Perihilar cholangiocarcinoma

Common Name(s)

Perihilar cholangiocarcinoma, Klatskin tumor, Perihilar bile duct cancer, Hilar cholangiocarcinoma

Klatskin tumors are tumors that affect the upper part of the bile duct where it divides to enter the right and left parts of the liver. One or both sides may be affected. Individuals with Klatskin tumors often present with jaundice and/or abnormal liver tests. Treatment may involve surgical removal of the tumor. Not all tumors can be removed. Prognosis for cases that cannot be removed (non-resectable tumors) is poor.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Perihilar cholangiocarcinoma" for support, advocacy or research.

Logo
Cholangiocarcinoma Foundation

Our mission is to find a cure and improve the quality of life for those affected by cholangiocarcinoma

Last Updated: 1 May 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Perihilar cholangiocarcinoma" for support, advocacy or research.

Logo
Cholangiocarcinoma Foundation

Our mission is to find a cure and improve the quality of life for those affected by cholangiocarcinoma

http://www.cholangiocarcinoma.org

Last Updated: 1 May 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Perihilar cholangiocarcinoma" returned 44 free, full-text research articles on human participants. First 3 results:

Curative-intent Surgery for Perihilar Cholangiocarcinoma with and without Portal Vein Resection - A Comparative Analysis of Early and Late Outcomes.
 

Author(s): Traian Dumitraşcu, Cezar Stroescu, Vladislav Braşoveanu, Vlad Herlea, Mihnea Ionescu, Irinel Popescu

Journal: Chirurgia (Bucur). ;112(3):308-319.

 

The safety of portal vein resection (PVR) during surgery for perihilar cholangiocarcinoma (PHC) has been demonstrated in Asia, America, and Western Europe. However, no data about this topic are reported from Eastern Europe. The aim of the present study is to comparatively assess ...

Last Updated: 31 Dec 1969

Go To URL
A nomogram prediction of postoperative surgical site infections in patients with perihilar cholangiocarcinoma.
 

Author(s): Long Li, Jie Ding, Jun Han, Hong Wu

Journal: Medicine (Baltimore). 2017 Jun;96(25):e7198.

 

Surgical site infection (SSI) is one of the major morbidities after radical resection for perihilar cholangiocarcinoma (PHCC). This study aimed to clarify the risk factors and construct a nomogram to predict SSIs in patients with PHCC.A total of 335 consecutive patients who underwent ...

Last Updated: 31 Dec 1969

Go To URL
Benefit of neoadjuvant concurrent chemoradiotherapy for locally advanced perihilar cholangiocarcinoma.
 

Author(s): Jang Han Jung, Hyun Jik Lee, Hee Seung Lee, Jung Hyun Jo, In Rae Cho, Moon Jae Chung, Jeong Youp Park, Seung Woo Park, Si Young Song, Seungmin Bang

Journal: World J. Gastroenterol.. 2017 May;23(18):3301-3308.

 

To clarify the role of neoadjuvant concurrent chemoradiotherapy (NACCRT) followed by surgical resection for localized or locally advanced perihilar cholangiocarcinoma (CCA).

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Perihilar cholangiocarcinoma" returned 5 free, full-text review articles on human participants. First 3 results:

The clinicopathological factors associated with prognosis of patients with resectable perihilar cholangiocarcinoma: A systematic review and meta-analysis.
 

Author(s): Zengwei Tang, Yuan Yang, Zhonghong Zhao, Kongyuan Wei, Wenbo Meng, Xun Li

Journal: Medicine (Baltimore). 2018 Aug;97(34):e11999.

 

The refinement in surgical techniques combined with the preoperative management has improved the resectability rate of perihilar cholangiocarcinoma (pCCA). However, the prognosis of pCCA with curative resection is still dismal. This meta-analysis was performed to investigate the prognostic ...

Last Updated: 31 Dec 1969

Go To URL
Current Management of Perihilar Cholangiocarcinoma and Future Perspectives.
 

Author(s): Heather L Lewis, Amir A Rahnemai-Azar, Mary Dillhoff, Carl R Schmidt, Timothy M Pawlik

Journal: Chirurgia (Bucur). ;112(3):193-207.

 

Perihilar cholangiocarcinoma is the most common type of biliary tract cancer and is associated with a high mortality, usually due to late presentation. High-resolution cross-sectional imaging modalities are necessary for diagnosis and preoperative planning. Although surgical resection ...

Last Updated: 31 Dec 1969

Go To URL
Diagnostic accuracy of staging laparoscopy for detecting metastasized or locally advanced perihilar cholangiocarcinoma: a systematic review and meta-analysis.
 

Author(s): Robert J S Coelen, Anthony T Ruys, Marc G H Besselink, Olivier R C Busch, Thomas M van Gulik

Journal: Surg Endosc. 2016 10;30(10):4163-73.

 

Despite extensive preoperative staging, still almost half of patients with potentially resectable perihilar cholangiocarcinoma (PHC) have locally advanced or metastasized disease upon exploratory laparotomy. The value of routine staging laparoscopy (SL) in these patients remains unclear ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Stereotactic Body Radiation Therapy for Unresectable Perihilar Cholangiocarcinoma
 

Status: Recruiting

Condition Summary: Klatskin Tumor

 

Last Updated: 6 Dec 2017

Go to URL
Efficacy and Safety Study of PDT Using Deuteporfin for Unresectable Advanced Perihilar Cholangiocarcinoma
 

Status: Recruiting

Condition Summary: Hilar Cholangiocarcinoma

 

Last Updated: 15 Mar 2018

Go to URL
Application of Endoscopic Scissors Cutting ENBD Tube in the Treatment of Malignant Hilar Biliary Strictures
 

Status: Recruiting

Condition Summary: Endoscopic Retrograde Cholangiopancreatography; Klatskin Tumor

 

Last Updated: 30 Nov 2017

Go to URL