Huntington disease
Common Name(s)
Huntington disease, Huntington's chorea
Advocacy and Support Organizations
Condition Specific Organizations
Following organizations serve the condition "Huntington disease" for support, advocacy or research.
Caring Voice Coalition empowers patients who live with a life threatening chronic disease through comprehensive outreach programs and services aimed at financial, emotional and educational support. With a steadfast dedication to the organization’s set of core values, our knowledgeable, caring staff maintains our solid reputation as a dependable, responsive organization with a unique, holistic approach to improving the lives of our patients.
The Hereditary Disease Foundation is a non-profit, basic-science organization dedicated to the cure of genetic disease, with a focus on Huntington disease.
We are a national non-profit voluntary health agency dedicated to finding a cure for Huntington's Disease. We provide vital support, information and educational services to improve the lives of those affected by HD, offer resources and guidance for HD families through our national network of volunteer-based chapters and affiliates as well as through our HDSA Centers of Excellence for Family Services, and promote and support research to find a cure for HD.
The Movement Disorder Society (MDS) is an international professional society of clinicians, scientists, and other healthcare professionals, who are interested in Parkinson's disease, related neurodegenerative and neurodevelopmental disorders, hyperkinetic movement disorders, and abnormalities in muscle tone and motor control.
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Advocacy and Support Organizations
Condition Specific Organizations
Following organizations serve the condition "Huntington disease" for support, advocacy or research.
Caring Voice Coalition empowers patients who live with a life threatening chronic disease through comprehensive outreach programs and services aimed at financial, emotional and educational support. With a steadfast dedication to the organization’s set of core values, our knowledgeable, caring staff maintains our solid reputation as a dependable, responsive organization with a unique, holistic approach to improving the lives of our patients.
http://www.caringvoice.org The Hereditary Disease Foundation is a non-profit, basic-science organization dedicated to the cure of genetic disease, with a focus on Huntington disease.
http://www.hdfoundation.org We are a national non-profit voluntary health agency dedicated to finding a cure for Huntington's Disease. We provide vital support, information and educational services to improve the lives of those affected by HD, offer resources and guidance for HD families through our national network of volunteer-based chapters and affiliates as well as through our HDSA Centers of Excellence for Family Services, and promote and support research to find a cure for HD.
http://www.hdsa.org The Movement Disorder Society (MDS) is an international professional society of clinicians, scientists, and other healthcare professionals, who are interested in Parkinson's disease, related neurodegenerative and neurodevelopmental disorders, hyperkinetic movement disorders, and abnormalities in muscle tone and motor control.
http://www.movementdisorders.org/MDS.htmRecommended Apps
Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.
Finding the right clinical trial for Huntington disease can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.
Scientific Literature
Articles from the PubMed Database
Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Huntington disease" returned 396 free, full-text research articles on human participants.
First 3 results:
Journal: Proc. Natl. Acad. Sci. U.S.A.. 2018 09;115(37):E8765-E8774.
Huntington disease (HD) is an autosomal dominant neurodegenerative disorder caused by expanded CAG repeats in the gene (). Although mutant HTT is expressed during embryonic development and throughout life, clinical HD usually manifests later in adulthood. A number of studies document ...
Journal:
Huntington disease (HD) is caused by the expression of mutant huntingtin (mHTT) bearing a polyglutamine expansion. In HD, mHTT accumulation is accompanied by a dysfunction in basal autophagy, which manifests as specific defects in cargo loading during selective autophagy. Here we ...
Journal:
Mitochondrial dysfunction may represent a pathogenic factor in Huntington disease (HD). Physical exercise leads to enhanced mitochondrial function in healthy participants. However, data on effects of physical exercise on HD skeletal muscle remains scarce. We aimed at investigating ...
To view other free, full-text articles on human participants, please click on the link below.
Reviews from the PubMed Database
Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Huntington disease" returned 33 free, full-text review articles on human participants.
First 3 results:
Journal:
Huntington disease (HD) is an incurable neurodegenerative disorder caused by a dominant mutation on the 4th chromosome. We aim to present a scientometric analysis of the extant scientific undertakings devoted to better understanding HD. Therefore, a quantitative study was performed ...
Journal: Handb Clin Neurol. 2017 ;144():107-111.
Preimplantation genetic diagnosis (PGD) is a form of prenatal diagnosis applied to potential parents with known carrier status of a genetic disease, such as Huntington disease. It employs the use of polymerase chain reaction to amplify single cells from early embryos obtained with ...
Journal: Neurosci Bull. 2017 Jun;33(3):312-316.
Huntington disease (HD) is a progressive autosomal dominantly inherited neurodegenerative disorder, characterized with the typical manifestations of involuntary movements, cognitive dysfunction, and psychiatric or behavioral disturbance. It results from an expansion in the number ...
To view other free, full-text review articles on human participants, please click on the link below.
Symptoms, Diagnosis, and Treatment
https://ghr.nlm.nih.gov/condition/huntington-disease-like-syndrome
https://ghr.nlm.nih.gov/gene/HTT
https://ghr.nlm.nih.gov/gene/HIP1
https://ghr.nlm.nih.gov/gene/KALRN
https://ghr.nlm.nih.gov/gene/PFN1
https://ghr.nlm.nih.gov/gene/TBP
https://ghr.nlm.nih.gov/gene/SETD2
https://ghr.nlm.nih.gov/gene/TSPAN7
https://ghr.nlm.nih.gov/gene/JPH3
https://ghr.nlm.nih.gov/primer/evolution
https://ghr.nlm.nih.gov/gene/CASP8
https://ghr.nlm.nih.gov/gene/PRNP
https://ghr.nlm.nih.gov/primer/anticipation
https://ghr.nlm.nih.gov/condition/danon-disease
https://ghr.nlm.nih.gov/condition/dent-disease
https://ghr.nlm.nih.gov/condition/darier-disease
https://ghr.nlm.nih.gov/condition/cln4-disease
https://ghr.nlm.nih.gov/condition/celiac-disease
https://ghr.nlm.nih.gov/condition/cln6-disease
Clinical Trial Information This information is provided by ClinicalTrials.gov
Condition Summary: Huntington's Disease
Condition Summary: Huntington Disease
Finding the right clinical trial for Huntington disease can be challenging. However, with TrialsFinder (which uses the Reg4ALL database and privacy controls by Private Access), you can permit researchers to let you know opportunities to consider - all without revealing your identity.