Inflammatory myofibroblastic tumor

Common Name(s)

Inflammatory myofibroblastic tumor

Inflammatory myofibroblastic tumor is made up of specific cells called myofibroblastic spindle cells. This tumor can occur in many different parts of the body, but it occurs most frequently in the lungs, soft tisues, or internal organs. Inflammatory myofibroblastic tumor usually develops in children or young adults, although it can affect people of any age. This type of tumor tends to recur in the same location, but it rarely spreads (metastasizes) to other parts of the body. Approximately 50% of inflammatory myofibroblastic tumors have rearrangements of the ALK gene on chromosome 2. Treatment typically involves surgery to remove the tumor.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Inflammatory myofibroblastic tumor" for support, advocacy or research.

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Inflammatory myofibroblastic tumor" returned 130 free, full-text research articles on human participants. First 3 results:

Imaging findings of inflammatory myofibroblastic tumor in breast: A case report.
 

Author(s): Xijin Mao, Hairong Liu, Jing Du, Ning Yu, Liang Chen, Lin Zhang

Journal: Medicine (Baltimore). 2018 Aug;97(32):e11804.

 

Inflammatory myofibroblastic tumors (IMTs), particularly breast IMTs, are rare neoplastic lesions typically associated with a favorable prognosis. Breast IMTs are easily misdiagnosed as other types of malignant lesions, and therefore there is a significant unmet need for a better ...

Last Updated: 31 Dec 1969

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The Clinical and Radiological Characteristics of Inflammatory Myofibroblastic Tumor Occurring at Unusual Sites.
 

Author(s): Xuewei Zeng, Huayi Huang, Jun Li, Jiayou Peng, Jiaxiong Zhang

Journal:

 

Inflammatory myofibroblastic tumor (IMT) can occur rarely in the soft tissue or joint of the limb. We retrospectively collected IMT cases of these rare sites and analyzed their clinical and imaging appearance. Thirteen cases of IMT were clinically diagnosed and underwent surgical ...

Last Updated: 31 Dec 1969

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Uterine metastases originating from a pulmonary inflammatory myofibroblastic tumor.
 

Author(s): Jun Zhang, Yuehong Li, Lei Lou

Journal: J Cancer Res Ther. 2018 ;14(Supplement):S257-S259.

 

Pulmonary inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal tumor, and is considered an inflammatory pseudotumor. Here, we report of a 37-year-old woman with severe cough and stridor who was diagnosed with primary IMT of the lungs, with adenocarcinoma in situ based on ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Inflammatory myofibroblastic tumor" returned 25 free, full-text review articles on human participants. First 3 results:

Inflammatory myofibroblastic tumor of the lung.
 

Author(s): Akshay Khatri, Abhinav Agrawal, Rutuja R Sikachi, Dhruv Mehta, Sonu Sahni, Nikhil Meena

Journal: Adv Respir Med. 2018 ;86(1):27-35.

 

Inflammatory myofibroblastic tumors (IMT) of the lung, first reported in 1939, are considered a subset of inflammatory pseudo -tumors. They are a distinctive lesions composed of myofibroblastic spindle cells accompanied by an inflammatory infiltrate of plasma cells, lymphocytes, and ...

Last Updated: 31 Dec 1969

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Uterine inflammatory myofibroblastic tumor: more common than expected: Case report and review.
 

Author(s): Vincenzo Dario Mandato, Riccardo Valli, Valentina Mastrofilippo, Alessandra Bisagni, Lorenzo Aguzzoli, Giovanni Battista La Sala

Journal: Medicine (Baltimore). 2017 Dec;96(48):e8974.

 

Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal neoplasm composed of spindled to epithelioid cells with prominent myxoid stroma and inflammatory infiltrate. It has a low but definite malignant potential. However, its management has never been standardized.

Last Updated: 31 Dec 1969

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Inflammatory myofibroblastic tumor of kidney together with ipsilateral perinephric and periureteric fibrosis: A case report and literature review.
 

Author(s): Zhuolun Sun, Hanbo Wang, Xudong Guo, Shaobo Jiang, Changying Jing

Journal: Medicine (Baltimore). 2017 Dec;96(49):e8807.

 

Both inflammatory myofibroblastic tumor (IMT) and retroperitoneal fibrosis are rare lesions, but kidney involvement is more rare. It is the first study about IMT of the kidney in a patient with perinephric and periureteric fibrosis and we hold that fibroblast proliferation may be ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Phase 1/2 Study of X-396, an Oral ALK Inhibitor, in Patients With ALK-positive Non-Small Cell Lung Cancer
 

Status: Recruiting

Condition Summary: Advanced Solid Tumors; Non-small Cell Lung Cancer

 

Last Updated: 12 Jul 2018

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Last Updated: 14 Oct 2018

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