Human papillomavirus infection

Common Name(s)

Human papillomavirus infection, HPV

Human papillomavirus infection (HPV) is an infection that causes warts. There are more than 100 varieties of HPV. Different types of HPV infection can cause warts on different parts of your body. Only some types of genital HPV can cause cancer. Vaccines can help protect against the strains of genital HPV most likely to cause cervical cancer. Symptoms vary depending on the variety of HPV, but may include genital warts, common warts, plantar warts, flat warts, and cervical cancer. Some types of HPV infections occur when the virus enters your body through a cut or small tear in the outer layer of your skin. It is primarily transferred by skin-to skin contact.

Genital HPV infections are contracted through vaginal, anal, oral sex and other skin-to-skin contact in the genital region. Risk factors of HPV infection include weakened immune system, damaged skin, and personal contact. Serious complications of HPV infection are oral and upper respiratory lesions and cervical, genital, anus, mouth and upper respiratory tract cancer. Depending on the variety of HPV infection, your doctor may be able to diagnose with a visual inspection of any warts or lesions. If genital warts aren’t visible, a vinegar (acetic acid) solution test, Pap test, and DNA test may be used to diagnose HPV.

It is important to try to prevent HPV types that causes genital warts. You may be able to reduce your risk of developing genital warts by using a latex condom; this will prevent some but not all HPV transmission. The HPV vaccines are also important to prevent HPV infections that are most likely to cause cervical cancer. The Centers for Disease Control and Prevention (CDC) recommends routine HPV vaccination for girls and boys ages 11 and 12. If you or someone you know has been diagnosed with an HPV infection, talk to your doctor about the most current prevention and treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Human papillomavirus infection" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 9 Jul 2015

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

Last Updated: 11 Jul 2016

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Human papillomavirus infection" for support, advocacy or research.

HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 9 Jul 2015

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

http://www.thestdproject.com/

Last Updated: 11 Jul 2016

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Human papillomavirus infection" returned 730 free, full-text research articles on human participants. First 3 results:

Detection and genotyping of human papillomavirus (HPV) in HIV-infected women and its relationship with HPV/HIV co-infection.
 

Author(s): Rodolfo Miglioli Badial, Marina Carrara Dias, Bruna Stuqui, Patrícia Pereira Dos Santos Melli, Silvana Maria Quintana, Caroline Measso do Bonfim, José Antônio Cordeiro, Tatiana Rabachini, Marilia de Freitas Calmon, Paola Jocelan Scarin Provazzi, Paula Rahal

Journal: Medicine (Baltimore). 2018 Apr;97(14):e9545.

 

HPV have been identified as high-risk and low-risk, depending on their association with the development of cancer. HPV infections can be facilitated by co-infection with HIV. Here, we investigated HPV prevalence and genotypes and the risk factors affecting HPV/HIV co-infection. Forty ...

Last Updated: 31 Dec 1969

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T cell receptor repertoire among women who cleared and failed to clear cervical human papillomavirus infection: An exploratory proof-of-principle study.
 

Author(s): Krystle A Lang Kuhs, Shih-Wen Lin, Xing Hua, Mark Schiffman, Robert D Burk, Ana Cecilia Rodriguez, Rolando Herrero, Christian C Abnet, Neal D Freedman, Ligia A Pinto, David Hamm, Harlan Robins, Allan Hildesheim, Jianxin Shi, Mahboobeh Safaeian

Journal:

 

It is unknown why a minority of women fail to clear human papillomavirus (HPV) and develop precancer/cancer. Differences in T-cell receptor (TCR) repertoires may identify HPV16-infected women at highest-risk for progression to cancer. We conducted a proof-of-principle study nested ...

Last Updated: 31 Dec 1969

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Co-infection of sexually transmitted pathogens and Human Papillomavirus in cervical samples of women of Brazil.
 

Author(s): Aline Teixeira Amorim, Lucas Miranda Marques, Guilherme Barreto Campos, Tássia Neves Lobão, Vanesca de Souza Lino, Ricardo Cesar Cintra, Maria Antonieta Andreoli, Luisa Lina Villa, Enrique Boccardo, Antonio Carlos Ricardo Braga Junior, Rossana Verónica Mendoza López, Djanilson Barbosa Dos Santos, Gerson Maciel de Souza, Carla Cristina Romano, Jorge Timenetsky

Journal:

 

Some sexually transmitted infectious agents, such as Chlamydia trachomatis and Herpes simplex, cause local inflammation, and could contribute to Human Papillomavirus (HPV) and cervical lesion progression. Thus, the aim of this study was to determine any association between the presence ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Human papillomavirus infection" returned 65 free, full-text review articles on human participants. First 3 results:

Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression.
 

Author(s): Cody J Warren, Joseph A Westrich, Koenraad Van Doorslaer, Dohun Pyeon

Journal:

 

The apolipoprotein B messenger RNA-editing, enzyme-catalytic, polypeptide-like 3 (APOBEC3) family of cytidine deaminases plays an important role in the innate immune response to viral infections by editing viral genomes. However, the cytidine deaminase activity of APOBEC3 enzymes ...

Last Updated: 31 Dec 1969

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Targeting Persistent Human Papillomavirus Infection.
 

Author(s): Srinidhi Shanmugasundaram, Jianxin You

Journal:

 

While the majority of Human papillomavirus (HPV) infections are transient and cleared within a couple of years following exposure, 10-20% of infections persist latently, leading to disease progression and, ultimately, various forms of invasive cancer. Despite the clinical efficiency ...

Last Updated: 31 Dec 1969

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Human papillomavirus infection as a prognostic marker for lung adenocarcinoma: a systematic review and meta-analysis.
 

Author(s): Lanwei Guo, Shuzheng Liu, Shaokai Zhang, Qiong Chen, Meng Zhang, Peiliang Quan, Xibin Sun

Journal: Oncotarget. 2017 May;8(21):34507-34515.

 

Although a number of studies have investigated the association between human papillomavirus (HPV) and lung cancer prognosis, the results remain inconsistent. We therefore conducted a meta-analysis of epidemiologic studies to address this issue. Searches of the MEDLINE and EMBASE electronic ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Lubricant Investigation in Men to Inhibit Transmission of HPV Infection
 

Status: Recruiting

Condition Summary: Human Papillomavirus Infection

 

Last Updated: 28 Aug 2017

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Last Updated: 18 Apr 2018

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Transmission Reduction and Prevention With HPV Vaccination (TRAP-HPV) Study
 

Status: Recruiting

Condition Summary: Human Papillomavirus Infection

 

Last Updated: 28 Aug 2017

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