Hereditary gingival fibromatosis

Common Name(s)

Hereditary gingival fibromatosis

Gingival fibromatosis is a rare overgrowth condition characterized by a benign, slowly progressive, nonhemorrhagic, fibrous enlargement of maxillary and mandibular keratinized gingiva (summary by {7:Hart et al., 2002}). Genetic Heterogeneity of Hereditary Gingival Fibromatosis Other loci for gingival fibromatosis have been mapped to chromosome 5q (GINGF2; {605544}), chromosome 2p23.3-p22.3 (GINGF3; {609955}), and chromosome 11p15 (GINGF4; {611010}). GINGF5 ({617626}) is caused by mutation in the REST gene ({600571}) on chromosome 4q12. There is some evidence for a locus on chromosome 2p16-p13 (see MAPPING).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hereditary gingival fibromatosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hereditary gingival fibromatosis" returned 13 free, full-text research articles on human participants. First 3 results:

Hereditary gingival fibromatosis: clinical and ultrastructural features of a new family.
 

Author(s): Sabina-Pena-Borges Pego, Ricardo D Coletta, Danilo-Cangussu Mendes, Paulo-Rogério de Faria, Mário R Melo-Filho, Lucas-Rodrigues Alves, Hercílio Martelli-Júnior

Journal:

 

This article describes the diagnosis, clinical and microscopic (histopathology and ultrastructural) features and treatment of a new family with hereditary gingival fibromatosis (HGF) and highlights the importance of this genetic condition.

Last Updated: 2 Mar 2015

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In vitro testing the potential of a novel chimeric IgG variant for inhibiting collagen fibrils formation in recurrent hereditary gingival fibromatosis: chimeric antibody in a gingival model.
 

Author(s): K Gawron, K Lazarz-Bartyzel, M Lazarz, K Steplewska, K Pyrc, J Potempa, M Chomyszyn-Gajewska

Journal: J. Physiol. Pharmacol.. 2014 Aug;65(4):585-91.

 

Gingival fibromatosis is a progressive enlargement of the gingiva. It may hinder oral cavity hygiene and result in underlying bone loss. The long-term benefits of surgery cannot be predicted. On the other hand, alternative, efficient and non-invasive methods are not available at present. ...

Last Updated: 2 Sep 2014

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Non-syndromic hereditary gingival fibromatosis.
 

Author(s): Ravi Prakash Sasankoti Mohan, Sankalp Verma, Neha Agarwal, Udita Singh

Journal:

 

Hereditary gingival fibromatosis is a rare condition characterised by severe gingival hyperplasia that can occur as an isolated disease or as part of a syndrome or chromosomal abnormality. In severe cases, the gingival enlargement may cover the crowns of teeth and cause severe aesthetic, ...

Last Updated: 13 Sep 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hereditary gingival fibromatosis" returned 0 free, full-text review articles on human participants.

 
 
 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

There are currently no open clinical trials for this condition.