Hemangioendothelioma

Common Name(s)

Hemangioendothelioma

The term hemangioendothelioma describes several types of vascular neosplasms and includes both non-cancerous (benign) and cancerous (malignant) growths. The term has also been applied to those that show "borderline" behavior, intermediate between entirely benign hemangiomas and highly malignant angiosarcomas. Hemangioendotheliomas are caused by abnormal growth of blood vessel cells, although the exact underlying cause for the abnormal growth is unknown. They can also develop in an organ, such as the liver or lung. They usually grow slowly and can sometimes spread to other tissues in the body (metastasize). Examples of types of hemangioendotheliomas include spindle cell hemangioma; papillary intralymphatic (Dabska tumor); retiform; kaposiform; epithelioid; pseudomyogenic (epithelioid sarcoma-like hemangioendothelioma); and composite. Treatment depends on the type of hemangioendothelioma present but typically includes surgical excision (removal).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioendothelioma" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hemangioendothelioma" returned 185 free, full-text research articles on human participants. First 3 results:

Intravascular epithelioid hemangioendothelioma of the femoral vein diagnosed by contrast-enhanced ultrasonography: A care-compliant case report.
 

Author(s): Luying Gao, Yahong Wang, Yuxin Jiang, Xingjian Lai, Ming Wang, Jianchu Li

Journal: Medicine (Baltimore). 2017 Dec;96(49):e9107.

 

Intravascular epithelioid hemangioendothelioma (EHE) is a rare endothelial tumor with an intermediate grade of malignancy. We present a case of one woman affected by EHE of the femoral vein. Contrast-enhanced ultrasonography played a role in diagnosing EHE and helped differentiate ...

Last Updated: 31 Dec 1969

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Apatinib for the treatment of pulmonary epithelioid hemangioendothelioma: A case report and literature review.
 

Author(s): Zhipeng Zheng, Hanying Wang, Hanliang Jiang, Enguo Chen, Jun Zhang, Xinyou Xie

Journal: Medicine (Baltimore). 2017 Nov;96(45):e8507.

 

Pulmonary epithelioid hemangioendothelioma (P-EHE) is a rare tumor, with no established standard treatment. Overexpression of vascular endothelial growth factor receptor 2 (VEGFR-2) has been reported in some P-EHE patients. Apatinib, a new small molecule tyrosine kinase inhibitor ...

Last Updated: 31 Dec 1969

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Intestinal obstruction due to kaposiform hemangioendothelioma in a 1-month-old infant: A case report.
 

Author(s): Joong Kee Youn, Shin-Hoo Park, Ji-Won Han, Chaeyoun Oh, Hyun-Young Kim, Sung-Eun Jung

Journal: Medicine (Baltimore). 2017 Sep;96(37):e6974.

 

Kaposiform hemangioendothelioma (KHE) is an aggressive vascular tumor, mainly occurring in infants and young children and previously reported cases were mainly cutaneous or visceral form. Intestinal kaposiform hemangioma was first reported in 2012. Intestinal type KHE showed better ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hemangioendothelioma" returned 25 free, full-text review articles on human participants. First 3 results:

Spontaneous rupture of hepatic epithelioid hemangioendothelioma: A case report.
 

Author(s): Jun-Wu Yang, Yong Li, Kai Xie, Wei Dong, Xian-Tong Cao, Wei-Dong Xiao

Journal: World J. Gastroenterol.. 2017 Jan;23(1):185-190.

 

Hepatic epithelioid hemangioendothelioma (HEH) is a rare tumor of vascular endothelial origin. Spontaneous rupture of HEH is a life-threatening complication and is extremely rare. HEH has variable malignant potential, and the clinical diagnosis remains challenging. Here we report ...

Last Updated: 31 Dec 1969

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Recurrence of Epithelioid Hemangioendothelioma during Pregnancy: Case Report and Systematic Review.
 

Author(s): Michael Mcculloch, Michael Russin, Arian Nachat

Journal: Perm J. 2016 ;20(3):84-9.

 

Epithelioid hemangioendothelioma (EHE) is a family of blood vessel tumors originating in blood vessels, bone, brain, kidney, liver, and lung. EHE is more common in women, and chemotherapy, radiation, and surgery have brought few successes.

Last Updated: 31 Dec 1969

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Treatment of kaposiform hemangioendothelioma and tufted angioma.
 

Author(s): Xiao Han Liu, Jia Ying Li, Xin Hua Qu, Wei Li Yan, Ling Zhang, Chi Yang, Jia Wei Zheng

Journal: Int. J. Cancer. 2016 10;139(7):1658-66.

 

This meta-analysis was to evaluate the efficacy of current treatment modalities for kaposiform hemangioendothelioma and tufted angioma. A systematic review was performed using PubMed (Medline), Web of Science and Embase for clinical studies. The outcome was measured by pooled response ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 9 Feb 2018

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Eribulin in Angiosarcoma and Epithelioid Hemangioendothelioma (EHE)
 

Status: Recruiting

Condition Summary: Angiosarcoma; Epithelioid Hemangioendothelioma

 

Last Updated: 26 Jan 2018

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Sirolimus Versus Sirolimus Plus Prednisolone for Kaposiform Hemangioendothelioma With Kasabach-Merritt Syndrome
 

Status: Recruiting

Condition Summary: Kaposiform Hemangioendothelioma; Kasabach Merritt Phenomenon

 

Last Updated: 15 Jun 2017

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