Ischemic stroke

Common Name(s)

Ischemic stroke

A stroke occurs when the blood flow to the brain is interrupted or cut-off. When this happens, the affected area of the brain does not receive the oxygen and nutrients that it needs. An ischemic stroke is the most common type of stroke and is caused by a blockage in an artery leading to the brain. A blocked artery will cut-off blood supply to a region of the brain. If the blood supply is blocked for more than a few minutes, brain cells will begin to die.

The two types of ischemic strokes are thrombotic and embolic. These terms refer to the location of the blood clot. In a thrombotic stroke, a blood clot forms in one of the blood vessels in the brain. In an embolic stroke, a blood clot forms elsewhere in the body, such as in the heart, and then travels to the brain to cause a blockage.

Ischemic strokes have many potential causes. Excessive blood cholesterol will cause the arteries to narrow and eventually become blocked—resulting in a thrombotic stroke. Blood clots that form in the heart are another cause of ischemic strokes. This occurs when blood clot forms in the heart and then travels to the head, blocking blood supply to the brain. This type of stroke would be an embolic stroke. Blood clots in the heart are more likely to form in people who have irregular heartbeats, have had a heart attack, or have diseased heart valves. Other causes of ischemic strokes include street drug use, traumatic injury to the blood vessels of the neck, and blood clotting disorders.

The risk for stroke is higher in older adults, women, and individuals of African heritage. Other risk factors include high blood pressure, heart disease, smoking, or diabetes. Emergency personnel should be called immediately if you think that you or someone around you is experiencing a stroke. There are a number of complications that can occur after a stroke. Support groups are a great resource for more information and resources.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

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National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

Last Updated: 20 Feb 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Ischemic stroke" for support, advocacy or research.

Logo
National Stroke Association

National Stroke Association’s mission is to reduce the incidence and impact of stroke by developing compelling education and programs focused on prevention, treatment, rehabilitation and support for all impacted by stroke.

https://www.stroke.org

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Ischemic stroke" returned 4224 free, full-text research articles on human participants. First 3 results:

Generalization of the right acute stroke promotive strategies in reducing delays of intravenous thrombolysis for acute ischemic stroke: A meta-analysis.
 

Author(s): Qiang Huang, Jing-Ze Zhang, Wen-Deng Xu, Jian Wu

Journal: Medicine (Baltimore). 2018 Jun;97(25):e11205.

 

The generalization of successful efforts for reducing time delays in intravenous thrombolysis (IVT) could help facilitate its utility and benefits in acute ischemic stroke (AIS) patients.We searched the PubMed and Embase databases for articles reporting interventions to reduce time ...

Last Updated: 31 Dec 1969

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Age- and sex-related difference of lipid profile in patients with ischemic stroke in China.
 

Author(s): Pingsen Zhao, Sudong Liu, Zhixiong Zhong, Jing Liu

Journal: Medicine (Baltimore). 2018 Jun;97(23):e10930.

 

Age- and sex-related differences of lipid profiles were not well understood among ischemic stroke patients in China. Our study aimed to investigate the relationship between lipid abnormalities and ischemic stroke in China. A retrospective analysis was performed involving 2074 patients ...

Last Updated: 31 Dec 1969

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[Thrombolytic treatment of vertebro-basilar ischemic stroke in N'Djamena, Republic of Chad].
 

Author(s): Antoine Lamblin, Marc Bascou, Eve Drouard, Nicolas Alberti, Thierry de Greslan

Journal:

 

Ischemic stroke is rare among the French Armed Forces, but Army doctors on missions may be called on to manage it, in particular in sub-Saharan Africa. Therefore, this is a critical emergency requiring early multidisciplinary approach, with limited means, involving neurologists from ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Ischemic stroke" returned 542 free, full-text review articles on human participants. First 3 results:

Efficacy and safety of CYP2C19 genotype in stroke or transient ischemic attack patients treated with clopidogrel monotherapy or clopidogrel plus aspirin: Protocol for a systemic review and meta-analysis.
 

Author(s): Jia-Chen Yao, Min Cui, Mang-Mang Pan, Zhi-Chun Gu, Wen-Yan Li

Journal: Medicine (Baltimore). 2018 Jun;97(24):e11060.

 

The relationship of CYP2C19 genotype and clinical efficacy in stroke or transient ischemic attack (TIA) patients treated with clopidogrel monotherapy or clopidogrel plus aspirin remains unknown. We thus aim to conduct a meta-analysis to appraise evidence on the association of CYP2C19 ...

Last Updated: 31 Dec 1969

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The HindIII and PvuII polymorphisms of lipoprotein lipase (LPL) gene reduce the risk of ischemic stroke (IS): A meta-analysis.
 

Author(s): Limei Cao, Qiang Li, Xu Chen

Journal: Medicine (Baltimore). 2018 May;97(18):e0483.

 

Lipoprotein lipase (LPL) polymorphisms were suggested to be the risk factor for ischemic stroke (IS). However, controversial results were obtained. Our objective was to investigate the association of LPL polymorphisms at Ser447Ter, HindIII (+/-), and PvuII (+/-) with IS risk.

Last Updated: 31 Dec 1969

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Mechanical endovascular therapy for acute ischemic stroke: An indirect treatment comparison between Solitaire and Penumbra thrombectomy devices.
 

Author(s): Jonathan T Caranfa, Elaine Nguyen, Rafay Ali, Iregi Francis, Albert Zichichi, Elliott Bosco, Craig I Coleman, William L Baker, Christine G Kohn

Journal:

 

Randomized controlled trials (RCTs) have compared mechanical endovascular therapy (MET) in addition to intravenous tissue plasminogen activator (IVtPA) to IVtPA alone for the management of acute ischemic stroke (AIS). Direct comparative studies between individual METs are not available. ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 15 Nov 2017

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Predictors and Prognostic Factors on the Acute Ischemic Stroke
 

Status: Recruiting

Condition Summary: Ischemic Stroke

 

Last Updated: 3 Mar 2018

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