Hidrotic ectodermal dysplasia syndrome

Common Name(s)

Hidrotic ectodermal dysplasia syndrome

The main features of Clouston syndrome are dystrophy of the nails that tend to be hypoplastic and deformed with increased susceptibility to paronychial infections, defects of the hair that range from brittleness and slow growth rate to total alopecia, and moderate to severe palmoplantar hyperkeratosis with reduced keratinocyte desquamation (summary by {13:Kibar et al., 1996}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hidrotic ectodermal dysplasia syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hidrotic ectodermal dysplasia syndrome" returned 2 free, full-text research articles on human participants. First 3 results:

Confirmation of linkage of Clouston syndrome (hidrotic ectodermal dysplasia) to 13q11-q12.1 with evidence for multiple independent mutations.
 

Author(s): T D Taylor, S J Hayflick, W McKinnon, A E Guttmacher, A Hovnanian, M Litt, J Zonana

Journal: J. Invest. Dermatol.. 1998 Jul;111(1):83-5.

 

Clouston syndrome (hidrotic ectodermal dysplasia) is an autosomal dominant disorder characterized by the triad of nail dystrophy, alopecia, and palmoplantar hyperkeratosis. Recently, linkage of a Clouston syndrome locus to chromosome 13q11-q12.1 was reported in eight families of French-Canadian ...

Last Updated: 24 Jul 1998

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Clouston syndrome (hidrotic ectodermal dysplasia) is not linked to keratin gene clusters on chromosomes 12 and 17.
 

Author(s): S J Hayflick, T Taylor, W McKinnon, A E Guttmacher, M Litt, J Zonana

Journal: J. Invest. Dermatol.. 1996 Jul;107(1):11-4.

 

Clouston syndrome is an hidrotic form of ectodermal dysplasia, inherited as an autosomal dominant trait with high penetrance. The main features of the disorder are alopecia, severe dystrophy of the nails, and palmoplantar hyperkeratosis. A molecular abnormality of keratin has long ...

Last Updated: 13 Dec 1996

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Reviews from the PubMed Database

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The terms "Hidrotic ectodermal dysplasia syndrome" returned 0 free, full-text review articles on human participants.

 
 
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