Hepatitis B

Common Name(s)

Hepatitis B

Hepatitis B is a viral hepatitis that affects the liver and is caused by the hepatitis B virus, or HBV. The liver is an organ found on the right side of our belly (abdomen) under the rib cage. It cleans our blood of toxins, poisons, and bacteria. It produces bile which helps our body breakdown food. Hepatitis B occurs when HBV causes a person’s immune system to attack the liver. Symptoms may be mild to severe and may include nausea, diarrhea, fatigue, and jaundice (yellowing of the skin). Usually the body is able to fight the infection within 6 months (acute infection). Chronic HBV infections may lead to liver cancer, permanent scarring of the liver (cirrhosis), or liver failure. It is rare for HBV to become chronic in adults, but 80% of infected newborns and 20% of infected children under 5 develop a chronic infection. HBV is spread from person to person through blood, semen or other body fluids. The most common ways to get infected by HBV are through sexual contact with someone who has HBV, sharing of infected needles (usually during IV drug use), accidental needle sticks to health care workers working with patients who have HBV, and mother to child during childbirth if the mother has HBV.

A vaccine is available to prevent HBV infection. The vaccine may even be given to newborns exposed to HBV during childbirth to successfully prevent infection. It is important to call your physician within 12 hours if you know you have been exposed to HBV and are not vaccinated. There are treatments available to decrease your chance of becoming infected. If the condition becomes chronic, there are medications available to help slow the damage to the liver but there is no cure at this time. HBV infections are diagnosed through blood tests and possibly liver biopsies. Talk with your doctor if you or a family member has been diagnosed with hepatitis B. Support groups are also good resources of support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis B" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

Last Updated: 11 Jul 2016

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

Last Updated: 15 Apr 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis B" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

http://www.thestdproject.com/

Last Updated: 11 Jul 2016

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

http://www.worldhepatitisalliance.org/en/

Last Updated: 15 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatitis B" returned 8447 free, full-text research articles on human participants. First 3 results:

Molecular characterization of hepatitis B virus in Bangladesh reveals a highly recombinant population.
 

Author(s): Saif Ullah Munshi, Thanh Thi Thanh Tran, Truc Nhu Thanh Vo, Shahina Tabassum, Nahida Sultana, Trang Hoa Nguyen, Munira Jahan, Chau Ngoc Le, Stephen Baker, Motiur Rahman

Journal:

 

The natural history and treatment outcome of hepatitis B viruses (HBV) infection is largely dependent on genotype, subgenotype, and the presence or absence of virulence associated mutations. We have studied the prevalence of genotype and subgenotype as well as virulence and drug resistance ...

Last Updated: 31 Dec 1969

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A multi-scale spatial model of hepatitis-B viral dynamics.
 

Author(s): Quentin Cangelosi, Shawn A Means, Harvey Ho

Journal:

 

Chronic hepatitis B viral infection (HBV) afflicts around 250 million individuals globally and few options for treatment exist. Once infected, the virus entrenches itself in the liver with a notoriously resilient colonisation of viral DNA (covalently-closed circular DNA, cccDNA). ...

Last Updated: 31 Dec 1969

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Naringenin attenuates hepatitis B virus X protein-induced hepatic steatosis.
 

Author(s): Hung-Jen Lin, Ko-Li Ku, I-Hsin Lin, Chia-Chou Yeh

Journal:

 

Naringenin (Nar), a common dietary flavonoid abundantly present in fruits, vegetables, and Chinese herbs, is believed to possess strong anti-inflammatory properties and to modulate hepatic apolipoprotein and lipid synthesis. However, there are no reports describing Nar's effects on ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatitis B" returned 860 free, full-text review articles on human participants. First 3 results:

Comparison of diagnostic accuracy of magnetic resonance elastography and Fibroscan for detecting liver fibrosis in chronic hepatitis B patients: A systematic review and meta-analysis.
 

Author(s): Huanming Xiao, Meijie Shi, Yubao Xie, Xiaoling Chi

Journal:

 

This systematic review and meta-analysis was carried out to compare the diagnostic accuracy of Magnetic resonance elastography (MRE) and Fibroscan for detecting liver fibrosis in Chronic Hepatitis B (CHB) patients.

Last Updated: 31 Dec 1969

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Current prevalence of chronic hepatitis B and C virus infection in the general population, blood donors and pregnant women in the EU/EEA: a systematic review.
 

Author(s): S H I Hofstraat, A M Falla, E F Duffell, S J M Hahné, A J Amato-Gauci, I K Veldhuijzen, L Tavoschi

Journal: Epidemiol. Infect.. 2017 10;145(14):2873-2885.

 

This systematic review aimed at estimating chronic hepatitis B (HBV) and C virus (HCV) prevalence in the European Union (EU) and Economic Area (EEA) countries in the general population, blood donors and pregnant women. We searched PubMed©, Embase© and Cochrane Library databases ...

Last Updated: 31 Dec 1969

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Dermatomyositis Induced by Hepatitis B Virus-related Hepatocellular Carcinoma: A Case Report and Review of the Literature.
 

Author(s): Jen-Wei Chou, Yin-Lan Lin, Ken-Sheng Cheng, Po-Yuan Wu, Teressa Reanne Ju

Journal: Intern. Med.. 2017 ;56(14):1831-1837.

 

Dermatomyositis or polymyositis as a paraneoplastic syndrome of hepatocellular carcinoma (HCC) is an uncommon event. Few cases have been reported in the literature. We herein report the case of a 55-year-old man with chronic hepatitis B and alcoholism who presented with skin rash. ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Tenofovir in Early Pregnancy to Prevent Mother-to-child Transmission of Hepatitis B Virus
 

Status: Not yet recruiting

Condition Summary: Hepatitis B

 

Last Updated: 16 Jan 2018

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Hepatitis B Prevalence in the Turkish Population Living in Middle Limburg
 

Status: Recruiting

Condition Summary: Hepatitis B

 

Last Updated: 9 Jan 2018

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Ledipasvir/Sofosbuvir for Hepatitis B Virus Infection
 

Status: Not yet recruiting

Condition Summary: Hepatitis B

 

Last Updated: 17 Jan 2018

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