Interstitial Lung Disease

Common Name(s)

Interstitial Lung Disease

Interstitial lung disease describes a group of disorders caused by damage to the lungs, which are the organs through which we breathe. This damage can cause difficulty breathing and low oxygen levels in the blood. Although the exact cause of interstitial lung disease is unknown, it can be triggered by various injuries resulting in scarring within the lungs. Normally, the body fixes the damaged lung tissue, but in patients with interstitial lung disease the repair process does not function properly, causing thick and scarred air sacs. Other risk factors include long-term exposure to hazardous materials, certain autoimmune diseases, such as rheumatoid arthritis, age, and smoking. Once the lung tissue starts scarring, medication can only slow down the damage but it cannot reverse the damage. Treatment may include radiation, chemotherapy drugs, heart medications or antibiotics.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial Lung Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Interstitial Lung Disease" returned 574 free, full-text research articles on human participants. First 3 results:

Ultrasound B-lines in the evaluation of interstitial lung disease in patients with systemic sclerosis: Cut-off point definition for the presence of significant pulmonary fibrosis.
 

Author(s): Marika Tardella, Marco Di Carlo, Marina Carotti, Emilio Filippucci, Walter Grassi, Fausto Salaffi

Journal: Medicine (Baltimore). 2018 May;97(18):e0566.

 

The aim of this study was to establish the cut-off point of ultrasound (US) B-lines number for detecting the presence of significant interstitial lung disease (ILD) in patients with systemic sclerosis (SSc) (SSc-ILD) in relation to high-resolution computed tomography (HRCT) findings.Consecutive ...

Last Updated: 31 Dec 1969

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Successful treatment of plasma exchange for rapidly progressive interstitial lung disease with anti-MDA5 antibody-positive dermatomyositis: A case report.
 

Author(s): Yushiro Endo, Tomohiro Koga, Takahisa Suzuki, Kazusato Hara, Midori Ishida, Yuya Fujita, Sosuke Tsuji, Ayuko Takatani, Toshimasa Shimizu, Remi Sumiyoshi, Takashi Igawa, Masataka Umeda, Shoichi Fukui, Ayako Nishino, Shin-Ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Masataka Kuwana, Atsushi Kawakami

Journal: Medicine (Baltimore). 2018 Apr;97(15):e0436.

 

As the initial treatment of rapidly progressive interstitial lung disease (RPILD) with antimelanoma differentiation-associated gene 5 antibody (anti-MDA5 Ab)-positive dermatomyositis (DM) patients, a combination of corticosteroids, cyclophosphamide, and calcineurin inhibitor is recommended. ...

Last Updated: 31 Dec 1969

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Prevalence of lung cancer in patients with interstitial lung disease is higher than in those with chronic obstructive pulmonary disease.
 

Author(s): Hye In Jung, Jae Seok Park, Mi-Young Lee, ByeongJu Park, Hyun Jung Kim, Sun Hyo Park, Won-Il Choi, Choong Won Lee

Journal: Medicine (Baltimore). 2018 Mar;97(11):e0071.

 

We aimed to explore lung cancer prevalence in interstitial lung disease (ILD) patients with or without connective tissue disorder (CTD) and idiopathic pulmonary fibrosis (IPF) in comparison with chronic obstructive pulmonary disorder (COPD).We evaluated lung cancer prevalence associated ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Interstitial Lung Disease" returned 103 free, full-text review articles on human participants. First 3 results:

Treatment of connective tissue disease-associated interstitial lung disease: the pulmonologist's point of view.
 

Author(s): So-My Koo, Soo-Taek Uh

Journal: Korean J. Intern. Med.. 2017 Jul;32(4):600-610.

 

Interstitial lung disease (ILD) occurs in 15% of patients with collagen vascular disease (CVD), referred to as connective tissue disease (CTD). Despite advances in management strategies, ILD continues to be a significant cause of mortality in patients with CVD-associated ILD (CTD-ILD). ...

Last Updated: 31 Dec 1969

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British Lung Foundation/United Kingdom Primary Immunodeficiency Network Consensus Statement on the Definition, Diagnosis, and Management of Granulomatous-Lymphocytic Interstitial Lung Disease in Common Variable Immunodeficiency Disorders.
 

Author(s): John R Hurst, Nisha Verma, David Lowe, Helen E Baxendale, Stephen Jolles, Peter Kelleher, Hilary J Longhurst, Smita Y Patel, Elisabetta A Renzoni, Clare R Sander, Gerard R Avery, Judith L Babar, Matthew S Buckland, Siobhan Burns, William Egner, Mark M Gompels, Pavels Gordins, Jamanda A Haddock, Simon P Hart, Grant R Hayman, Richard Herriot, Rachel K Hoyles, Aarnoud P Huissoon, Joseph Jacob, Andrew G Nicholson, Doris M Rassl, Ravishankar B Sargur, Sinisa Savic, Suranjith L Seneviratne, Michael Sheaff, Prashantha M Vaitla, Gareth I Walters, Joanna L Whitehouse, Penny A Wright, Alison M Condliffe

Journal: J Allergy Clin Immunol Pract. ;5(4):938-945.

 

A proportion of people living with common variable immunodeficiency disorders develop granulomatous-lymphocytic interstitial lung disease (GLILD). We aimed to develop a consensus statement on the definition, diagnosis, and management of GLILD. All UK specialist centers were contacted ...

Last Updated: 31 Dec 1969

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Oxygen therapy for interstitial lung disease: a systematic review.
 

Author(s): Emily C Bell, Narelle S Cox, Nicole Goh, Ian Glaspole, Glen P Westall, Alice Watson, Anne E Holland

Journal:

 

This review aims to establish the impact of oxygen therapy on dyspnoea, health-related quality of life (HRQoL), exercise capacity and mortality in interstitial lung disease (ILD).We included studies that compared oxygen therapy to no oxygen therapy in adults with ILD. No limitations ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Interstitial Lung Disease Registry Construction
 

Status: Recruiting

Condition Summary: Interstitial Lung Disease

 

Last Updated: 1 Aug 2017

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Best Clinical Endpoints That Likely Induce Worse Prognosis in Interstitial Lung Diseases
 

Status: Recruiting

Condition Summary: Interstitial Lung Disease

 

Last Updated: 16 Jan 2018

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Last Updated: 25 Oct 2016

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