Invasive ductal carcinoma

Common Name(s)

Invasive ductal carcinoma, Invasive ductal carcinoma, breast cancer

Invasive ductal carcinoma (IDC) is a type of breast cancer that originates in the milk ducts and spreads to other tissue. Cancers form when a mutation in DNA causes certain cells to grow out of control, sometimes forming a lump or a tumor. Some of these cancerous cells can break off and spread to other parts of the body where they will continue to grow. This process is known as metastasis. IDC is the most common breast cancer, and it is also the only type of breast cancer that can be found in men. Many of the risk factors for breast cancer are related to estrogen exposure, such as older age, having children later in life, having few or no children, taking estrogen-containing medications, early menarche (first period), and late menopause. Other risk factors include increased alcohol intake, obesity, and family and individual history of certain types of cancer.

Symptoms of IDC include swelling of the breast, skin irritation (thickening, redness, or scales), nipple or breast pain, and irregular nipple discharge. A biopsy or sample of cells from the affected area can be performed to confirm the presence of cancer. Additional tests should be run to determine the extent and location of disease, and whether the cancer has spread. Often the first place that IDC spreads is to lymph nodes located above the breast and around the armpits. The stage of cancer will be determined based on the tumor size and whether it has spread to nearby lymph nodes or to other organs by metastasis.

Treatment options for IDC include surgery to remove the tumor, radiation therapy, chemotherapy, hormone (endocrine) therapy, and other targeted therapies. If you have been diagnosed with IDC, talk to your doctor about the best treatment options. In addition, a genetic counselor can help discuss inheritance and risks to other family members. Support groups are a good source of information and can connect you with others who have been affected by breast cancer.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Invasive ductal carcinoma" for support, advocacy or research.

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Bay Area Cancer Connections

We support people touched by breast and ovarian cancer by providing comprehensive, personalized services in an atmosphere of warmth and compassion.

Last Updated: 21 May 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Invasive ductal carcinoma" for support, advocacy or research.

Logo
Bay Area Cancer Connections

We support people touched by breast and ovarian cancer by providing comprehensive, personalized services in an atmosphere of warmth and compassion.

http://www.bcconnections.org

Last Updated: 21 May 2015

View Details

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Invasive ductal carcinoma" returned 310 free, full-text research articles on human participants. First 3 results:

Relationship Between ADAMTS8, ADAMTS18, and ADAMTS20 (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) Expressions and Tumor Molecular Classification, Clinical Pathological Parameters, and Prognosis in Breast Invasive Ductal Carcinoma.
 

Author(s): Xuhui Guo, Juntao Li, Hengwei Zhang, Hui Liu, Zhenzhen Liu, Xudong Wei

Journal:

 

BACKGROUND The aim of this study was to investigate the correlations between ADAMTSs expression and breast invasive ductal carcinoma (IDC), and to offer a theoretical basis for novel treatment methods for IDC patients. MATERIAL AND METHODS Non-proliferative catheter of breast fibroadenoma ...

Last Updated: 31 Dec 1969

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Development of ipsilateral chest wall spindle cell carcinoma in a patient with invasive ductal breast carcinoma during postoperative adjuvant therapy: A case report.
 

Author(s): Kaifu Li, Hua Kang, Yajun Wang, Tao Hai, Bixiao Wang

Journal: Medicine (Baltimore). 2018 May;97(19):e0739.

 

Metaplastic breast carcinoma (MBC) is rare subtype of breast carcinoma and is regarded as ductal carcinoma that undergoes metaplasia into a glandular growth pattern. Spindle cell carcinoma (SPC) is a subtype of MBC with a predominant spindle cell component.

Last Updated: 31 Dec 1969

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Modulation of Molecular Biomarker Expression in Response to Chemotherapy in Invasive Ductal Carcinoma.
 

Author(s): Mana Oloomi, Neda Moazzezy, Saeid Bouzari

Journal:

 

Breast cancer (BC) has varied morphological and biological features and is classified based on molecular and morphological examinations. Molecular classification of BC is based on biological gene-expression profiling. In this study, biomarker modulation was assessed during BC treatment ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Invasive ductal carcinoma" returned 12 free, full-text review articles on human participants. First 3 results:

Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in Invasive Breast Carcinoma and Ductal Carcinoma In Situ, Metastatic Tumor Deposits and Areas for Further Research.
 

Author(s): Shona Hendry, Roberto Salgado, Thomas Gevaert, Prudence A Russell, Tom John, Bibhusal Thapa, Michael Christie, Koen van de Vijver, M V Estrada, Paula I Gonzalez-Ericsson, Melinda Sanders, Benjamin Solomon, Cinzia Solinas, Gert G G M Van den Eynden, Yves Allory, Matthias Preusser, Johannes Hainfellner, Giancarlo Pruneri, Andrea Vingiani, Sandra Demaria, Fraser Symmans, Paolo Nuciforo, Laura Comerma, E A Thompson, Sunil Lakhani, Seong-Rim Kim, Stuart Schnitt, Cecile Colpaert, Christos Sotiriou, Stefan J Scherer, Michail Ignatiadis, Sunil Badve, Robert H Pierce, Giuseppe Viale, Nicolas Sirtaine, Frederique Penault-Llorca, Tomohagu Sugie, Susan Fineberg, Soonmyung Paik, Ashok Srinivasan, Andrea Richardson, Yihong Wang, Ewa Chmielik, Jane Brock, Douglas B Johnson, Justin Balko, Stephan Wienert, Veerle Bossuyt, Stefan Michiels, Nils Ternes, Nicole Burchardi, Stephen J Luen, Peter Savas, Frederick Klauschen, Peter H Watson, Brad H Nelson, Carmen Criscitiello, Sandra O'Toole, Denis Larsimont, Roland de Wind, Giuseppe Curigliano, Fabrice André, Magali Lacroix-Triki, Mark van de Vijver, Federico Rojo, Giuseppe Floris, Shahinaz Bedri, Joseph Sparano, David Rimm, Torsten Nielsen, Zuzana Kos, Stephen Hewitt, Baljit Singh, Gelareh Farshid, Sibylle Loibl, Kimberly H Allison, Nadine Tung, Sylvia Adams, Karen Willard-Gallo, Hugo M Horlings, Leena Gandhi, Andre Moreira, Fred Hirsch, Maria V Dieci, Maria Urbanowicz, Iva Brcic, Konstanty Korski, Fabien Gaire, Hartmut Koeppen, Amy Lo, Jennifer Giltnane, Marlon C Rebelatto, Keith E Steele, Jiping Zha, Kenneth Emancipator, Jonathan W Juco, Carsten Denkert, Jorge Reis-Filho, Sherene Loi, Stephen B Fox

Journal: Adv Anat Pathol. 2017 Sep;24(5):235-251.

 

Assessment of tumor-infiltrating lymphocytes (TILs) in histopathologic specimens can provide important prognostic information in diverse solid tumor types, and may also be of value in predicting response to treatments. However, implementation as a routine clinical biomarker has not ...

Last Updated: 31 Dec 1969

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Invasive ductal carcinoma of the breast with osteoclast-like giant cells and clear cell features: a case report of a novel finding and review of the literature.
 

Author(s): Nicole K Zagelbaum, Michael F Ward, Nader Okby, Howard Karpoff

Journal:

 

Osteoclast-like giant cells (OLGCs) are a rare histologic finding within a tumor of the breast. Although there has been discussion as to the pathogenesis and prognosis related to this finding, our understanding of its significance remains inconclusive. Clear cells are another unique ...

Last Updated: 31 Dec 1969

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Synchronous bilateral non-Hodgkin's diffuse large B-cell lymphoma of the breast and left breast invasive ductal carcinoma: a case report and review of literature.
 

Author(s): Weihua Liu, Hong Zhu, Xiaoge Zhou

Journal:

 

Lymphoma of the breast is unusual, and synchronous bilateral lymphoma and carcinoma of the breast is extremely rare. We present the case of a 51-year-old woman who found a mass in her left breast. Ultrasound scan findings revealed nodules at the 2 o'clock position in her left breast ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Palbociclib and Endocrine Therapy for LObular Breast Cancer Preoperative Study (PELOPS)
 

Status: Recruiting

Condition Summary: Breast Cancer

 

Last Updated: 30 Jan 2018

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Talimogene Laherparepvec in Combination With Neoadjuvant Chemotherapy in Triple Negative Breast Cancer
 

Status: Recruiting

Condition Summary: Breast Cancer; Ductal Carcinoma; Invasive Breast Carcinoma; Invasive Ductal Breast Carcinoma

 

Last Updated: 13 Jun 2018

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IORT Following Breast Conserving Surgery for Early Stage Breast Cancer Registry
 

Status: Recruiting

Condition Summary: Breast Cancer

 

Last Updated: 23 May 2018

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