Heart Defects

Common Name(s)

Heart Defects

Congenital heart defects are problems with the heart’s structure that are present at birth. These problems may affect the overall shape of the heart, the heart’s valves, and the arteries and veins that carry blood to the heart or the body. Congenital heart defects affect 8 out of every 1,000 newborns, and more than 35,000 babies in the United States are born with a heart defect. Although the exact causes are unknown, heart defects may be linked to heredity factors, other genetic disorders (i.e. Down syndrome), and smoking during pregnancy. Severity ranges from defects with no symptoms to life-threatening defects. Many heart defects are easily fixed, although the more serious ones require attention throughout a person’s lifetime. Diagnosis may include a physical examination, X-rays, or various heart function tests. Defects can be treated with medication, surgery or through minimally invasive catheter procedures. In such procedures, a needle is used to insert a catheter into a vein or artery to repair the defect.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Heart Defects" for support, advocacy or research.

Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

Last Updated: 4 May 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Heart Defects" for support, advocacy or research.

Kids with Heart National Association for Children's Heart Disorders

Our organization was formed in 1985 with the main mission of providing support, information, resources, and education for the families of the children living with congenital heart defects and to promote public awareness of the issues that these families live with on a day to day basis.

http://www.kidswithheart.org

Last Updated: 4 May 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

General Resources

 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Heart Defects" returned 457 free, full-text research articles on human participants. First 3 results:

Maternal folic acid supplementation and dietary folate intake and congenital heart defects.
 

Author(s): Baohong Mao, Jie Qiu, Nan Zhao, Yawen Shao, Wei Dai, Xiaochun He, Hongmei Cui, Xiaojuan Lin, Ling Lv, Zhongfeng Tang, Sijuan Xu, Huang Huang, Min Zhou, Xiaoying Xu, Weitao Qiu, Qing Liu, Yawei Zhang

Journal:

 

It has been reported that folic acid supplementation before and/or during pregnancy could reduce the risk of congenital heart defects (CHDs). However, the results from limited epidemiologic studies have been inconclusive. We investigated the associations between maternal folic acid ...

Last Updated: 31 Dec 1969

Go To URL
Cost-effectiveness analysis of neonatal screening of critical congenital heart defects in China.
 

Author(s): Ruoyan Gai Tobe, Gerard R Martin, Fuhai Li, Akinori Moriichi, Bin Wu, Rintaro Mori

Journal: Medicine (Baltimore). 2017 Nov;96(46):e8683.

 

Pulse oximetry screening is a highly accurate tool for the early detection of critical congenital heart disease (CCHD) in newborn infants. As the technique is simple, noninvasive, and inexpensive, it has potentially significant benefits for developing countries. The aim of this study ...

Last Updated: 31 Dec 1969

Go To URL
Collaborative Quality Improvement in the Congenital Heart Defects: Development of the ASSIST Consortium and a Preliminary Surgical Outcomes Report.
 

Author(s): Fabio Carmona, Paulo Henrique Manso, Mariana Nicoletti Ferreira, Nana Miura Ikari, Marcelo Biscegli Jatene, Luciana Amato, Aida Luiza Turquetto, Luiz Fernando Caneo

Journal: Braz J Cardiovasc Surg. ;32(4):260-269.

 

ASSIST is the first Brazilian initiative in building a collaborative quality improvement program in pediatric cardiology and congenital heart disease. The purposes of this manuscript are: (a) to describe the development of the ASSIST project, including the historical, philosophical, ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Heart Defects" returned 45 free, full-text review articles on human participants. First 3 results:

Neighborhood Deprivation and Risk of Congenital Heart Defects, Neural Tube Defects and Orofacial Clefts: A Systematic Review and Meta-Analysis.
 

Author(s): Séverine Deguen, Wahida Kihal, Maxime Jeanjean, Cindy Padilla, Denis Zmirou-Navier

Journal:

 

We conducted this systematic review and meta-analysis to address the open question of a possible association between the socioeconomic level of the neighborhoods in which pregnant women live and the risk of Congenital Heart Defects (CHDs), Neural Tube Defects (NTDs) and OroFacial Clefts (OFCs).

Last Updated: 31 Dec 1969

Go To URL
[Review of epidemiological studies on individual and environmental risk factors in the aetiology of congenital heart defects].
 

Author(s): Silvia Baldacci, Francesca Gorini, Fabrizio Minichilli, Anna Pierini, Michele Santoro, Fabrizio Bianchi

Journal: Epidemiol Prev. ;40(3-4):185-96.

 

among all congenital malformations, congenital heart defects (CHDs) are the main cause of neonatal mortality and infant mortality and morbidity, thus representing a major public health burden. Several epidemiological studies suggested the role of environmental factors in the genesis of CHDs.

Last Updated: 31 Dec 1969

Go To URL
Xenopus as a model organism for birth defects-Congenital heart disease and heterotaxy.
 

Author(s): Anna R Duncan, Mustafa K Khokha

Journal: Semin. Cell Dev. Biol.. 2016 Mar;51():73-9.

 

Congenital heart disease is the leading cause of birth defects, affecting 9 out of 1000 newborns each year. A particularly severe form of congenital heart disease is heterotaxy, a disorder of left-right development. Despite aggressive surgical management, patients with heterotaxy ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Neurodevelopment in Infants With Complex Congenital Heart Defects
 

Status: Recruiting

Condition Summary: Complex Congenital Heart Defect

 

Last Updated: 3 Apr 2017

Go to URL
Electro-acupuncture (EA) in Children Undergoing Procedures for Congenital Heart Defects.
 

Status: Recruiting

Condition Summary: Congenital Heart Defect

 

Last Updated: 15 Nov 2017

Go to URL
Molecular Genetics of Heterotaxy and Related Congenital Heart Defects
 

Status: Recruiting

Condition Summary: Heterotaxy Syndrome; Congenital Heart Defects

 

Last Updated: 22 Aug 2017

Go to URL