Hydrocephalus

Common Name(s)

Hydrocephalus

Hydrocephalus is a condition characterized by excessive accumulation of fluid in the brain. Although it was once known as "water on the brain," the "water" is actually cerebrospinal fluid (CSF) - clear fluid that surrounds the brain and spinal cord. Excess CSF builds up when it cannot drain from the brain due to a blockage in a passage through which the fluid normally flows.  This excess fluid causes an abnormal widening of spaces in the brain called ventricles; this can create harmful pressure on brain tissue. Symptoms vary with age, disease progression, and individual differences in tolerance to the condition. Hydrocephalus may be congenital (present at birth) or acquired. The causes are not fully understood; it may result from inherited genetic abnormalities or developmental disorders; complications of premature birth; diseases such as meningitis; tumors; traumatic head injury; or other causes. It is most often treated by surgically inserting a shunt system.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hydrocephalus" for support, advocacy or research.

Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

Last Updated: 18 Mar 2013

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Hydrocephalus Association

The Hydrocephalus Association’s goal is to eliminate the challenges of hydrocephalus by stimulating innovative research and providing support, education and advocacy for individuals, families and professionals dealing with the complex issues of the condition.

Last Updated: 19 Nov 2012

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Missouri Family to Family

Missouri Family to Family provides customized information that allows families and individuals about needed resources and supports, navigating the maze of systems and services, as well as options to make their vision for their life possible. MOF2F also offers Sharing Our Strengths, which connects individuals with disabilities and/or their caregivers to a person who is available to listen with an open heart and open mind, offering emotional support, practical information, and/or shared experiences.

Last Updated: 15 Apr 2014

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Pediatric Brain Foundation

Pediatric Brain Foundation's Mission is Three-fold: 1. Expedite scientific research to find treatments and cures for ALL of the more than 14 million children, in the U.S. alone, living with some form of neurological disorder 2. Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology 3. Educate the public and public officials on the critical importance of funding pediatric neurological research

Last Updated: 22 Apr 2015

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Spina Bifida Resource

Spina Bifida Resource's mission is to promote the prevention of spina bifida and its secondary conditions and to enhance the health and well-being of those affected.

Last Updated: 15 Nov 2012

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hydrocephalus" for support, advocacy or research.

Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

http://www.CSFinfo.org

Last Updated: 18 Mar 2013

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Hydrocephalus Association

The Hydrocephalus Association’s goal is to eliminate the challenges of hydrocephalus by stimulating innovative research and providing support, education and advocacy for individuals, families and professionals dealing with the complex issues of the condition.

http://www.hydroassoc.org

Last Updated: 19 Nov 2012

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Missouri Family to Family

Missouri Family to Family provides customized information that allows families and individuals about needed resources and supports, navigating the maze of systems and services, as well as options to make their vision for their life possible. MOF2F also offers Sharing Our Strengths, which connects individuals with disabilities and/or their caregivers to a person who is available to listen with an open heart and open mind, offering emotional support, practical information, and/or shared experiences.

http://www.mofamilytofamily.org

Last Updated: 15 Apr 2014

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Pediatric Brain Foundation

Pediatric Brain Foundation's Mission is Three-fold: 1. Expedite scientific research to find treatments and cures for ALL of the more than 14 million children, in the U.S. alone, living with some form of neurological disorder 2. Provide families and health care professionals with up-to-date information and resources on the latest discoveries in pediatric neurology 3. Educate the public and public officials on the critical importance of funding pediatric neurological research

http://www.pediatricbrainfoundation.org

Last Updated: 22 Apr 2015

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Spina Bifida Resource

Spina Bifida Resource's mission is to promote the prevention of spina bifida and its secondary conditions and to enhance the health and well-being of those affected.

http://spinabifidaresource.weebly.com/

Last Updated: 15 Nov 2012

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hydrocephalus" returned 883 free, full-text research articles on human participants. First 3 results:

Gait in normal pressure hydrocephalus: characteristics and effects of the CSF tap test.
 

Author(s): Ricardo Krause Martinez de Souza, Samanta Fabrício Blattes da Rocha, Rodrigo Tomazini Martins, Pedro André Kowacs, Ricardo Ramina

Journal: Arq Neuropsiquiatr. 2018 May;76(5):324-331.

 

Normal pressure hydrocephalus (NPH), described by Hakim and Adams in 1965, is characterized by gait apraxia, urinary incontinence, and dementia. It is associated with normal cerebrospinal fluid (CSF) pressure and ventricular dilation that cannot be attributed to cerebral atrophy.

Last Updated: 31 Dec 1969

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Normal pressure hydrocephalus and the predictive value of presurgical tests.
 

Author(s): Benito P Damasceno

Journal: Arq Neuropsiquiatr. 2018 05;76(5):285-286.

 

Last Updated: 31 Dec 1969

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FSI simulation of CSF hydrodynamic changes in a large population of non-communicating hydrocephalus patients during treatment process with regard to their clinical symptoms.
 

Author(s): Seifollah Gholampour

Journal:

 

3D fluid-structure interaction modelling was utilized for simulation of 13 normal subjects, 11 non-communicating hydrocephalus (NCH) patients at pre-treatment phase, and 3 patients at five post-treatment phases. Evaluation of ventricles volume and maximum CSF pressure (before shunting) ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hydrocephalus" returned 69 free, full-text review articles on human participants. First 3 results:

Opportunities in posthemorrhagic hydrocephalus research: outcomes of the Hydrocephalus Association Posthemorrhagic Hydrocephalus Workshop.
 

Author(s): Jenna E Koschnitzky, Richard F Keep, David D Limbrick, James P McAllister, Jill A Morris, Jennifer Strahle, Yun C Yung

Journal:

 

The Hydrocephalus Association Posthemorrhagic Hydrocephalus Workshop was held on July 25 and 26, 2016 at the National Institutes of Health. The workshop brought together a diverse group of researchers including pediatric neurosurgeons, neurologists, and neuropsychologists with scientists ...

Last Updated: 31 Dec 1969

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Ventriculoperitoneal shunt insertion for hydrocephalus in human immunodeficiency virus-infected adults: a systematic review and meta-analysis protocol.
 

Author(s): James J M Loan, Ncedile Mankahla, Graeme Meintjes, A Graham Fieggen

Journal:

 

Hydrocephalus is a recognised complication of human immunodeficiency virus (HIV)-related opportunistic infections. Symptomatic raised cerebrospinal fluid pressure can be treated with ventriculoperitoneal shunt insertion (VPS). In HIV-infected patients however, there is a concern that ...

Last Updated: 31 Dec 1969

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Blood-brain barrier and foetal-onset hydrocephalus, with a view on potential novel treatments beyond managing CSF flow.
 

Author(s): M Guerra, J L Blázquez, E M Rodríguez

Journal:

 

Despite decades of research, no compelling non-surgical therapies have been developed for foetal hydrocephalus. So far, most efforts have pointed to repairing disturbances in the cerebrospinal fluid (CSF) flow and to avoid further brain damage. There are no reports trying to prevent ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Improving Infant Hydrocephalus Outcomes in Uganda
 

Status: Not yet recruiting

Condition Summary: Hydrocephalus

 

Last Updated: 27 Aug 2018

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Study of Choroid Plexus Cauderization in Patients With Hydrocephalus
 

Status: Recruiting

Condition Summary: Hydrocephalus

 

Last Updated: 12 Feb 2018

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Endoscopic Third Ventriculostomy Versus Ventriculo-peritoneal Shunting in Idiopathic Normal Pressure Hydrocephalus
 

Status: Recruiting

Condition Summary: Normal Pressure Hydrocephalus

 

Last Updated: 7 Aug 2017

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