Hepatitis B

Common Name(s)

Hepatitis B

Hepatitis B is a viral hepatitis that affects the liver and is caused by the hepatitis B virus, or HBV. The liver is an organ found on the right side of our belly (abdomen) under the rib cage. It cleans our blood of toxins, poisons, and bacteria. It produces bile which helps our body breakdown food. Hepatitis B occurs when HBV causes a person’s immune system to attack the liver. Symptoms may be mild to severe and may include nausea, diarrhea, fatigue, and jaundice (yellowing of the skin). Usually the body is able to fight the infection within 6 months (acute infection). Chronic HBV infections may lead to liver cancer, permanent scarring of the liver (cirrhosis), or liver failure. It is rare for HBV to become chronic in adults, but 80% of infected newborns and 20% of infected children under 5 develop a chronic infection. HBV is spread from person to person through blood, semen or other body fluids. The most common ways to get infected by HBV are through sexual contact with someone who has HBV, sharing of infected needles (usually during IV drug use), accidental needle sticks to health care workers working with patients who have HBV, and mother to child during childbirth if the mother has HBV.

A vaccine is available to prevent HBV infection. The vaccine may even be given to newborns exposed to HBV during childbirth to successfully prevent infection. It is important to call your physician within 12 hours if you know you have been exposed to HBV and are not vaccinated. There are treatments available to decrease your chance of becoming infected. If the condition becomes chronic, there are medications available to help slow the damage to the liver but there is no cure at this time. HBV infections are diagnosed through blood tests and possibly liver biopsies. Talk with your doctor if you or a family member has been diagnosed with hepatitis B. Support groups are also good resources of support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis B" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

Last Updated: 11 Jul 2016

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

Last Updated: 15 Apr 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis B" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

http://www.thestdproject.com/

Last Updated: 11 Jul 2016

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

http://www.worldhepatitisalliance.org/en/

Last Updated: 15 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatitis B" returned 8854 free, full-text research articles on human participants. First 3 results:

Different interventional criteria for chronic hepatitis B pregnant women with HBeAg(+) or HBeAg(-): Epidemiological data from Shaanxi, China.
 

Author(s): Tianyan Chen, Jing Wang, Hongtao Qiu, Qiang Yu, Taotao Yan, Caijing Qi, Furong Cao, Zhen Tian, Dandan Guo, Naijuan Yao, Yuan Yang, Yingli He, Yingren Zhao, Jinfeng Liu

Journal: Medicine (Baltimore). 2018 Jul;97(27):e11406.

 

The seroprevalence of hepatitis B virus (HBV) and its impact on pregnancy outcomes of women from Shaanxi Province (China) was assessed. Risk factors for mother-to-child transmission (MTCT) were evaluated based on HBV-related seroprevalence data.Viral markers and biochemical parameters ...

Last Updated: 31 Dec 1969

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Prevention of Hepatitis B Virus Infection in the United States: Recommendations of the Advisory Committee on Immunization Practices.
 

Author(s): Sarah Schillie, Claudia Vellozzi, Arthur Reingold, Aaron Harris, Penina Haber, John W Ward, Noele P Nelson

Journal:

 

HEPATITIS B VIRUS (HBV) IS TRANSMITTED VIA BLOOD OR SEXUAL CONTACT. PERSONS WITH CHRONIC HBV INFECTION ARE AT INCREASED RISK FOR CIRRHOSIS AND LIVER CANCER AND REQUIRE MEDICAL CARE. THIS REPORT UPDATES AND SUMMARIZES PREVIOUSLY PUBLISHED RECOMMENDATIONS FROM THE ADVISORY COMMITTEE ...

Last Updated: 31 Dec 1969

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Adalimumab therapy in hepatitis B virus-negative polyarteritis nodosa: A case report.
 

Author(s): Chrong-Reen Wang, Chao-Chun Yang

Journal: Medicine (Baltimore). 2018 Jun;97(25):e11053.

 

Polyarteritis nodosa (PAN) is a difficult-to-treat rheumatology disorder, and biologic agents have been used in such patients with a treatment failure or the disease relapse.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatitis B" returned 902 free, full-text review articles on human participants. First 3 results:

[Occult hepatitis B reactivation in a patient with homozygous sickle cell disease: clinical case and literature review].
 

Author(s): Moustapha Diop, Viviane Marie Pierre Cisse-Diallo, Daye Ka, Ndèye Aissatou Lakhe, Khardiata Diallo-Mbaye, Aminata Massaly, Alassane Dièye, Ndèye Maguette Fall, Aboubacar Sadikh Badiane, Daouda Thioub, Louise Fortes-Déguénonvo, Gora Lo, Cheikh Tacko Diop, Cheikh Tidiane Ndour, Masserigne Soumaré, Moussa Seydi

Journal:

 

Occult Hepatitis B corresponds to the presence of hepatitis B virus-deoxyribonucleic acid (HBV-DNA) in serum and/or in liver of a patient despite HBsAg negativity. Clinically, it is usually asymptomatic. Its reactivation is rare and commonly occurs in immunosuppressed individuals. ...

Last Updated: 31 Dec 1969

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Animal models for the study of hepatitis B virus infection.
 

Author(s): Wei-Na Guo, Bin Zhu, Ling Ai, Dong-Liang Yang, Bao-Ju Wang

Journal: Zool Res. 2018 Jan;39(1):25-31.

 

Even with an effective vaccine, an estimated 240 million people are chronically infected with hepatitis B virus (HBV) worldwide. Current antiviral therapies, including interferon and nucleot(s)ide analogues, rarely cure chronic hepatitis B. Animal models are very crucial for understanding ...

Last Updated: 31 Dec 1969

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Hepatitis B/C in the countries of the EU/EEA: a systematic review of the prevalence among at-risk groups.
 

Author(s): Abby May Falla, Sanne Henrietta Ina Hofstraat, Erika Duffell, Susan Josien Maria Hahné, Lara Tavoschi, Irene Karen Veldhuijzen

Journal:

 

In 2016, the World Health Organisation set a goal to eliminate viral hepatitis by 2030. Robust epidemiological information underpins all efforts to achieve elimination and this systematic review provides estimates of HBsAg and anti-HCV prevalence in the European Union/European Economic ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Tenofovir in Early Pregnancy to Prevent Mother-to-child Transmission of Hepatitis B Virus
 

Status: Not yet recruiting

Condition Summary: Hepatitis B

 

Last Updated: 17 Apr 2018

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Hepatitis B Vaccine for Non-responders
 

Status: Recruiting

Condition Summary: Hepatitis B

 

Last Updated: 9 Apr 2018

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Hepatitis B Prevalence in the Turkish Population Living in Middle Limburg
 

Status: Recruiting

Condition Summary: Hepatitis B

 

Last Updated: 9 Jan 2018

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