Infective endocarditis

Common Name(s)

Infective endocarditis

Infective endocarditis is an infection of the heart lining, heart valves, or blood vessels. The infection is usually caused by bacteria (bacterial endocarditis) but in some rare cases can be caused by fungus (fungal endocarditis). The risk of endocarditis is greater in individuals with heart conditions that prevent blood from moving correctly through the heart, such as those with congenital heart defects, damaged heart valves, or an implanted heart device. Those who have HIV/AIDS or IV drug users are also at increased risk for developing infective endocarditis.

Symptoms of infective endocarditis include fever, chills, fatigue, and achiness. Later symptoms include coughing, shortness of breath, weight loss, muscle and joint pain, a heart murmur, and small spots of blood under the skin or fingernails. The symptoms of infective endocarditis will typically become more severe over time as the bacteria or fungi continues to grow. It is important to seek treatment if you experience these symptoms. If untreated, endocarditis can be fatal.

Infective endocarditis can often be diagnosed using a physical examination, an ultrasound of the heart (echocardiogram), testing of heart rhythm with an EKG, blood cultures to test for bacteria, and an X-ray of the chest. Treatment usually includes IV antibiotics. Good dental hygiene is an important preventative measure, as bacteria from the mouth are likely to enter the bloodstream and can then grow in the heart. Check with your doctor if you think you may be at risk for endocarditis, and you may be given antibiotics to take before a dental procedure. If you have been diagnosed with infective endocarditis, talk to your doctor about the most current treatment options.

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Condition Specific Organizations

Following organizations serve the condition "Infective endocarditis" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Infective endocarditis" returned 983 free, full-text research articles on human participants. First 3 results:

Infective Endocarditis Associated with Atopic Dermatitis.
 

Author(s): Shigeaki Aoyagi, Takeshi Oda, Kumiko Wada, Eiji Nakamura, Tomokazu Kosuga, Hiroshi Yasunaga

Journal: Int Heart J. 2018 Mar;59(2):420-423.

 

We report a case of aortic valve infective endocarditis (IE) in a 24-year-old man with atopic dermatitis (AD). He had a history of balloon valvuloplasty for a stenotic bicuspid aortic valve, and had dental caries but no invasive dental procedure before the onset of IE. On admission, ...

Last Updated: 31 Dec 1969

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Outcome and prognostic factors of patients with right-sided infective endocarditis requiring intensive care unit admission.
 

Author(s): Hugues Georges, Olivier Leroy, Norair Airapetian, Nicolas Lamblin, Elie Zogheib, Patrick Devos, Sebastien Preau,

Journal:

 

Right-sided infective endocarditis (RSIE) is an uncommon diagnosis accounting for less than 10% of cases of infective endocarditis. Optimal management for severely ill patients with RSIE remains challenging because few studies reported on management and outcome. The goal of our study ...

Last Updated: 31 Dec 1969

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Outcome of Enterococcus faecalis infective endocarditis according to the length of antibiotic therapy: Preliminary data from a cohort of 78 patients.
 

Author(s): Juan M Pericàs, Carlos Cervera, Asunción Moreno, Cristina Garcia-de-la-Mària, Manel Almela, Carles Falces, Eduard Quintana, Bàrbara Vidal, Jaume Llopis, David Fuster, Carlos A Mestres, Francesc Marco, Jose M Miró,

Journal:

 

International guidelines recommend 4 weeks of treatment with ampicillin plus gentamicin (A+G) for uncomplicated native valve Enterococcus faecalis infective endocarditis (EFIE) and 6 weeks in the remaining cases. Ampicillin plus ceftriaxone (A+C) is always recommended for at least ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Infective endocarditis" returned 114 free, full-text review articles on human participants. First 3 results:

Probiotics and infective endocarditis in patients with hereditary hemorrhagic telangiectasia: a clinical case and a review of the literature.
 

Author(s): Evangelo Boumis, Alessandro Capone, Vincenzo Galati, Carolina Venditti, Nicola Petrosillo

Journal:

 

In the last decades, probiotics have been widely used as food supplements because of their putative beneficial health effects. They are generally considered safe but rare reports of serious infections caused by bacteria included in the definition of probiotics raise concerns on their ...

Last Updated: 31 Dec 1969

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A chronic hemodialysis patient with isolated pulmonary valve infective endocarditis caused by non-albicans Candida: a rare case and literature review.
 

Author(s): Chih-Hao Chang, Myo-Ming Huang, Dong-Feng Yeih, Kuo-Cheng Lu, Yi-Chou Hou

Journal:

 

Isolated pulmonary valve infective endocarditis caused by Candida is rare in chronic hemodialysis patients. The 2009 Infectious Diseases Society of America guidelines suggest the combined use of surgery and antibiotics to treat candidiasis; however, successful nonsurgical treatment ...

Last Updated: 31 Dec 1969

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Laboratory Diagnosis of Infective Endocarditis.
 

Author(s): Rachael M Liesman, Bobbi S Pritt, Joseph J Maleszewski, Robin Patel

Journal: J. Clin. Microbiol.. 2017 Sep;55(9):2599-2608.

 

Infective endocarditis is life-threatening; identification of the underlying etiology informs optimized individual patient management. Changing epidemiology, advances in blood culture techniques, and new diagnostics guide the application of laboratory testing for diagnosis of endocarditis. ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 13 Mar 2018

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Clinical Metagenomics of Infective Endocarditis
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 22 Jun 2017

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Infective Endocarditis in the Elderly
 

Status: Recruiting

Condition Summary: Infective Endocarditis

 

Last Updated: 21 Sep 2016

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