Hemangioma

Common Name(s)

Hemangioma

A hemangioma is a noncancerous clumping of blood vessels found on the skin or internal organs, most commonly the liver. Hemangiomas are often present at birth or develop in the first few months of life. Skin hemangiomas are quite common, mostly found on the face and neck. Liver hemangiomas rarely cause symptoms. Cavernous hemangiomas most commonly form on the brain or spinal cord and have a different outcome than the other types of hemangiomas. The cause of the clumping of the blood vessels is not well understood.

Skin hemangiomas form on the surface of the skin or in the fatty layer just underneath. It may at first appear as a flat birth mark, but will become a raised red rubbery or spongy lump over the first year. Most will stop growing at this point and after some time will begin to go away. Most skin hemangiomas disappear by age 10, though a faint discoloration may remain. Hemangiomas may affect the vision if they are on the eyelid.

Liver hemangiomas can form within the organ or on its surface. Liver hemangiomas may be estrogen sensitive, meaning they may grow if a woman is given estrogen supplements during menopause. Hemangiomas may also form on the kidneys, colon, and lungs. A hemangioma on any of these organs rarely causes problems unless it grows too large or multiple hemangiomas form. Symptoms may then include nausea, vomiting, abdominal pain, and loss of appetite. Occasionally they interfere with breathing. However, they usually go unnoticed unless picked up by an imaging study (MRI) being done for another reason.

Diagnosis is made by physical exam and imaging studies. Many hemangiomas will go away without treatment. If causing problems, treatment may include laser procedures, steroid injections, medication or surgical removal. If you or your child has been diagnosed with hemangioma, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioma" for support, advocacy or research.

VHL Alliance

VHLA is dedicated to research, education, and support to improve awareness, diagnosis, treatment, and quality of life for those affected by VHL.

Last Updated: 5 Jan 2015

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemangioma" for support, advocacy or research.

VHL Alliance

VHLA is dedicated to research, education, and support to improve awareness, diagnosis, treatment, and quality of life for those affected by VHL.

http://www.vhl.org

Last Updated: 5 Jan 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hemangioma" returned 706 free, full-text research articles on human participants. First 3 results:

Jagged1/Notch3 Signaling Modulates Hemangioma-Derived Pericyte Proliferation and Maturation.
 

Author(s): Yi Ji, Siyuan Chen, Bo Xiang, Yuan Li, Li Li, Qi Wang

Journal: Cell. Physiol. Biochem.. 2016 ;40(5):895-907.

 

The Notch signaling pathway has been implicated in the pericyte phenotype, but its exact roles in hemangioma-derived pericytes (Hem-pericytes) remain ill defined.

Last Updated: 12 Dec 2016

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A Symptomatic Case of Thoracic Vertebral Hemangioma Causing Lower Limb Spastic Paresis.
 

Author(s): Mohammad Alfawareh, Tariq Alotaibi, Abdallah Labeeb, Ziad Audat

Journal:

 

BACKGROUND Despite being the most common tumor of the spine, vertebral hemangioma is rarely symptomatic in adults. In fact, only 0.9-1.2% of all vertebral hemangiomas may be symptomatic. When hemangiomas occur in the thoracic vertebrae, they are more likely to be symptomatic due to ...

Last Updated: 31 Oct 2016

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Review of renal anastomosing hemangioma with focus on clinical and pathological aspects.
 

Author(s): N Kuroda, C Ohe, S Deepika, K Yorita, S Mikami, M Furuya, Y Nagashima, O Hes, A Agaimy, M Michal, M B Amin

Journal: Pol J Pathol. 2016 Jun;67(2):97-101.

 

Renal anastomosing hemangiomas (RAH) has been recently proposed as a new entity. In this article, we summarize the clinicopathologic features of this tumor. RAH usually develops on a background of end-stage renal disease. Macroscopically, tumors are well-defined and their cut surface ...

Last Updated: 21 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hemangioma" returned 77 free, full-text review articles on human participants. First 3 results:

Anastomosing hemangioma: report of two renal cases and analysis of the literature.
 

Author(s): Marina Perdiki, Galateia Datseri, George Liapis, Nikolaos Chondros, Ioannis Anastasiou, Maria Tzardi, Johanna K Delladetsima, Elias Drakos

Journal:

 

Anastomosing hemangioma (AH) is a very rare vascular tumor mimicking angiosarcoma, predominately observed in kidney and less frequently in other organs. We present two new renal cases of AH at opposite ends of the clinical presentation spectrum, provide review of the literature and ...

Last Updated: 25 Jan 2017

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Lobular capillary hemangioma of the tracheobronchial tree: A case report and literature review.
 

Author(s): Xiaojian Qiu, Zhiwu Dong, Jie Zhang, Jin Yu

Journal: Medicine (Baltimore). 2016 Nov;95(48):e5499.

 

Lobular capillary hemangioma (LCH) of the tracheobronchial tree is a rare benign tumor, whose characteristics and treatments remain relatively unknown.

Last Updated: 30 Nov 2016

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Urethral hemangioma: case report and review of the literature.
 

Author(s): Souhail Regragui, Amine Slaoui, Tarik Karmouni, Khalid El Khader, Abdelatif Koutani, Ahmed Ibn Attya

Journal:

 

Hemangiomas are benign vascular tumors. They are the prerogative of the liver and skin. And genitourinary localizations are rare and have only been rarely reported in the prostat, bladder, ureter or the perineum. In the light of published cases, urethral hemangiomas are mostly found ...

Last Updated: 27 May 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Nadolol Versus Propranolol in Children With Infantile Hemangiomas
 

Status: Recruiting

Condition Summary: Infantile Hemangioma

 

Last Updated: 4 Jan 2016

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Efficacy, Safety and Pharmacokinetics of Topical Timolol in Infants With Infantile Hemangioma (IH)
 

Status: Not yet recruiting

Condition Summary: Infantile Hemangioma

 

Last Updated: 21 Sep 2016

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