Infectious arthritis

Common Name(s)

Infectious arthritis

Infectious arthritis is a painful swelling in the joints caused by a bacterial, viral, or fungal infection. Infectious arthritis usually results from infectious organisms in the bloodstream travelling to and infecting a joint. Organisms can also enter the body through open wounds to reach a joint. Fungal infections develop more slowly and are typically less severe than bacterial infections.

Risk factors for infectious arthritis include having underlying health conditions that weaken the immune system, such as cancer, diabetes, and HIV/AIDS, or having joint damage. The elderly and very young are also at increased risk. Symptoms of infectious arthritis include severe pain in the affected joint or joints, fever, chills, impaired mobility, joint swelling, fatigue, and redness or warmth of the joint. Most often, only one joint is affected. The knee is the joint most frequently affected by infectious arthritis.

Infectious arthritis is diagnosed by taking a sample of the joint fluid. This fluid will often have a high white blood cell count, as these are the cells responsible for fighting the infectious agent. Bacteria and other organisms can be grown and identified from this fluid. Treatment of infectious arthritis usually involves a combination of antibiotics, antivirals, or antifungals, and draining of the joint fluid. Infected tissue may also need to be removed in a procedure called an arthroscopy. If you have been diagnosed with infectious arthritis, talk to your doctor about the most current treatment options. Support groups are available for more resources and information.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Infectious arthritis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Infectious arthritis" returned 31 free, full-text research articles on human participants. First 3 results:

Use of a baseline risk score to identify the risk of serious infectious events in patients with rheumatoid arthritis during certolizumab pegol treatment.
 

Author(s): Jeffrey R Curtis, Kevin Winthrop, Cathy O'Brien, Matladi N Ndlovu, Marc de Longueville, Boulos Haraoui

Journal:

 

The risk of serious infectious events (SIEs) is increased in patients with rheumatoid arthritis (RA). The aim of this study was to develop an age-adjusted comorbidity index (AACI) to predict, using baseline characteristics, the SIE risk in patients with RA treated with certolizumab pegol (CZP).

Last Updated: 31 Dec 1969

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Dose relationship between oral glucocorticoids and tumor necrosis factor inhibitors and the risk of hospitalized infectious events among patients with rheumatoid arthritis.
 

Author(s): Jennifer Schenfeld, Jan Iles, Mona Trivedi, Neil A Accortt

Journal: Rheumatol. Int.. 2017 Jul;37(7):1075-1082.

 

The objective of this study was to evaluate the impact of oral glucocorticoid (GC) dose on rates of hospitalized infectious events (HIEs) among RA patients newly exposed to tumor necrosis factor inhibitor (TNFi) therapy. This retrospective cohort study used data from the MarketScan ...

Last Updated: 31 Dec 1969

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Rheumatoid arthritis triple therapy compared with etanercept: difference in infectious and gastrointestinal adverse events.
 

Author(s): Lien T Quach, Bei-Hung Chang, Mary T Brophy, Soe Soe Thwin, Keri Hannagan, James R O'Dell

Journal: Rheumatology (Oxford). 2017 03;56(3):378-383.

 

The main aim of this study was to examine the differences between triple therapy (T: SSZ and HCQ added to MTX) and etanercept (E) added to MTX with regard to the infectious and gastrointestinal (GI) adverse events (AEs) reported in The Rheumatoid Arthritis Comparison of Active Therapies Trial.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Infectious arthritis" returned 5 free, full-text review articles on human participants. First 3 results:

When a patient suspected with juvenile idiopathic arthritis turns out to be diagnosed with an infectious disease - a review of Lyme arthritis in children.
 

Author(s): Krzysztof Orczyk, Joanna Świdrowska-Jaros, Elżbieta Smolewska

Journal:

 

The Lyme arthritis is a common manifestation of infection with Borrelia burgdorferi spirochete. Despite its infectious background, the inflammation clinically and histopatologically resembles juvenile idiopathic arthritis. As it affects a considerable number of Lyme disease patients, ...

Last Updated: 31 Dec 1969

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Nanomedicines for chronic non-infectious arthritis: the clinician's perspective.
 

Author(s): Israel Rubinstein, Guy L Weinberg

Journal: Nanomedicine. 2012 Sep;8 Suppl 1():S77-82.

 

Rheumatoid arthritis (RA) and osteoarthritis (OA) are prevalent chronic health conditions. However, despite recent advances in medical therapeutics, their treatment still represents an unmet medical need because of safety and efficacy concerns with currently prescribed drugs. Accordingly, ...

Last Updated: 31 Dec 1969

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[TNFalpha blockers and infectious risk in rheumatoid arthritis].
 

Author(s): B Raffeiner, C Botsios, F Ometto, L Bernardi, A Montante, P Sfriso, S Todesco, L Punzi

Journal: Reumatismo. ;61(3):165-73.

 

Patients suffering from rheumatoid arthritis have increased risk of infections when compared with general population. The risk depends directly from disease activity and severity. Furthermore, risk increases with aging, immunosuppressive agents and comorbidities such as diabetes, ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Short 3-week Antibiotic Treatment Versus 6 Weeks in Adults With Septic Arthritis of Native Joint
 

Status: Not yet recruiting

Condition Summary: Septic Arthritis

 

Last Updated: 22 Oct 2018

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Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis
 

Status: Recruiting

Condition Summary: Joint Infection; Infection of Hip Joint (Disorder); Infection of Shoulder Joint; Septic Arthritis

 

Last Updated: 9 Oct 2018

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Dalbavancin For The Treatment of Gram Positive Osteoarticular Infections
 

Status: Recruiting

Condition Summary: Bone Infection; Osteomyelitis; Septic Arthritis; Joint Infection; Prosthetic Joint Infection

 

Last Updated: 2 Feb 2018

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