infection; Meningitis, Bacterial; Pneumonia, Bacterial; Otitis Media; Streptococcal Infection; Neisseria Infections; Haemophilus Influenza; Pneumococcal Infections

 

Last Updated: 15 May 2018

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