Hemophilic arthropathy

Common Name(s)

Hemophilic arthropathy

Hemophilic arthropathy is a condition characterized by permanent joint disease associated with hemophilia, a disorder that results in excessive bleeding. Hemophilia may sometimes result in bleeding into the joint space, or hemarthrosis, which may cause damage to the joint. Around 50% of people with hemophilia develop hemophilic arthropathy. The knees, ankles, elbows, hip and shoulders are most commonly involved. Symptoms of hemophilic arthropathy include joint pain, swelling, and difficulty moving joints. A physician can use blood tests to diagnose hemophila and can use a physical exam and x-rays to diagnose hemophila arthropathy. If the condition is caught early, blood infusions can prevent or delay joint destruction. If the joint damage is severe, joint replacement surgery may be necessary.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hemophilic arthropathy" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hemophilic arthropathy" returned 11 free, full-text research articles on human participants. First 3 results:

Soluble vascular cell adhesion molecular-1 is a potential biological indicator of hemophilic arthropathy.
 

Author(s): Yu-Hsin Tseng, Shyh-Shin Chiou, Yu-Sheng Zeng, Shih-Pien Tsai, Chun-Shih Chen, Yu-Mei Liao, Pei-Chin Lin

Journal: Medicine (Baltimore). 2016 Nov;95(46):e5384.

 

Hemophilic arthropathy is the most common chronic complication in patients with hemophilia. The pathogenesis of hemophilic arthropathy involves the inflammatory processes associated with rheumatoid arthritis (RA). Determining the severity and/or progression of joint damage is crucial ...

Last Updated: 18 Nov 2016

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Inflammation is key to hemophilic arthropathy.
 

Author(s): Alok Srivastava

Journal: Blood. 2015 Nov;126(19):2175-6.

 

Last Updated: 6 Nov 2015

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Vascular remodeling underlies rebleeding in hemophilic arthropathy.
 

Author(s): Vikas Bhat, Merissa Olmer, Shweta Joshi, Donald L Durden, Thomas J Cramer, Richard Fw Barnes, Scott T Ball, Tudor H Hughes, Mauricio Silva, James V Luck, Randy E Moore, Laurent O Mosnier, Annette von Drygalski

Journal: Am. J. Hematol.. 2015 Nov;90(11):1027-35.

 

Hemophilic arthropathy is a debilitating condition that can develop as a consequence of frequent joint bleeding despite adequate clotting factor replacement. The mechanisms leading to repeated spontaneous bleeding are unknown. We investigated synovial, vascular, stromal, and cartilage ...

Last Updated: 21 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hemophilic arthropathy" returned 2 free, full-text review articles on human participants. First 3 results:

Advances and challenges in hemophilic arthropathy.
 

Author(s): Tine Wyseure, Laurent O Mosnier, Annette von Drygalski

Journal: Semin. Hematol.. 2016 Jan;53(1):10-9.

 

Hemophilic arthropathy is a form of joint disease that develops secondary to joint bleeding and presents with synovial hypertrophy, cartilage and bony destruction. The arthropathy can develop despite clotting factor replacement and is especially disabling in the aging population. ...

Last Updated: 25 Jan 2016

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Blood-induced joint disease: the pathophysiology of hemophilic arthropathy.
 

Author(s): L A Valentino

Journal: J. Thromb. Haemost.. 2010 Sep;8(9):1895-902.

 

Arthropathy is a frequent and serious complication of repeated joint bleeding in patients with hemophilia, resulting in pain, deformity, and disability. Although the pathogenesis of hemophilic arthropathy has not been fully elucidated, it appears to have similarities with the degenerative ...

Last Updated: 28 Oct 2010

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 13 Dec 2016

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Efficacy and Safety of Shea Nut Oil in Hemophilic Arthropathy
 

Status: Recruiting

Condition Summary: Hemophilia; Hemophilic Arthropathy

 

Last Updated: 9 Nov 2016

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Myofascial Therapy in Patients With Hemophilic Arthropathy
 

Status: Recruiting

Condition Summary: Hemophilia

 

Last Updated: 13 Oct 2015

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