Keratolytic winter erythema

Common Name(s)

Keratolytic winter erythema, Ichthyosis, erythrokeratolysis hemalis

Keratolytic winter erythema, also known as Oudtshoorn skin disease, is characterized by a cyclical disruption of normal epidermal keratinization primarily affecting the palmoplantar skin with peeling of the palms and soles. The condition is worse in the winter (summary by {4:Hull et al., 2013}).
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Keratolytic winter erythema" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Keratolytic winter erythema" returned 3 free, full-text research articles on human participants. First 3 results:

Duplicated Enhancer Region Increases Expression of CTSB and Segregates with Keratolytic Winter Erythema in South African and Norwegian Families.
 

Author(s): Thandiswa Ngcungcu, Martin Oti, Jan C Sitek, Bjørn I Haukanes, Bolan Linghu, Robert Bruccoleri, Tomasz Stokowy, Edward J Oakeley, Fan Yang, Jiang Zhu, Marc Sultan, Joost Schalkwijk, Ivonne M J J van Vlijmen-Willems, Charlotte von der Lippe, Han G Brunner, Kari M Ersland, Wayne Grayson, Stine Buechmann-Moller, Olav Sundnes, Nanguneri Nirmala, Thomas M Morgan, Hans van Bokhoven, Vidar M Steen, Peter R Hull, Joseph Szustakowski, Frank Staedtler, Huiqing Zhou, Torunn Fiskerstrand, Michele Ramsay

Journal: Am. J. Hum. Genet.. 2017 May;100(5):737-750.

 

Keratolytic winter erythema (KWE) is a rare autosomal-dominant skin disorder characterized by recurrent episodes of palmoplantar erythema and epidermal peeling. KWE was previously mapped to 8p23.1-p22 (KWE critical region) in South African families. Using targeted resequencing of ...

Last Updated: 31 Dec 1969

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Physical and transcriptional map of the critical region for keratolytic winter erythema (KWE) on chromosome 8p22-p23 between D8S550 and D8S1759.
 

Author(s): Silke Appel, Matthias Filter, André Reis, Hans Christian Hennies, Anton Bergheim, Emma Ogilvie, Silke Arndt, Andrew Simmons, Michael Lovett, Winston Hide, Michèle Ramsay, Kathrin Reichwald, Wolfgang Zimmermann, André Rosenthal

Journal: Eur. J. Hum. Genet.. 2002 Jan;10(1):17-25.

 

Keratolytic winter erythema is an autosomal dominant skin disorder characterised by erythema, hyperkeratosis, and peeling of the skin of the palms and soles, especially during winter. The keratolytic winter erythema locus has been mapped to human chromosome 8p22-p23. This chromosomal ...

Last Updated: 31 Dec 1969

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Localization of the gene causing keratolytic winter erythema to chromosome 8p22-p23, and evidence for a founder effect in South African Afrikaans-speakers.
 

Author(s): M Starfield, H C Hennies, M Jung, T Jenkins, T Wienker, P Hull, A Spurdle, W Küster, M Ramsay, A Reis

Journal: Am. J. Hum. Genet.. 1997 Aug;61(2):370-8.

 

Keratolytic winter erythema (KWE), also known as "Oudtshoorn skin disease," or "erythrokeratolysis hiemalis," is an autosomal dominant skin disorder of unknown etiology characterized by a cyclical erythema, hyperkeratosis, and recurrent and intermittent peeling of the palms and soles, ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

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The terms "Keratolytic winter erythema" returned 0 free, full-text review articles on human participants.

 
 
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