Hantavirus Pulmonary Syndrome

Common Name(s)

Hantavirus Pulmonary Syndrome

Hantavirus pulmonary syndrome (HPS) is a severe, respiratory disease caused by infection with a hantavirus. People can become infected with a hantavirus through contact with hantavirus-infected rodents or their saliva, urine and/or droppings. Early symptoms universally include fatigue, fever and muscle aches (especially in the thighs, hips, and/or back), and sometimes include headaches, dizziness, chills, and abdominal problems such as nausea, vomiting, diarrhea, and pain. Later symptoms of the syndrome occur 4 to 10 days after initial onset and include coughing and shortness of breath. HPS can be fatal; approximately 38% of individuals with HPS do not survive. There is no cure or specific treatment for HPS, but early diagnosis and treatment in intensive care may increase the chance of recovery.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hantavirus Pulmonary Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hantavirus Pulmonary Syndrome" returned 98 free, full-text research articles on human participants. First 3 results:

Hantavirus Pulmonary Syndrome Caused by Maripa Virus in French Guiana, 2008-2016.
 

Author(s): Séverine Matheus, Hatem Kallel, Claire Mayence, Laetitia Bremand, Stéphanie Houcke, Dominique Rousset, Vincent Lacoste, Benoit de Thoisy, Didier Hommel, Anne Lavergne

Journal: Emerging Infect. Dis.. 2017 10;23(10):1722-1725.

 

We report 5 human cases of hantavirus pulmonary syndrome found during surveillance in French Guiana in 2008-2016; of the 5 patients, 4 died. This pathogen should continue to be monitored in humans and rodents in effort to reduce the occurrence of these lethal infections in humans ...

Last Updated: 31 Dec 1969

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A Fatal Hantavirus Pulmonary Syndrome Misdiagnosed as Dengue: An Investigation into the First Reported Case in Rio de Janeiro State, Brazil.
 

Author(s): Renata Carvalho de Oliveira, Alexandro Guterres, Bernardo Rodrigues Teixeira, Jorlan Fernandes, João Marcos Penna Júnior, Reynaldo de Jesus Oliveira Júnior, Liana Strecht Pereira, João Bosco Júnior, Patrícia Soares Meneguete, Cristina Maria Giordano Dias, Cibele Rodrigues Bonvicino, Paulo Sérgio D'Andrea, Elba Regina Sampaio de Lemos

Journal: Am. J. Trop. Med. Hyg.. 2017 Jul;97(1):125-129.

 

We report the results of an investigation into a fatal case of hantavirus pulmonary syndrome (HPS) in Rio de Janeiro State, Brazil, where the disease had not been reported previous to 2015. Following the notification of an HPS case, serum samples were collected from the household ...

Last Updated: 31 Dec 1969

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Hantavirus pulmonary syndrome in Tucumán province associated to an unexpected viral genotype.
 

Author(s): Matías Ciancaglini, Carla M Bellomo, Clara L Torres Cabreros, Daniel Alonso, Sabrina C Bassi, Ayelén A Iglesias, Valeria P Martínez

Journal: Medicina (B Aires). 2017 ;77(2):81-84.

 

We describe the characterization of the viral genotype involved in the first case of hantavirus pulmonary syndrome reported in Tucumán, a Northwestern province of Argentina. A 23-year-old woman, with no record of travel history and previously diagnosed with an antiphospholipid syndrome, ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hantavirus Pulmonary Syndrome" returned 8 free, full-text review articles on human participants. First 3 results:

Twenty years of hantavirus pulmonary syndrome in Brazil: a review of epidemiological and clinical aspects.
 

Author(s): Vitor Laerte Pinto Junior, Amani Moura Hamidad, Dalcy de Oliveira Albuquerque Filho, Vitorino Modesto dos Santos

Journal:

 

Hantavirus infection is transmitted to humans by wild rodents and the most common clinical form in Brazil is the Hantavirus Pulmonary Syndrome (HPS). The first serological evidence of the disease was identified in 1990, in Recife, Pernambuco State, and later in 1993 in Juquitiba, ...

Last Updated: 31 Dec 1969

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The role of endothelial activation in dengue hemorrhagic fever and hantavirus pulmonary syndrome.
 

Author(s): Christina F Spiropoulou, Anon Srikiatkhachorn

Journal: Virulence. 2013 Aug;4(6):525-36.

 

The loss of the endothelium barrier and vascular leakage play a central role in the pathogenesis of hemorrhagic fever viruses. This can be caused either directly by the viral infection and damage of the vascular endothelium, or indirectly by a dysregulated immune response resulting ...

Last Updated: 31 Dec 1969

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The Syrian hamster model of hantavirus pulmonary syndrome.
 

Author(s): David Safronetz, Hideki Ebihara, Heinz Feldmann, Jay W Hooper

Journal: Antiviral Res.. 2012 Sep;95(3):282-92.

 

Hantavirus pulmonary syndrome (HPS) is a relatively rare, but frequently fatal disease associated with New World hantaviruses, most commonly Sin Nombre and Andes viruses in North and South America, respectively. It is characterized by fever and the sudden, rapid onset of severe respiratory ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Andes Virus DNA Vaccine for the Prevention of Hantavirus Pulmonary Syndrome Using the PharmaJet Stratis Needle-Free Injection Delivery Device
 

Status: Not yet recruiting

Condition Summary: Hantavirus Pulmonary Infection; Immunisation

 

Last Updated: 8 Nov 2018

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Diagnostic of Puumala Virus Infection in France
 

Status: Recruiting

Condition Summary: Nephropathia Epidemica; Hemorrhagic Fever With Renal Syndrome

 

Last Updated: 14 Aug 2018

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Combination HTNV and PUUV DNA Vaccine
 

Status: Not yet recruiting

Condition Summary: Hantaan Virus Disease, Puumala Virus

 

Last Updated: 7 Nov 2018

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