Hodgkin lymphoma

Common Name(s)

Hodgkin lymphoma, Hodgkin's disease

Hodgkin lymphoma is a cancer of the lymph tissue, which can be found in the lymph nodes, spleen and other organs of the immune system. There are two types of Hodgkin lymphoma, which are known as nodular and classical Hodgkin’s. The classical form is further divided into four subtypes and is characterized by the presence of what are known as "Reed–Sternberg cells" (overgrown B-cells). Although Hodgkin lymphoma starts in the bone marrow, it may also spread to other tissues of the body, depending on the stage and how aggressive the type is. Anyone can get Hodgkin lymphoma, but there are some factors that increase one’s risks. People who have or have had the Epstein-Barr virus (also known as mono or mononucleosis) or HIV are at an increased risk, as well as those with a family history of the condition. Additionally, males, young adults and the elderly, and people from the U.S., Canada, or Europe are more likely to develop Hodgkin lymphoma than women, children, or people from other geographic locations.

The most common symptom is one or more enlarged lymph node(s), but enlargement of the spleen or liver may also be a sign. Other symptoms include night sweats, unexplained weight loss, itching, back pain, and red colored patched on the skin. The most effective and commonly used method for diagnosis is a lymph node biopsy, in which the lymph node is cut open and examined. Scans such as the PET or CT scans may be used as well to determine where the cancer is or how far it has spread and the appropriate treatment options. Treatment varies depending on the individual's weight, age, and size as well as the severity of the cancer. Treatment generally involves chemotherapy, radiation, or a combination of the two. Talk to your doctor if you are experiencing any symptoms or think you have Hodgkin lymphoma.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hodgkin lymphoma" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

Last Updated: 20 Feb 2013

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The Kimberly D. Holland Hodgkins Disease Foundation

Research and Cure... One Cell At A Time. Finding a cure for Hodgkins Disease by Funding Clinical Trial Research at Memorial Sloan-Kettering Cancer Center through Fundraising efforts.

Last Updated: 15 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hodgkin lymphoma" for support, advocacy or research.

4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

View Details
Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

View Details
National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

http://www.nbmtlink.org

Last Updated: 20 Feb 2013

View Details
The Kimberly D. Holland Hodgkins Disease Foundation

Research and Cure... One Cell At A Time. Finding a cure for Hodgkins Disease by Funding Clinical Trial Research at Memorial Sloan-Kettering Cancer Center through Fundraising efforts.

http://www.hodgkinsfoundation.org

Last Updated: 15 Mar 2013

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hodgkin lymphoma" returned 1823 free, full-text research articles on human participants. First 3 results:

MicroRNA High Throughput Loss-of-Function Screening Reveals an Oncogenic Role for miR-21-5p in Hodgkin Lymphoma.
 

Author(s): Ye Yuan, Fubiao Niu, Ilja M Nolte, Jasper Koerts, Debora de Jong, Bea Rutgers, Jan Osinga, Maria Azkanaz, Martijn Terpstra, Leonid Bystrykh, Arjan Diepstra, Lydia Visser, Agnieszka Dzikiewicz-Krawczyk, Klaas Kok, Joost Kluiver, Anke van den Berg

Journal: Cell. Physiol. Biochem.. 2018 ;49(1):144-159.

 

Classical Hodgkin lymphoma (cHL) is among the most frequent lymphoma subtypes. The tumor cells originate from crippled germinal center (GC)-B cells that escaped from apoptosis. MicroRNAs (miRNAs) play important roles in B-cell maturation and aberrant expression of miRNAs contributes ...

Last Updated: 31 Dec 1969

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Safety, tolerability and pharmacokinetics of shorter duration of infusion of obinutuzumab in Japanese patients with B-cell non-Hodgkin lymphoma: final results of the phase II GATS study.
 

Author(s): Ken Ohmachi, Kiyoshi Ando, Tomohiro Kinoshita, Kyoya Kumagai, Kiyohiko Hatake, Takayuki Ishikawa, Takanori Teshima, Koji Kato, Koji Izutsu, Eisuke Ueda, Kiyohiko Nakai, Hiroshi Kuriki, Kensei Tobinai

Journal: Jpn. J. Clin. Oncol.. 2018 Aug;48(8):736-742.

 

Shorter duration of infusion of monoclonal antibody treatments may reduce treatment burden and improve healthcare resource utilization.

Last Updated: 31 Dec 1969

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[Oligoarthritis, panniculitis and pyoderma gangrenosum associated with non-Hodgkin lymphoma. Report of one case].
 

Author(s): Daniel Erlij, Carolina Cuellar, Angela Rivera, Natalia Badilla, Nicia Moldenhauer, Carolina Foster, Bernardo López, Ximena Valladares, Mary Ann Stevens

Journal: Rev Med Chil. 2018 Apr;146(4):534-537.

 

An assortment of clinical and laboratory abnormalities may occur as paraneoplastic syndromes in lymphomas. Rheumatological and dermatological manifestations such as paraneoplastic arthritis and pyoderma gangrenosum must be underscored. We report a 28 years old woman who developed ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hodgkin lymphoma" returned 176 free, full-text review articles on human participants. First 3 results:

Synchronous Hodgkin lymphoma and gastric adenocarcinoma: A rare case report and literature review.
 

Author(s): Hongying Wu, Liyan Wei, Lumei Hao, Xuemei Li, Lei Wang, Chenglu Yuan

Journal: Medicine (Baltimore). 2018 Jan;97(3):e9484.

 

Hodgkin lymphoma (HL) is a lymphoproliferative disease arising in the lymphoid tissue, which is characterized by Reed-Sternberg cells. Adenocarcinoma is the most frequent pathological type of stomach cancer. Improved survival in HL patients leads to the development of secondary malignancies. ...

Last Updated: 31 Dec 1969

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Non-Hodgkin lymphoma, diagnostic, and prognostic particularities in children - a series of case reports and a review of the literature (CARE compliant).
 

Author(s): Cristina Oana Mărginean, Lorena Elena Meliţ, Emoke Horvath, Horea Gozar, Mihaela Ioana Chinceşan

Journal: Medicine (Baltimore). 2018 Feb;97(8):e9802.

 

Non-Hodgkin lymphoma remains an unpredictable condition in pediatric patients.

Last Updated: 31 Dec 1969

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Hodgkin lymphoma involving the tonsil misdiagnosed as tonsillar carcinoma: A case report and review of the literature.
 

Author(s): You Qin, Lijuan Lu, Yanwei Lu, Kunyu Yang

Journal: Medicine (Baltimore). 2018 Feb;97(7):e9761.

 

Primary Hodgkin lymphoma (HL) involving the tonsil is extremely rare. Only about 20 such cases with verification of biopsy and immunohistochemistry have been reported. Because of its rarity and unremarkable clinical presentation, a timely correct diagnosis is very challenging.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

SHR-1210 Alone or in Combination With Decitabine in Relapsed or Refractory Hodgkin Lymphoma
 

Status: Recruiting

Condition Summary: Hodgkin Lymphoma

 

Last Updated: 28 Sep 2018

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Brazilian Prospective Hodgkin Lymphoma Registry
 

Status: Recruiting

Condition Summary: Hodgkin Lymphoma; Hodgkin Disease

 

Last Updated: 24 Oct 2017

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Last Updated: 15 Nov 2017

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