Insulinoma

Common Name(s)

Insulinoma

An insulinoma is a tumor (growth) on the pancreas. It is usually benign, although it can occasionally be malignant (cancerous). The pancreas is responsible for the production of insulin, a messenger that tells the body to break down sugars to make energy needed for daily life. When there is a tumor on the pancreas, the pancreas may begin to produce too much insulin. When a person has too much insulin, their blood-sugar level can become very low, potentially causing seizures or confusion. Symptoms of insulinomas include anxiety, confusion, dizziness, headaches, and sweating. Treatment for insulinomas is usually surgery to remove the tumor as well as certain medications. With appropriate management, people with insulinomas can live full healthy lives.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Insulinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Insulinoma" returned 279 free, full-text research articles on human participants. First 3 results:

[High grade insulinoma detected in a patient with a 5-year history of severe hypoglycemias].
 

Author(s): Nadia Anoun, Hamza Hasnaoui, Firdaous Ameziane Hassani, Mehdi Bourakkadi Idrissi, Abdelmalek Ousadden, Hanan El Ouahabi, Khalid Ait Taleb

Journal:

 

Functional endocrine tumors of the pancreas are rare. Among them insulinomas are the most common types. The majority of the patients with insulinoma are between 30 and 60 years of age and 59% of them are women. Most insulinomas are sporadic tumors while 10% of them develop in patients ...

Last Updated: 31 Dec 1969

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Should the Selective Arterial Secretagogue Injection Test for Insulinoma Localization Be Evaluated at 60 or 120 Seconds?
 

Author(s): Keijiro Ueda, Tetsuhide Ito, Ken Kawabe, Lingaku Lee, Takashi Fujiyama, Yuichi Tachibana, Masami Miki, Kohei Yasunaga, Takehiro Takaoka, Akihiro Nishie, Yoshiki Asayama, Robert T Jensen, Yoshihiro Ogawa

Journal: Intern. Med.. 2017 Nov;56(22):2985-2991.

 

Objective The selective arterial secretagogue injection (SASI) test is considered indispensable for the accurate localization of insulinoma. However, the optimum timing of the post-injection evaluation is controversial, as some studies recommend 60 seconds [SASI (60 seconds)] while ...

Last Updated: 31 Dec 1969

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Insulinoma Presenting with Reactive Hypoglycemia: Evaluating the Effect of Tumor Resection via Continuous Glucose Monitoring.
 

Author(s): Tomohiko Kikuchi, Daisuke Chujo, Kazuhisa Takahashi, Nobuyuki Takahashi, Yuuki Tanno, Mie Tonoike, Noriko Ihana, Tetsuro Tsujimoto, Akiyo Tanabe, Hiroshi Kajio

Journal: Intern. Med.. 2017 Nov;56(22):3067-3071.

 

A 71-year-old woman previously diagnosed with reactive hypoglycemia was transferred to our emergency unit because of loss of consciousness. Her plasma glucose level was 27 mg/dL, and continuous glucose monitoring (CGM) revealed postprandial asymptomatic hypoglycemia. A hypervascular ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Insulinoma" returned 18 free, full-text review articles on human participants. First 3 results:

Successful EUS-guided ethanol ablation of insulinoma, four-year follow-up. Case report and literature review.
 

Author(s): Krzysztof Dąbkowski, Paula Gajewska, Kamila Walter, Magdalena Londzin-Olesik, Andrzej Białek, Elżbieta Andrysiak-Mammos, Beata Kos-Kudła, Teresa Starzyńska

Journal: Endokrynol Pol. 2017 ;68(4):472-479.

 

EUS-guided ethanol ablation of insulinoma is a new method of treatment of this neuroendocrine tumour. Ablation is recommended in patients who are poor surgical candidates or refuse surgery. We present a case of an 81-year-old female with symptomatic insulinoma, treated successfully ...

Last Updated: 31 Dec 1969

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Glycemic control in patients with insulinoma.
 

Author(s): Agata Matej, Hanna Bujwid, Jakub Wroński

Journal: Hormones (Athens). 2016 Oct;15(4):489-499.

 

Insulinoma is the most common neuroendocrine tumor of the pancreas. Surgical management of insulinomas is considered to be the only curative method. However, effective glycemic control preoperatively and in unresectable insulinomas remains a significant issue. Hyperinsulinism, occurring ...

Last Updated: 31 Dec 1969

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Insulinoma After Bariatric Surgery: Diagnostic Dilemma and Therapeutic Approaches.
 

Author(s): Christopher M Mulla, Alessandra Storino, Eric U Yee, David Lautz, Mandeep S Sawnhey, A James Moser, Mary-Elizabeth Patti

Journal: Obes Surg. 2016 Apr;26(4):874-81.

 

Hypoglycemia is increasingly recognized as a complication of bariatric surgery. Typically, hypoglycemia does not appear immediately postoperatively, but rather more than 1 year later, and usually occurs 1-3 h after meals. While rare, insulinoma has been reported after bariatric ...

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Diagnosing and Treating Low Blood Sugar Levels
 

Status: Recruiting

Condition Summary: Hypoglycemia; Insulinoma

 

Last Updated: 17 May 2018

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Pasireotide in Hyperinsulinemic Hypoglycemia
 

Status: Not yet recruiting

Condition Summary: Congenital Hyperinsulinism; Insulinoma; Hyperinsulinism

 

Last Updated: 14 Feb 2017

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18F-L-Fluoro-DOPA PET/CT Scan Localization of Focal Pancreatic Lesions in Subjects With Hyperinsulinemic Hypoglycemia
 

Status: Available

Condition Summary: Congenital Hyperinsulinism; Beckwith-Wiedemann Syndrome; Insulinoma

 

Last Updated: 15 Feb 2018

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