Inflammatory bowel disease

Common Name(s)

Inflammatory bowel disease, IBD

Inflammatory bowel disease (IBD) is the chronic redness and swelling (inflammation) of all or part of the digestive tract, which includes the esophagus, stomach, small intestine, and large intestine. The exact cause of the inflammation in IBD is not known, but a person’s immune system and genetic makeup are both thought to play a role. Risk factors for developing IBD includes older age, Caucasian (white) ethnic background, cigarette smoking, and using certain medications.

The two main types of IBD are ulcerative colitis and Crohn’s disease. Ulcerative colitis is a condition that causes inflammation and sores (ulcers) on the inside lining of the large intestine. Crohn’s disease causes inflammation that spreads deep into the affected tissue and usually affects the large intestine, the small intestine, or both. Symptoms of IBD vary and depend on the location and severity of the inflammation. Symptoms may include diarrhea, fever and fatigue, abdominal pain and cramping, blood in the stool, reduced appetite, and unintended weight loss.

To diagnose IBD, a physician will first rule out other possible causes of the symptoms. To confirm a diagnosis of IBD, your doctor may order a blood test to look for low red blood cells (anemia), a procedure that uses a small camera to examines your digestive tract for signs of IBD (endoscopy or colonoscopy), and imaging tests (X-rays, CT, or MRI) to look for evidence of IBD. Treatment includes the use of medications that reduces the immune system’s response and decreases the inflammation in the digestive tract. In severe cases, surgery may be needed. Although this condition is serious, affected individuals can live a normal life with proper treatment and care. If you or your child has been diagnosed with IBD, talk with your doctor about the current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Inflammatory bowel disease" for support, advocacy or research.

Crohn's & Colitis Foundation of America, Inc.

CCFA's mission is to cure Crohn's disease and ulcerative colitis and to improve the quality of life of children and adults affected by these diseases.

Last Updated: 8 Apr 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Inflammatory bowel disease" for support, advocacy or research.

Crohn's & Colitis Foundation of America, Inc.

CCFA's mission is to cure Crohn's disease and ulcerative colitis and to improve the quality of life of children and adults affected by these diseases.

http://www.ccfa.org

Last Updated: 8 Apr 2014

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Inflammatory bowel disease" returned 2502 free, full-text research articles on human participants. First 3 results:

Health-Risk Behaviors and Chronic Conditions Among Adults with Inflammatory Bowel Disease - United States, 2015 and 2016.
 

Author(s): Fang Xu, James M Dahlhamer, Emily P Zammitti, Anne G Wheaton, Janet B Croft

Journal:

 

Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, involves chronic inflammation of the gastrointestinal tract. In 2015, an estimated 3.1 million adults in the United States had ever received a diagnosis of IBD (1). Nationally representative samples ...

Last Updated: 31 Dec 1969

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Clostridium difficile infection in hospitalized patients with inflammatory bowel disease: Prevalence, risk factors, and prognosis.
 

Author(s): Nitsan Maharshak, Idan Barzilay, Hasya Zinger, Keren Hod, Iris Dotan

Journal: Medicine (Baltimore). 2018 Feb;97(5):e9772.

 

To evaluate the frequency, possible risk factors, and outcome of Clostridium difficile infection (CDI) in inflammatory bowel disease (IBD) patients.There has been an upsurge of CDI in patients with IBD who has been associated with increased morbidity and mortality. Various risk factors ...

Last Updated: 31 Dec 1969

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Relation of body mass index to risk of developing inflammatory bowel disease amongst women in the Danish National Birth Cohort.
 

Author(s): Michael Mendall, Maria Christina Harpsøe, Devinder Kumar, Mikael Andersson, Tine Jess

Journal:

 

Crohn's disease (CD) has traditionally been associated with weight loss and low BMI, yet paradoxically obesity has recently been suggested as a risk factor for CD, but not for ulcerative colitis (UC). We therefore hypothesized that the relation between BMI and CD is U shaped.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Inflammatory bowel disease" returned 942 free, full-text review articles on human participants. First 3 results:

A systematic review of cost-effectiveness studies comparing conventional, biological and surgical interventions for inflammatory bowel disease.
 

Author(s): Nadia Pillai, Mark Dusheiko, Bernard Burnand, Valérie Pittet

Journal:

 

Inflammatory bowel disease (IBD) is a chronic disease placing a large health and economic burden on health systems worldwide. The treatment landscape is complex with multiple strategies to induce and maintain remission while avoiding long-term complications. The extent to which rising ...

Last Updated: 31 Dec 1969

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Inflammatory bowel disease-specific health-related quality of life instruments: a systematic review of measurement properties.
 

Author(s): Xin-Lin Chen, Liang-Huan Zhong, Yi Wen, Tian-Wen Liu, Xiao-Ying Li, Zheng-Kun Hou, Yue Hu, Chuan-Wei Mo, Feng-Bin Liu

Journal:

 

This review aims to critically appraise and compare the measurement properties of inflammatory bowel disease (IBD)-specific health-related quality of life instruments.

Last Updated: 31 Dec 1969

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Inflammatory Bowel Disease and Risk of Ischemic Heart Disease: An Updated Meta-Analysis of Cohort Studies.
 

Author(s): Wan Feng, Guangxia Chen, Dawei Cai, Song Zhao, Jiafei Cheng, Hong Shen

Journal:

 

Several immune-mediated diseases have been shown to be associated with an increased risk of cardiovascular disease. However, studies evaluating the association between inflammatory bowel disease and risk of cardiovascular disease reported inconsistent results. We assessed the association ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Inflammatory Bowel Disease Registry in Daegu-Gyeongbuk
 

Status: Recruiting

Condition Summary: Idiopathic Chronic Inflammatory Bowel Disease

 

Last Updated: 23 Jul 2016

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Last Updated: 13 Sep 2017

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Nabilone Use For Acute Pain in Inflammatory Bowel Disease Patients
 

Status: Not yet recruiting

Condition Summary: Inflammatory Bowel Diseases

 

Last Updated: 30 Jan 2018

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