Keratoconus

Common Name(s)

Keratoconus

Keratoconus is the degeneration of the structure of the cornea, which is the clear tissue covering the front of the eye. In this condition, the shape of the cornea slowly changes from the normal round shape to a cone shape. Most people who develop keratoconus start out nearsighted, which tends to become worse over time. The cause is unknown, but the tendency to develop keratoconus is probably present from birth. Keratoconus is thought to involve a defect in collagen, the tissue that makes up most of the cornea. Some researchers believe that allergy and eye rubbing may play a role.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Keratoconus" for support, advocacy or research.

National Keratoconus Foundation

The National Keratoconus Foundation (NKCF) is an outreach program of the Discovery Eye Foundation. The NKCF dedicated to the dissemination of information about keratoconus to patients, their families, and eye care professionals.

Last Updated: 15 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Keratoconus" for support, advocacy or research.

National Keratoconus Foundation

The National Keratoconus Foundation (NKCF) is an outreach program of the Discovery Eye Foundation. The NKCF dedicated to the dissemination of information about keratoconus to patients, their families, and eye care professionals.

http://www.nkcf.org/

Last Updated: 15 Feb 2013

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General Support Organizations

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General Resources

KC-Link and NKCF Forum

Email and Web based Support groups

Updated 15 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Keratoconus" returned 470 free, full-text research articles on human participants. First 3 results:

Palmoplantar Keratoderma with Keratoconus.
 

Author(s): Ved Prakash Gupta, Isha Chaudhari

Journal: Middle East Afr J Ophthalmol. ;25(1):49-51.

 

Palmoplantar keratodermas (PPKs) are a rare heterogeneous group of disorders characterized by abnormal thickening of the skin of palms and soles. Ocular manifestations reported with palmer planter keratosis include scleral melanosis, macular deposits, and congenital cataract. We report, ...

Last Updated: 31 Dec 1969

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Comparison of Anterior, Posterior, and Total Corneal Astigmatism Measured Using a Single Scheimpflug Camera in Healthy and Keratoconus Eyes.
 

Author(s): Young Choi, Youngsub Eom, Jong Suk Song, Hyo Myung Kim

Journal: Korean J Ophthalmol. 2018 06;32(3):163-171.

 

To compare the effect of posterior corneal astigmatism on the estimation of total corneal astigmatism using anterior corneal measurements (simulated keratometry [K]) between eyes with keratoconus and healthy eyes.

Last Updated: 31 Dec 1969

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Conventional and transepithelial corneal cross-linking for patients with keratoconus.
 

Author(s): Xiaoyu Zhang, Jing Zhao, Meiyan Li, Mi Tian, Yang Shen, Xingtao Zhou

Journal:

 

Previous studies investigating the effectiveness of conventional corneal collagen cross-linking (CXL) and transepithelial CXL in keratoconus treatment have reported conflicting outcomes. Therefore, we conducted a meta-analysis to compare the effectiveness of these treatments. We searched ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Keratoconus" returned 51 free, full-text review articles on human participants. First 3 results:

Graft survival rate of deep anterior lamellar keratoplasty for keratoconus: A meta-analysis.
 

Author(s): Meng Guan, Weijia Zhao, Yang Zhang, Yu Geng, Zonghan Chen, Liuyan Feng, Dongli Li, Ling Yuan

Journal: Medicine (Baltimore). 2018 Jul;97(28):e11404.

 

Deep anterior lamellar keratoplasty (DALK) is an optional treatment for patients with keratoconus, and the associated graft survival rate varies. Herein, we aimed to explore the graft survival rate of DALK in patients with keratoconus.

Last Updated: 31 Dec 1969

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Efficacy and safety of transepithelial corneal collagen crosslinking surgery versus standard corneal collagen crosslinking surgery for keratoconus: a meta-analysis of randomized controlled trials.
 

Author(s): Wenwei Li, Bin Wang

Journal:

 

The aim of this study was to evaluate the efficacy and safety of transepithelial corneal collagen crosslinking (transepithelial CXL) versus standard corneal collagen crosslinking (epithelium-off CXL) on keratoconus.

Last Updated: 31 Dec 1969

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Corneal Collagen Cross-Linking for Keratoconus: Systematic Review.
 

Author(s): Hidenaga Kobashi, Shi Song Rong

Journal: Biomed Res Int. 2017 ;2017():8145651.

 

To evaluate the efficacy of collagen cross-linking (CXL) one year after treatment for keratoconus compared to no treatment by summarizing randomized controlled trials (RCTs) using a systematic review.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Corneal Tissue Inlay for Keratoconus
 

Status: Recruiting

Condition Summary: Keratoconus

 

Last Updated: 24 Aug 2017

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The Role of Antioxidant Supplementation in Keratoconus Patients
 

Status: Not yet recruiting

Condition Summary: Keratoconus

 

Last Updated: 20 Apr 2018

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Intacs for Keratoconus
 

Status: Recruiting

Condition Summary: Keratoconus

 

Last Updated: 1 Feb 2018

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