Juvenile idiopathic arthritis

Common Name(s)

Juvenile idiopathic arthritis, Pediatric arthritis, JIA, Juvenile rheumatoid arthritis, JRA

Juvenile idiopathic arthritis (JIA), also known as juvenile rheumatoid arthritis (JRA), is the most common form of arthritis in children ages 6 months to 17 years. JIA causes inflammation (redness, swelling, heat, pain) in one, or many, joints (areas of the body where two bones fit together). JIA is not the same as the adult type of arthritis. There are seven different types of JIA (see related conditions below).

JIA causes pain, stiffness, swelling, and redness most commonly in the knees and joints of hands and feet. The joint may not move fully (decreased range of motion). Symptoms are usually worse in the morning or after a nap. The symptoms may go away after a few months or be lifelong. Some types of JIA can affect other parts of the body, causing swollen lymph nodes, rashes and fever, eye inflammation and growth problems.

The cause of JIA is unknown (idiopathic). However, it is believed that both environmental and genetic factors play a role. JIA may be an autoimmune or autoinflammatory disease. Usually, our immune system protects us from illness and infection by attacking viruses, bacteria and other foreign bodies. Sometimes our immune system attacks its own healthy cells. Different parts of our immune system can go wrong causing either an autoimmune or an autoinflammatory response.

Girls are more likely to have JIA. Certain viruses may also increase a child’s risk. To diagnose this condition, your child’s doctor or specialist may perform a physical exam, blood tests and special imaging tests of your child’s joints (using X-ray, MRI and video imaging). Although there is no cure for JIA, there are treatments that help reduce pain and swelling. These treatments include medications, therapy, and possibly surgery. If your child has been diagnosed with JIA, talk with their doctor about the most current treatment options. Support groups are also a good source of information and will help connect you with other families.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Juvenile idiopathic arthritis" for support, advocacy or research.

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International Foundation for Autoimmune Arthritis

We are committed to eliminating the adversity caused by autoimmune arthritis by uniting resources that will raise global awareness, providing wellness education and support, and conducting patient-centered research that will improve the quality of life for those affected by these diseases.

Last Updated: 18 Sep 2014

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International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

Last Updated: 18 Apr 2010

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Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

Last Updated: 2 Aug 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Juvenile idiopathic arthritis" for support, advocacy or research.

Logo
International Foundation for Autoimmune Arthritis

We are committed to eliminating the adversity caused by autoimmune arthritis by uniting resources that will raise global awareness, providing wellness education and support, and conducting patient-centered research that will improve the quality of life for those affected by these diseases.

http://www.ifautoimmunearthritis.org

Last Updated: 18 Sep 2014

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International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

http://www.sclero.org/

Last Updated: 18 Apr 2010

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Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

http://www.isabellasaviary.com

Last Updated: 2 Aug 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Juvenile idiopathic arthritis" returned 721 free, full-text research articles on human participants. First 3 results:

Predictors of methotrexate response in Turkish children with oligoarticular and polyarticular juvenile idiopathic arthritis.
 

Author(s): Ezgi Deniz Batu, Hafize Emine Sönmez, Bora Gülhan, Zehra Serap Arıcı, Rezan Topaloğlu, Yelda Bilginer

Journal: Turk. J. Pediatr.. 2017 ;59(1):6-12.

 

Batu ED, Sönmez HE, Gülhan B, Arıcı ZS, Topaloğlu R, Bilginer Y. Predictors of methotrexate response in Turkish children with oligoarticular and polyarticular juvenile idiopathic arthritis. Turk J Pediatr 2017; 59: 6-12. Methotrexate (MTX) is the most commonly used disease modifying ...

Last Updated: 31 Dec 1969

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A fatal case of tuberculous meningitis in a child with juvenile idiopathic arthritis: a diagnostic challenge.
 

Author(s): Zumrut Sahbudak Bal, Pinar Yazici, Semra Sen, Cenk Eraslan, Cengiz Cavusoglu, Bulent Karapinar, Fadil Vardar

Journal: Rev. Soc. Bras. Med. Trop.. ;50(5):709-711.

 

The prognosis of tuberculous meningitis, a rare form of extrapulmonary tuberculosis, depends on the stage of treatment initiation. We report a fatal case of tuberculous meningitis. The patient had received successive tumor necrosis factor (TNF) antagonists and abatacept to treat juvenile ...

Last Updated: 31 Dec 1969

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Development of a national audit tool for juvenile idiopathic arthritis: a BSPAR project funded by the Health Care Quality Improvement Partnership.
 

Author(s): Flora McErlane, Helen E Foster, Gillian Armitt, Kathryn Bailey, Joanna Cobb, Joyce E Davidson, Sharon Douglas, Andrew Fell, Mark Friswell, Clarissa Pilkington, Helen Strike, Nicola Smith, Wendy Thomson, Gavin Cleary

Journal: Rheumatology (Oxford). 2018 Jan;57(1):140-151.

 

Timely access to holistic multidisciplinary care is the core principle underpinning management of juvenile idiopathic arthritis (JIA). Data collected in national clinical audit programmes fundamentally aim to improve health outcomes of disease, ensuring clinical care is equitable, ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Juvenile idiopathic arthritis" returned 103 free, full-text review articles on human participants. First 3 results:

Open issues in the assessment and management of pain in juvenile idiopathic arthritis.
 

Author(s): Gabriella Giancane, Alessandra Alongi, Silvia Rosina, Serena Calandra, Alessandro Consolaro, Angelo Ravelli

Journal: Clin. Exp. Rheumatol.. ;35 Suppl 107(5):123-126.

 

Pain is the major symptom of children with juvenile idiopathic arthritis (JIA) and its reduction is a key goal of treatment. It is widely agreed that assessment of pain is a fundamental component of the rheumatology evaluation and should be carried out at each clinic visit. However, ...

Last Updated: 31 Dec 1969

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Harnessing interactive technologies to improve health outcomes in juvenile idiopathic arthritis.
 

Author(s): Andrea Coda, Dean Sculley, Derek Santos, Xavier Girones, Lucie Brosseau, Derek R Smith, Joshua Burns, Keith Rome, Jane Munro, Davinder Singh-Grewal

Journal:

 

Children and adolescents with Juvenile Idiopathic Arthritis (JIA) typically have reduced physical activity level and impaired aerobic and anaerobic exercise capacity when compared to their non-JIA counterparts. Low intensity exercise regimens appear to be safe in children with JIA ...

Last Updated: 31 Dec 1969

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Clinical improvement of renal amyloidosis in a patient with systemic-onset juvenile idiopathic arthritis who received tocilizumab treatment: a case report and literature review.
 

Author(s): Songkiat Chantarogh, Soamarat Vilaiyuk, Thipwimol Tim-Aroon, Suchin Worawichawong

Journal:

 

Juvenile idiopathic arthritis (JIA) is a common rheumatic disease in children and adolescents. Although JIA may cause secondary amyloidosis, this is a rare complication in patients with JIA and other rheumatic diseases. Many previous studies have revealed that common heterozygous ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pharmacovigilance in Juvenile Idiopathic Arthritis Patients Treated With Biologic Agents and/or Methotrexate
 

Status: Recruiting

Condition Summary: Juvenile Idiopathic Arthritis

 

Last Updated: 2 Mar 2018

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Massage Therapy in Juvenile Idiopathic Arthritis
 

Status: Recruiting

Condition Summary: Juvenile Idiopathic Arthritis

 

Last Updated: 28 Mar 2018

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