Hepatitis B

Common Name(s)

Hepatitis B

Hepatitis B is a viral hepatitis that affects the liver and is caused by the hepatitis B virus, or HBV. The liver is an organ found on the right side of our belly (abdomen) under the rib cage. It cleans our blood of toxins, poisons, and bacteria. It produces bile which helps our body breakdown food. Hepatitis B occurs when HBV causes a person’s immune system to attack the liver. Symptoms may be mild to severe and may include nausea, diarrhea, fatigue, and jaundice (yellowing of the skin). Usually the body is able to fight the infection within 6 months (acute infection). Chronic HBV infections may lead to liver cancer, permanent scarring of the liver (cirrhosis), or liver failure. It is rare for HBV to become chronic in adults, but 80% of infected newborns and 20% of infected children under 5 develop a chronic infection. HBV is spread from person to person through blood, semen or other body fluids. The most common ways to get infected by HBV are through sexual contact with someone who has HBV, sharing of infected needles (usually during IV drug use), accidental needle sticks to health care workers working with patients who have HBV, and mother to child during childbirth if the mother has HBV.

A vaccine is available to prevent HBV infection. The vaccine may even be given to newborns exposed to HBV during childbirth to successfully prevent infection. It is important to call your physician within 12 hours if you know you have been exposed to HBV and are not vaccinated. There are treatments available to decrease your chance of becoming infected. If the condition becomes chronic, there are medications available to help slow the damage to the liver but there is no cure at this time. HBV infections are diagnosed through blood tests and possibly liver biopsies. Talk with your doctor if you or a family member has been diagnosed with hepatitis B. Support groups are also good resources of support and information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis B" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

Last Updated: 27 Nov 2012

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

Last Updated: 11 Jul 2016

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

Last Updated: 15 Apr 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hepatitis B" for support, advocacy or research.

Hepatitis Foundation International

Hepatitis Foundation International is dedicated to promoting wellness and healthy lifestyles for all individuals in order to reduce the incidence of preventable diseases that affect the liver’s health including: obesity, diabetes, fatty liver, high cholesterol, cardiovascular disease, hepatitis, HIV/AIDS, and substance abuse. We inform, educate, and empower by making available reliable and up-to-date information.

http://www.HepatitisFoundation.org

Last Updated: 23 Feb 2015

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American Liver Foundation

The American Liver Foundation (ALF) is the nation's leading nonprofit organization promoting liver health and disease prevention. ALF provides research, education and advocacy for those affected by liver-related diseases, including hepatitis.

http://www.liverfoundation.org

Last Updated: 27 Nov 2012

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

http://www.thestdproject.com/

Last Updated: 11 Jul 2016

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World Hepatitis Alliance

The World Hepatitis Alliance is a not-for-profit international umbrella NGO. Our membership is composed of over 170 organisations who work in the field of viral hepatitis, representing every region of the world. We are patient-led and patient-driven, and in this way, we are the global voice for the 500 million people worldwide living with viral hepatitis. Through better awareness, prevention, care, support and access to treatment, our ultimate goal is to work with governments to eradicate these diseases from the planet.

http://www.worldhepatitisalliance.org/en/

Last Updated: 15 Apr 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hepatitis B" returned 8424 free, full-text research articles on human participants. First 3 results:

Hepatitis B virus infection in an HBsAb-positive lymphoma patient who received chemotherapy: A case report.
 

Author(s): Fu-Biao Kang, Ling Wang, Dian-Xing Sun

Journal: Medicine (Baltimore). 2017 Nov;96(44):e8518.

 

Tumor chemotherapy could weaken the immune system of patients, which might enhance the body sensitivities to the exogenous pathogens, among which the hepatitis B virus (HBV) infection should be concerned because of the higher chances of infection and the severe outcomes, especially ...

Last Updated: 2 Nov 2017

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Effective viral suppression is necessary to reduce hepatocellular carcinoma development in cirrhotic patients with chronic hepatitis B: Results of a 10-year follow up.
 

Author(s): Wei Zhang, Xiaoming Wang, Yu Wang, Xinyan Zhao, Weijia Duan, Qianyi Wang, Xiaoning Wu, Yuanyuan Kong, Hong Ma, Hong You, Xiaojuan Ou, Jidong Jia

Journal: Medicine (Baltimore). 2017 Nov;96(44):e8454.

 

High viral load is an independent risk factor for development of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB). Antiviral therapy can reduce but not eliminate the risk of HCC. The aim of this study was to identify the risk factors for HCC development in ...

Last Updated: 2 Nov 2017

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Pre-S deletions of hepatitis B virus predict recurrence of hepatocellular carcinoma after curative resection.
 

Author(s): Qu Li-Shuai, Chen Yu-Yan, Zhang Hai-Feng, Liu Jin-Xia, Lu Cui-Hua

Journal: Medicine (Baltimore). 2017 Oct;96(43):e8311.

 

The relationship between hepatitis B virus (HBV) and the prognosis of hepatocellular carcinoma (HCC) after surgery remains uncertain. A retrospective cohort study was performed to evaluate the impact of pre-S deletions, T1762/A1764, and A1896 mutations on prognosis of HCC after curative ...

Last Updated: 25 Oct 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hepatitis B" returned 858 free, full-text review articles on human participants. First 3 results:

Current prevalence of chronic hepatitis B and C virus infection in the general population, blood donors and pregnant women in the EU/EEA: a systematic review.
 

Author(s): S H I Hofstraat, A M Falla, E F Duffell, S J M Hahné, A J Amato-Gauci, I K Veldhuijzen, L Tavoschi

Journal: Epidemiol. Infect.. 2017 Oct;145(14):2873-2885.

 

This systematic review aimed at estimating chronic hepatitis B (HBV) and C virus (HCV) prevalence in the European Union (EU) and Economic Area (EEA) countries in the general population, blood donors and pregnant women. We searched PubMed©, Embase© and Cochrane Library databases ...

Last Updated: 11 Sep 2017

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Hepatitis B virus reactivation and antiviral prophylaxis during lung cancer chemotherapy: A systematic review and meta-analysis.
 

Author(s): Yu-Tuan Wu, Xin Li, Zi-Li Liu, Zhou Xu, Wei Dai, Ke Zhang, Jiu-Song Wu, Bilal Arshad, Kai-Nan Wu, Ling-Quan Kong

Journal:

 

Antiviral drugs have been recommended as prophylaxis for the reactivation of hepatitis B virus (HBV) infection in cancer patients undergoing chemotherapy. However, screening and antiviral prophylaxis for lung cancer remain controversial because of insufficient evidence.

Last Updated: 22 Jun 2017

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Spleen implanting in the fatty liver mimicking hepatocarcinoma in a patient with hepatitis B&C: A case report and literature review.
 

Author(s): Meng-Yao Wang, Bao Li, Dan Chen, Ai-Lian Liu, Sahrish Qamar, Mei-Yu Sun

Journal: Medicine (Baltimore). 2017 Jun;96(25):e7217.

 

Ectopic splenic autotransplantation refers to the heterotopic autotransplantation of splenic tissue and no treatment is necessary for it when patient is asymptomatic. Its incidence rate is reported up to 67% among patients with a history of splenic trauma and splenic surgery. The ...

Last Updated: 22 Jun 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Hepatitis B Research Network Pediatric Cohort Study (HBRN)
 

Status: Recruiting

Condition Summary: Hepatitis B

 

Last Updated: 26 Sep 2017

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TDF Medicine to Prevent Mother to Child Transmission of Hepatitis B
 

Status: Not yet recruiting

Condition Summary: Hepatitis B

 

Last Updated: 23 May 2017

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Hepatitis B Research Network Adult Cohort Study
 

Status: Recruiting

Condition Summary: Hepatitis B

 

Last Updated: 26 Sep 2017

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