Hyperemesis gravidarum

Common Name(s)

Hyperemesis gravidarum

Hyperemesis gravidarum is severe nausea and vomiting that starts during the first trimester or first 12 weeks of pregnancy. Symptoms usually begin 4 to 6 weeks into the pregnancy. Symptoms may lessen by 15 to 20 weeks, although for some women the symptoms may last the entire pregnancy. Risk factors for this condition are a diet high in saturated fat, epilepsy, untreated asthma, kidney or liver disease, and a history of hyperemesis gravidarum in your family. Hyperemesis gravidarum is more common in the first pregnancy and when carrying more than one baby at a time.

In addition to nausea and vomiting, hyperemesis gravidarum may cause dehydration, significant weight loss, nutritional deficiencies, electrolyte imbalance, anemia, fatigue, and headaches. If you or someone you know is experiencing severe nausea and vomiting and may be pregnant, it is important to talk to your doctor or obstetrician. Early treatment is important because dehydration and weight loss during pregnancy are dangerous for both you and your baby.

Testing for this condition may include a blood draw to check blood count and electrolyte levels, urine sample, physical examination, and ultrasound imaging. Treatment usually includes rest, fluids, and nutritional supplements as well as emotional support. If you have been diagnosed with hyperemesis gravidarum, talk to your doctor or obstetrician about the most current treatment options. Support groups are also available for more resources and information.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hyperemesis gravidarum" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hyperemesis gravidarum" returned 84 free, full-text research articles on human participants. First 3 results:

Hyperemesis gravidarum and placental dysfunction disorders.
 

Author(s): Heleen M Koudijs, Ary I Savitri, Joyce L Browne, Dwirani Amelia, Mohammad Baharuddin, Diederick E Grobbee, Cuno S P M Uiterwaal

Journal:

 

Evidence about the consequence of hyperemesis gravidarum (HG) on pregnancy outcomes is still inconclusive. In this study, we evaluated if occurrence of hyperemesis gravidarum is associated with placental dysfunction disorders and neonatal outcomes.

Last Updated: 31 Dec 1969

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Wernicke's encephalopathy due to hyperemesis gravidarum: Clinical and magnetic resonance imaging characteristics.
 

Author(s): V V Ashraf, J Prijesh, R Praveenkumar, K Saifudheen

Journal: J Postgrad Med. ;62(4):260-263.

 

Hyperemesis gravidarum-induced Wernicke's encephalopathy (WE) is an underestimated condition. The purpose of this study is to improve its awareness and early diagnosis. We report five cases of WE secondary to hyperemesis gravidarum. Classic triad of encephalopathy, ataxia, and ocular ...

Last Updated: 31 Dec 1969

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Relationship between hyperemesis gravidarum and small-for-gestational-age in the Japanese population: the Japan Environment and Children's Study (JECS).
 

Author(s): Seiichi Morokuma, Mototsugu Shimokawa, Kiyoko Kato, Masafumi Sanefuji, Eiji Shibata, Mayumi Tsuji, Ayako Senju, Toshihiro Kawamoto, Koichi Kusuhara,

Journal:

 

Small-for-gestational-age in infancy is a known risk factor not only for short-term prognosis but also for several long-term outcomes, such as neurological and metabolic disorders in adulthood. Previous research has shown that severe nausea and vomiting in early pregnancy (NVP) and ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hyperemesis gravidarum" returned 8 free, full-text review articles on human participants. First 3 results:

Consequences of hyperemesis gravidarum for offspring: a systematic review and meta-analysis.
 

Author(s): M V E Veenendaal, A F M van Abeelen, R C Painter, J A M van der Post, T J Roseboom

Journal: BJOG. 2011 Oct;118(11):1302-13.

 

There is evidence that hyperemesis gravidarum (HG) is associated with a predominance of female fetuses, lower birthweights and shorter gestational ages at birth. As the adverse effects of prematurity and low birthweight on disease risk in later life have become increasingly clear, ...

Last Updated: 31 Dec 1969

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Managing hyperemesis gravidarum: a multimodal challenge.
 

Author(s): J K Jueckstock, R Kaestner, I Mylonas

Journal:

 

Up to 90% of pregnant women experience nausea and vomiting. When prolonged or severe, this is known as hyperemesis gravidarum (HG), which can, in individual cases, be life threatening. In this article the aetiology, diagnosis and treatment strategies will be presented based on a selective ...

Last Updated: 31 Dec 1969

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Hyperemesis gravidarum: a review.
 

Author(s): S Sonkusare

Journal: Med. J. Malaysia. 2008 Aug;63(3):272-6; quiz 277.

 

Vomiting in pregnancy is a very common phenomenon, though not well understood. The extreme form, hyperemesis gravidarum can lead to severe complications. Articles published in the last decade in this field were searched and studied. Various aetiological factors were identified, the ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Bone Health in Hyperemesis Gravidarum
 

Status: Recruiting

Condition Summary: Hyperemesis Gravidarum

 

Last Updated: 7 Aug 2016

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Comparison of Gabapentin and Metoclopramide for Treating Hyperemesis Gravidarum
 

Status: Recruiting

Condition Summary: Hyperemesis Gravidarum

 

Last Updated: 2 Aug 2015

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Endothelial Dysfunction in Hyperemesis Gravidarum
 

Status: Recruiting

Condition Summary: Hyperemesis; Gravidarum, With Dehydration

 

Last Updated: 8 Dec 2016

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